Metabolic Flashcards

1
Q

What are 3 examples of metabolic brain pathologies?

A
  • hepatic encephalopathy
  • thiamine deficiency
  • uraemic seizures
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2
Q

How does hepatic encephalopathy present?

A
  • altered mentation or generalised forebrain signs such as seizures
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3
Q

Cause of hepatic encephalopathy

A
  • secondary to congenital or acquired portosystemic shunting
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4
Q

Diagnosis of hepatic encephalopathy

A
  • dynamic bile acid testing
  • ammonia is useful but can be tricky and unreliable
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5
Q

Fill in the gaps: all animals less than xx months of age which present with xx should be screened for HE secondary to congenital xx xx

A
  • All animals less than 12m/o which present with seizures should be screened for HE secondary to congenital portosystemic shunting
    – they rarely present with seizures related to feeding
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6
Q

Cause of thiamine deficiency

A
  • cats on raw fish diets
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7
Q

Signs of thiamine deficiency

A
  • generalised changes in the brain, so present with progressive forebrain or vestibular signs
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8
Q

Prevalence of thiamine deficiency

A
  • very rare in dogs and cats on a reputable commercial diet
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9
Q

Uraemic seizures

A
  • seizures can occur in animals with severe uraemia, however will be showing other signs indicative of severe renal compromise
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