mental health Flashcards
what permits release of neurotransmitters
Conduction in a presynaptic cell permits the release of neurotransmitters
production and release of neurotransmitters can be altered by…
The production and release of neurotransmitters can be altered by other chemicals, cell damage, how the neurotransmitters are taken back up by the pre-synaptic cell, etc.
there is competition for different neurotransmitters at…
There is competition for different neurotransmitters at the receptor cite
receptor cites are also modified by…
Receptor cites are also modified by other chemicals, which can change their ability to receive different neurotransmitters
dopamine
Involved in fine muscle movement, integration of thoughts and emotions (pleasure and energy), decision making (motivation)
where is dopamine produced
Produced in the Substantia nigra
dopamine has an inverse relationship with…
Dopamine has an inverse relationship with gamma-amino butyric (GABA)
Dopamine is excitatory and GABA is calming. Therefore an increase in dopamine means a decrease in GABA
dopamine strives to have a 50/50 balance with…
Dopamine strives to have a 50:50 balance with acetylcholine
When this balance is disrupted movement disorders can occur
excess and insufficient dopamine
Excess= Mania (symptoms include psychosis, hallucinations, aggression and anxiety)
Insufficiency= Depression and Parkinson’s Disease
norepinephrine
Converted from Dopamine
When there is excess dopamine there will be excess norepinephrine
norepinephrine causes changes in…
Causes changes in
Mood
Attention
Arousal/energy (stimulates sympathetic nervous system for the fight or flight stress response)
excess and insufficient norepinephrine
Excess= mania, anxiety
Insufficiency= depression, anhedonia
serotonin involved in…
Involved in Sleep regulation Hunger Mood Pain perception Aggression Sexual behavior
excess and insufficient serotonin
Excess= anxiety
Insufficiency= Depression
bipolar type 1
one or more manic or mixed episodes, usually accompanied by major depressive episodes
bipolar type 2
one or more major depressive episodes, usually accompanied by at least one hypomanic episode
bipolar type cyclothymic (rapid cycling)
At least two years of numerous periods of hypomanic symptoms that do not meet the criteria for a manic episode and numerous periods of depressive symptoms that do not meet the criteria for a major depressive episode.
bipolar type 1 prevalence
Median age of onset is 18 years of age
More common in men
More likely to include legal problems and acts of violence
Most often begins with a depressive episode
bipolar type 2 prevalence
Median age of onset is 18 years of age Most common form of bipolar disorder More common in women More likely to include substance abuse, Commonly misdiagnosed as major depressive disorder or personality disorder
bipolar type cyclothymic prevalence
Median age of onset is early adulthood
comorbidities for bipolar (mental health diagnoses)
Panic attacks, alcohol abuse, social phobia, seasonal affective disorder
comorbidities for bipolar (physical health concerns)
Chronic fatigue syndrome, asthma, migraine, chemical sensitivity, hypertension, bronchitis, gastric ulcers
presence of comorbidities in bipolar increases the…
Complexity of the treatment
Ability of the patient, and possibly his or her supports to work
Patient’s dependence on others
Patient’s general health care needs
etiology of bipolar: biological factors: genetic
Strong Heritability
Increases by 5-10% if a relative has bipolar disorder
Polygenic disease
It has been suggested that there are multiple genes that contribute to the expression of bipolar
Irregularities on chromosomes 13 and 15
Some evidence to suggest that these chromosomes contribute to alterations in thought process
etiology of bipolar: biological factors: neurobiological
The proportions of neurotransmitters (Norepinephrine, dopamine, and serotonin are disrupted
The sensitivity of the neurotransmitter receptors are changed
The function of neurotransmitters is linked to hormones
Pre-frontal cortex (impaired executive and cognitive functioning)
Limbic regions of the brain are most severely affected
etiology of bipolar: biological factors: neuroendocrine
Hypothalamic-pituitary-thyroid-adrenal (HPTA) axis
Hypothyroidism is known to be associated with depressed mood
etiology of bipolar: biological factors: gender
Although there are differences in the prevalence of gender between the types of bipolar, overall the rate of bipolar disorder is relatively equal between men and women
However, women are more likely to be hospitalized
Hospitalization most often occurs between the ages of 40-44
etiology of bipolar: psychological factors: environmental
Increased stress
Can be either a significant event or prolonged exposure of less intensity
Once the presentation of bipolar is trigger by a stressful event, the environmental stress is no longer needed to perpetuate the disorder
etiology of bipolar: psychological factors: socioeconomic determinants of health
More prevalent in higher socioeconomic classes
Individuals with bipolar achieve higher education as well as higher occupational status than those with unipolar depression
The proportion of individuals with bipolar disorder among creative writers, actors etc is higher than the general public
schizophrenia and other psychotic disorders: DSM V classification identifies this group of disorders as…
devastating brain disorders that impact:
Cognition Language Emotions Social behavior Movement
positive symptoms of psychosis
Presence of delusions, hallucinations, overtly disorganized thinking and behaviors
Contribute to poor social functioning
May have sudden onset and improve with antipsychotic medication
negative symptoms of psychosis
Absence of thought and behavior patterns that contribute to inappropriate social functioning and poor social functioning
Usually slow onset and worsen over the course of the illness
Examples: withdrawn, alienating/isolating, does not attend to hygiene and other ADLs, unable to make decisions or to follow through on a plan
psychotic disorder prevalence: brief psychotic disorder
Occurs in adolescence and across the lifespan
Average onset is in the mid 30s
Twice as common in females
Occurs more frequently in developing countries
psychotic disorder etiology
The etiology for brief psychotic disorders may vary depending on the circumstances.
