Mental Health - Pharmacology Flashcards
1
Q
What are some side effects of SSRIs?
A
- Nausea
- Flushing
- Sexual dysfunction
- Bleeding
- Discontinuation Syndrome
2
Q
What are some SNRI side effects?
A
NA - Dry mouth, sweating, blurred vision
5HT - SSRI side effects (Sexual dysfunction, transient increased anxiety, nausea, constipation)
3
Q
Benzos MOA?
A
Bind at interface of GABA(A) alpha and gamma subunits to potentiate its effect -> increase Cl channel opening -> Increase threshold -> decrease Action potentials -> decrease NT release -> inhibitory effect
4
Q
What are some benzos side effects?
A
- Dependence
- Withdrawal
- Cognitive impairment
- Falls risk
- Paradoxical aggression
5
Q
Which pathway is responsible for schizophrenia positive symptoms?
A
Mesolimbic - increased DA here
6
Q
Which pathway is responsible for schizophreia negative symptoms?
A
Mesocortical - decreased DA here
