Mental Health Flashcards

1
Q

Define alcohol dependence

A
  • Characterised by THREE OR MORE of the following:
    (o Withdrawal on cessation of alcohol
    o Tolerance
    o Compulsion to drink, difficulty controlling termination or levels of use
    o Persistent desire to cut down or control use
    o Time is spent obtaining, using or recovering from alcohol
    o Neglect of other interests (social, occupations or recreational)
    o Continued use despite physical and psychological problems )
  • Recommended weekly amount < 14 units/week (1 unit = 8 g of alcohol)
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2
Q

Explain the aetiology/risk factors of alcohol dependence

A
  • Genetic factors
  • Environmental factors (upbringing)
  • Patients with depressive and anxiety states are at increased risk
  • Alcohol Withdrawal Pathophysiology
    (o Alcohol:
    (* Enhances inhibitory GABA activity
  • Inhibits excitatory glutamate neurotransmission )
    o Chronic alcohol exposure leads to a compensatory reduction in GABA receptor function and upregulation of excitatory glutamate receptors
    o Abrupt alcohol cessation leads to overactivation of these excitatory receptors)
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3
Q

Summarise the epidemiology of alcohol dependence

A
  • US prevalence: 2-9%
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4
Q

Recognise the presenting symptoms of alcohol dependence

A
  • History of heavy drinking
  • CAGE Questions
    (o Have you felt like you should Cut down on drinking?
    o Have you felt Annoyed by people telling you to stop drinking?
    o Have you ever felt Guilty about how much you drink?
    o Do you feel like you need a drink to wake you up (Eye-opener)? )
  • Check for other comorbidities/risk factors (e.g. smoking, depression)
* Symptoms of Withdrawal 
(o Nausea 
o Sweating 
o Tremor 
o Restlessness 
o Agitation 
o Visual hallucinations 
o Confusion 
o Seizures)
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5
Q

Recognise the signs of alcohol dependence on physical examination

A
* Signs of chronic alcohol misuse 
(o Dupuytren's contracture 
o Palmar erythema 
o Bruising 
o Spider naevi 
o Telangiectasia 
o Facial mooning 
o Bilateral parotid enlargement 
o Gynaecomastia 
o Smell of alcohol )
* Signs of complications (e.g. alcoholic hepatitis, liver failure)
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6
Q

Identify appropriate investigations for alcohol dependence

A
* Bloods 
(o Macrocytic anaemia 
o High GGT 
o High AST/ALT 
o Others: high uric acid, high triglycerides, markers of organ damage (e.g. long PT) )
* Acute Overdose 
(o Blood alcohol 
o Glucose 
o ABG 
o U&amp;Es 
o Toxic screen (check for drug overdose e.g. barbiturates, paracetamol))
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7
Q

Define anxiety disorder

A
  • A group of mental disorders characterised by feelings of anxiety or fear.
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8
Q

Explain the aetiology/risk factors of anxiety disorder

A
  • It is a syndrome of ongoing anxiety and worry about many events or thoughts that the patient generally recognises as excessive and inappropriate
  • Risk Factors
    (o Being aged 35-54
    o Being divorced or separated
    o Living alone or as a single parent )
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9
Q

Summarise the epidemiology of anxiety disorder

A
  • Lifetime prevalence of about 5%

* More common in WOMEN

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10
Q

Recognise the presenting symptoms and signs of anxiety disorder

A
* Diagnostic criteria for anxiety disorder:
(o Excessive anxiety and worry occurring more days than not for at least 6 months 
o Patient finds it difficult to control the worry 
o Anxiety and worry are associated with 3 or more of the following symptoms: 
(* Restlessness 
* Easily fatigued 
* Difficulty concentrating 
* Irritability 
* Muscle tension 
* Sleep disturbance ))
* Autonomic arousal symptoms: 
(o Palpitations 
o Sweating 
o Trembling 
o Dry mouth )
* Chest and abdomen symptoms: 
(o Difficulty breathing 
o Feeling of choking 
o Chest pain or discomfort 
o Nausea/abdominal pain )
* Symptoms involving mental state: 
(o Dizziness/light-headedness 
o Feeling of losing control 
o Fear of dying )
* General symptoms: 
(o Hot flushes and cold chills 
o Numbness and tingling sensation 
o Muscle tensions or aches and pains 
o Restlessness 
o Globus )
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11
Q

Identify appropriate investigations for anxiety disorder

A
  • It is a CLINICAL diagnosis
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12
Q

Define depressive disorders

A
  • A mood disorder that causes a persistent feeling of sadness and loss of interest.
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13
Q

Explain the aetiology/risk factors of depressive disorders

A
  • NICE recommends the use of DSM-IV classification to diagnose depression
  • Major depression requires at least one of the core symptoms:
    (o Persistent sadness or low mood nearly every day
    o Loss of interests or pleasure in most activities )
  • Along with some of the following symptoms:
    (o Fatigue or loss of energy
    o Worthlessness, excessive or inappropriate guilt
    o Suicidal thoughts
    o Diminished ability to think or concentrate
    o Psychomotor agitation and retardation
    o Insomnia
    o Changes in appetite and/or weight loss )
  • Symptoms should have persisted for at least 2 weeks
  • Risk Factors
    (o Being FEMALE
    o Past history of depression
    o Significant physical illness causing disability or pain
    o Other mental health problems (e.g. dementia)
    o Being part of a refugee community )
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14
Q

Summarise the epidemiology of depressive disorders

A
  • 5% of adults will have a depressive episode every year

* 1/4 women will develop depression severe enough to require treatment at some point in their lives

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15
Q

Recognise the presenting symptoms and signs of depressive disorders

A
  • Look above at the aetiology learning objectives
  • Somatisation (physical symptoms resulting from psychiatric illness) is a very important signs and must not be missed
  • Elderly people may present with depressive pseudodementia (altered memory and behaviour that mimics dementia)
  • Assessment Tools
    (o Patient Health Questionnaire (PHQ-9)
    o Hospital Anxiety and Depression (HAD) Scale
    o Beck’s Depression Inventory )
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16
Q

Identify appropriate investigations for depressive disorders

A
  • Consider organic causes to the depression (e.g. hypothyroidism, hypercalcaemia, Addison’s disease, Cushing’s disease)
  • Investigations for other causes:
    (o Blood glucose
    o U&Es
    o TFTs
    o Calcium
    o FBC
    o MRI/CT )