As a result, it is important to complete a thorough assessment of the individuals signs and symptoms, and the context.
Psychosis is evident in changes in mental status and behavior, and can occur as a result of changes in an individuals physical status, major life events, recreational drug use, and environmental changes.
schizophrenia subtypes
paranoid, schizoaffective
schizophrenia prevalence
Onset is usually late teens and early adolescents
Becomes chronic or recurrent in 80% of individuals who are diagnosed
More common in males (almost 1 ½ x)
Associated with poor functioning before the onset of the disease
schizophrenia etiology: biological factors: genetics
Heredity
Polygenic disease
Irregularities on chromosomes 13 and 15
schizophrenia etiology: biological factors: neurobiological
Neurotransmitters
dopamine, and serotonin, glutamate
schizophrenia etiology: biological factors: brain structure abnormalities
Differences in the size, shape and symmetry of the ventricles
Lower brain volume
Increased cerebrospinal fluid
Slower blood flow to the frontal lobe
schizophrenia etiology: psychological and environmental factors: prenatal stressors
Prenatal risk factors include viral infections, poor nutrition, hypoxia, exposure to toxins
Birth complications
Age of parents at conception
schizophrenia etiology: psychological and environmental factors: psychological stressors
Prolonged increased stress
Exposure to recreational drugs
Psychological trauma
schizophrenia etiology: psychological and environmental factors: socioeconomic determinants of health
Adverse living conditions
Migration
delusional disorder subtypes
erotomania
grandiose
jealous
somatic
delusional disorder prevalence
Rare to exist on its own
Co-morbidities include: mood disorders, OCD, personality disorders Many individuals can live undiagnosed because their behavior is not noticeably abnormal
Can begin in adolescence
Affects men and women equally
comorbidities of delusional disorder
mood disorders, OCD, personality disorders (specifically paranoid, schizoid, avoidant
delusional disorder etiology: neurobiological
Asymmetrical temporal lobes
Possible neuro-degenerative component
Sensory alterations in the nervous system associated with cortical changes
Perceptions become linked with an interpretation that has deep emotional significance but no verifiable basis
delusional disorder etiology: socioeconomic determinants of health
Influence of early life experiences
what does a good assessment allow a nurse to do?
Respect the patient’s experience.
The details help us accurately understand the context and relevance of the patient’s problem.
Makes it easier to identify connections between various assessments
Help the patient see their problem differently and identify their own solutions to resolve the problem.
Increase the patient’s and families buy-in for the treatment plan.
Enables nurses to check their own biases.
Enables nurses to synthesize the assessment data with other nursing knowledge to provide holistic, safe care
Makes it sustainable
Reduce stigma
bipolar areas for assessment
MSE
Risk Assessment
Physical Assessment
Family
Evaluation of the quality of the patient’s supports
Increased divorce rates
Increased frequency of hospital admissions
SEDoHs
An inquiry about the patient’s internal and external resources
bipolar assessment: MSE general appearance (depression)
grooming = range from disheveled to adequate care of self
dress = may wear same clothing for several days, stay in pajamas, or may get dressed
make up = not wear any
movement: slowed
engagement = difficult to engage and distracted, guarded
bipolar assessment: MSE general appearance (mania)
grooming = well groomed
dress = may be well dressed, wear limited clothing, or bright colours
make up = may be grossly overdone
movement = purposeful
engagement = easily engaged and distracted, uninhibited
bipolar assessment: MSE affect and mood (depression)
affect = flat, withdrawn, blunted, teary mood = low congruence = affect and mood will be congruent appropriateness = affect is usually appropriate to the context
bipolar assessment: MSE affect and mood (mania)
affect = unstable range of emotions (euphoric to angry), labile mood = 10/10 congruence = affect and mood may be congruent appropriateness = affect is usually not appropriate to the context
bipolar assessment: MSE speech and language (depression)
rate = slow volume = quiet rhythm = may be hesitant, uneven vocabulary = may be simple and limited
bipolar assessment: MSE speech and language (mania)
rate = speeded volume = loud rhythm = pressured vocabulary = may be expansive and flamboyant
bipolar assessment: MSE thought process (depression)
linear = depends on the severity of the depression
goal directed = may have difficulty either finding the words to articulate his/her thoughts or might not be able to concentrate to follow the discussion
may observe = poverty of speech, perseveration
bipolar assessment: MSE thought process (mania)
linear = no, the patient will cover multiple topics in a very short time span, and usually dos not complete one topic before moving on to the next
goal directed = may have difficulty either finding the words to articulate his/her thoughts or might not be able to concentrate to follow the discussion
may observe = circumstantiality, tangentiality, loose association, flight of ideas, and perseveration
circumstantiality
over-inclusive, indirect, eventually reaches the goal but is delayed