Mesenteric ischemia Flashcards
Acute mesenteric ischemia causes:
- embolic occlusion of artery
- thrombosis of artery
- intense splanchnic vasoconstriction (nonocclusive) - hypovolemia or low flow state
- mesenteric vein occlusion
most common cause of mesenteric ischemia
SMA thrombosis
What type of mesenteric ischemia presents with acute onset abdominal pain in a patient with history of recent cardiac event or prior embolization?
embolism of SMA
What type of mesenteric ischemia presents with acute onset abdominal pain in the setting of chronic abdominal pain associated with food aversion/weight loss and PVD?
SMA thrombosis
What type of mesenteric ischemia presents with waxing and waning abdominal pain depending on HDS or abdominal distention in the setting of worsening acidosis in an unresponsive patient?
nonocclusive mesenteric ischemia (NOMI)
What type of mesenteric ischemia presents with vague/nonspecific abdominal complaints (nausea, vomiting, diarrhea, nonspecific abdominal pain) that is not acute? Seen in patients with hx of PE, oral contraceptives, estrogen supplementation, hypercoagulable, hx of cancer
mesenteric vein thrombosis
What is the fastest and most useful test to diagnose mesenteric ischemia?
CTA
Medical treatment adjuncts of acute mesenteric ischemia:
resuscitated to correct acid/base abonormalities, anticoagulation with heparin, start antibiotics
Surgical treatment of acute embolic mesenteric ischemia?
heparinize; expose the SMA: reflect transverse colon superiorly and retract small bowel to right upper quadrant, divide ligament of treitz, palpate SMA over the 3rd and 4th portions of duodenum
obtain proximal and distal control of SMA
transverse arteriotomy and embolectomy with balloon catheter
vein patch to close arteriotomy
Assess bowel viability, second look operation before definitive closure
Surgical treatment of acute thrombotic mesenteric ischemia?
treatment consists of a bypass procedure
- antegrade or retrograde: supraceliac aorta, infrarenal aorta, or iliac artery
- conduit is reverse grater saphenous vein or dacron
- assess bowel viability
antegrade bypass for acute thrombotic mesenteric ischemia steps:
divide gastrohepatic ligament and mobilize left lobe of liver
esophagus retract to left
divide diaphgragmatic crura and median arcuate ligament
vein graft is bypassed first to the celiac artery and then to the SMA by tunneling behind the pancreas
steps of retrograde bypass for acute thrombotic mesenteric ischemia:
most proximal SMA segment that is patent is exposed
anastomois is completed and the bowel returned to anatomic position
Bypass graft is pulled and placed adjacent to the aorta to a soft spot on the infrarenal aorta or the iliac artery
what other intervention besides surgery can be attempted for patients with acute embolic & thrombotic mesenteric ischemia who are poor surgical candidates?
mesenteric angiography with trials of lytic therapy, balloon angioplasty, stent placement
Management of nonocclusive mesenteric ischemia ?
largely supportive; can also inject vasodilators such as papaverine as an adjunct with angiography
Surgical management of mesenteric venous thrombosis:
evaluate for hypercoagulaable states; surgical exploration should be reserved for bowel ischemia and infarction; venous thrombectomy has not been shown to be effective; thrombolytics may be helpful