Mental Health Flashcards

1
Q

What are the three core symptoms of depression according to ICD-10 criteria?

A

Low mood
Anhedonia
Anergia/fatigue

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2
Q

Other than the core symptoms what are some other features of depression?

A
Disturbed sleep with early morning wakening
Poor concentration 
Low self confidence
Poor or increased appetite
Suicidal thoughts or acts
Psychomotor retardation
Guilt or self blame
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3
Q

Important questions to ask in depression to rule out other things?

A

Hypomanic or manic episodes- bipolar disorder
Normal reaction to grief
Medical disorders - chronic eg hypothyroidism, MS, alcohol and substance abuse

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4
Q

Medication associated with depression

A
Corticosteroids 
Beta blockers
Statins
Oral contraceptives 
Isotretinoin
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5
Q

Manic symptoms

A

Symptoms that affect social or occupational functioning or psychosis or hospitalisation distinguishes it from hypomanic
Abnormally elevated, expansive or irritable mood
Abnormal and persistent increased activity or energy
Inflated self esteem, grandiosity, flight of thoughts
Unrestrained buying, spending or gambling sprees
No drugs or other causes

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6
Q

Side effects of sertraline

A

GI upset, dry mouth, decreased libido or sexual activity, reduced ability to orgasm, mild nausea, drowsiness
Uncommon- weight gain, tremor, palpitations, urinary incontinence, urinary retention

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7
Q

When to refer to psychiatric services ?

A
  • significant perceived risk of suicide, harm to others or severe self neglect
  • if there are psychotic symptoms
  • if there is a history or clinical suspicion of bipolar disorder
  • in all cases where child or adolescent is presenting with major depression
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8
Q

Assessing suicide risk

A
Thoughts of suicide or self harm
What precipitated attempt
Why then, there and now
Planned or impulsive
Suicide note left
Intoxicated
Any precautions against discovery
Previous attempts at suicide or self harm
How do they feel now
Do a PHQ9
Is there support at home
Any risks to anyone
Are there children at home
How do they feel about the future
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9
Q

What increases risk of suicide ?

A
Age over 45
Male
Family history of depression, substance misuse or suicide 
Unemployed
Physical illness
Psychiatric illness
Divorced or widowed or single
Personal substance misuse
Previous attempts
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10
Q

Treatment of mild depression

A

Do not routinely medicate but consider use if there is moderate to severe recurrent depression or depression has persisted for more than 2-3 months
Offer low intensity psychosocial intervention eg self guided CBT, computerised CBT, structured group physical activity programme

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11
Q

Treatment of moderate or severe depression

A

Provide a combo of antidepressant meds and high intensity psychological intervention such as CBT

  1. SSRI- sertraline or citalopram
  2. SNRI- venlafaxine, mirtazapine
  3. Add an augmenting agent eg second gen antipsychotic such as quetiapine or lithium
  4. Tri cyclic - amitriptyline
  5. MAOI
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12
Q

Important things to check in treatment resistant depression

A
Check diagnosis
Check alcohol or drug abuse
Further antidepressant trials
ECT
Neurosurgery
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13
Q

Electroconvulsive therapy

A

Most effective treatment for severe depression, life threatening depression, prolonged or severe mania, Catatonia

SE- memory loss, short term retrograde amnesia, confusion, headaches, clumsiness

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14
Q

Generalised anxiety disorder symptoms

A

Psychological- constant worries, pervasive feeling of apprehension or dread, poor concentration, frustration, instability to tolerate uncertainty
Physical- trembling, sweating, nausea, SOB, difficulty swallowing, hot flashes, headaches, muscle ache or tension, twitching, irritability, insomnia, feeling in the edge, restlessness
Behavioural-putting things off due to feeling overwhelmed, avoidance, drug taking

More than 6 months and not tied to specific situation or OCD

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15
Q

Things to exclude in GAD

A
Phobia
Hyperthyroidism 
Angina
Asthma
Excessive caffeine
Alcohol 
Drugs
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16
Q

Treatment for GAD

A

Simple lifestyle changes- increase exercise, improve work life balance, avoid excess caffeine and stimulant drugs, avoid excess alcohol
Long term interventions such as CBT, SSRI self help
Benzos not to be used for more than 2-4 weeks due to tolerance and dependence

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17
Q

Benzodiazepines

A

Symptoms of anxiety reduces in 30-90 minutes

SE- sedation, reps depression, tolerance, dependence, impaired cognition

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18
Q

Discontinuation of antidepressants

A

Do slowly over a period of at least four weeks to prevent withdrawals and a recurrence of symptoms
Stop at an appropriate time and not during times of stress

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19
Q

Antidepressant discontinuation syndrome

A

Common symptoms- dizziness, headache, nausea, lethargy

Rarer- ataxia, electric shock sensations, EPSE, hypomania or mania

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20
Q

Differentials of psychosis

A
Schizophrenia
Bipolar
Delirium
Drug induced 
Encephalitis
Thyroid disease
Brain tumour
Hugh dose steroids
Temporal lobe epilepsy
Dementia
Brain injury
Metabolic disorders
Lupus 
Drug withdrawal
21
Q

Treatment of psychosis

A

Antipsychotic medication
CBT
Social support

22
Q

Questions to ask in psychosis

A
Describe experience
When did last feel normal
How have things changed since then
Ask about social life, family, friends, interests
Auditory hallucinations - describe the voice, what does it say, what does it sound like, 
Other strange or frightening experiences
Tv or radio talking about or to you
Paranoia
Special powers?
23
Q

Side effects of antipsychotics

A
Weight gain, diabetes. Metabolic syndrome, hyperlipidaemia
Sedation
Movement disorders
Prolonged QT
Raised prolactin (mainly in clozapine)
24
Q

Monitoring with antipsychotics

A
Weight 
Waist circumference
Pulse 
BP
Fasting blood glucose
Blood lipid profile
Prolactin levels
Assess for movement disorders
ECG if necessary
25
What is section 2 of MHA?
Person can be detained under section two if suffering from mental health condition which warrants their detention in hospital with a view to the protection of themselves or others Under section two if not assessed in hospital before or have not been assessed for a while Lasts 28 days
26
Section 3 of MHA
Detained in hospital for treatment Can follow a section two Up to 6 months Force treatment for first three months but needs reassessing after 3 months
27
Section 4 of MHA
72 hour emergency hold for treatment
28
Positive symptoms of schizophrenia
Delusions | Hallucinations
29
Negative symptoms of schizophrenia
Blunted mood Reduced speech Poor self care Loss of volition
30
Thoughts changes in schizophrenia
Disorders of speech Tangential Knights move Neologisms
31
Causes or increased risk of schizophrenia
Birth asphyxia, childhood encephalitis, sexual abuse, cannabis, separation from parent, born in city Increased risk in Afro Caribbean and south Asian patients Poor prognosis gradual onset, strong family history, low IQ, premorbid hisorur of social withdrawal and lack of obvious precipitation
32
Types of schizophrenia
Paranoid- commonest subtype, hallucinations and delusions Hebephrenic- age of onset 15-25, poor organisms, flu testin affect prominent with fleeting fragmented delusions and hallucinations Catatonic- characterised by stupor, posturing, waxy flexibility, negativity Simple and residual- negative symptoms predominant
33
Risk factors for delirium
``` CHIMPS PHONED Constipation Hypoxia Metabolic disturbance Pain Sleepnlessness Prescriptions Hypothermia or Pyrexia Organ dysfunction eg hepatic or renal failure Nutrition Environmental changes Drugs ```
34
What to ask in delirium history
History of dementia or depression Look for infection Medications- opiates or calcium supplements Vascular problems-previous MI, limb ischaemia (vascular dementia RF) Other presenting complaints History of recurrent admissions
35
What is involved in a confusion screen?
Early warning score BP and pulse (check for sepsis, dehydration, hypotension) Obs CT head- bleeds, strokes, SOL Bloods- FBC (anaemia, WCC, MCV), U&Es (electrolyte imbalance high calcium, dehydration), LFT (alcohol intake, liver failure), TFTs, calcium, b12, glucose, CXR, blood cultures upfield query sepsis, urine dip for UTI
36
Differentials for memory problems
``` Alzheimer’s Vascular dementia Dementia with Lewy Bodies Traumatic brain injury Frontotemporal dementia Semantic dementia Creutzfeldt Jakob disease Normal pressure hydrocephalus Wernicke Korsakoff Pseudo dementia secondary to depression Confusion secondary to infection ```
37
Tests and tools to assess confusion and cognition
Addenbrookes cognitive assessment Montreal cognitive assessment- MoCA Mini mental state exam Hospital anxiety and depression scale
38
Vascular dementia
Usually caused by an acute, such as stroke or TIA Can also develop over time from small blockages or slowing of blood Risk factors- diabetes, hypertension, high cholesterol, CHD, peripheral artery disease Step like decline in memory or cognition Lower the vascular risk- aspirin and statins
39
Alzheimer’s
Most common form of dementia Usually Begins in 60s Risk factors- age, genetics Gradual downward slope decline, starting from memory, thought and language,
40
Clinical presentation of Alzheimer’s
Involvement in cortical function eg aphasia, agnosia, apraxia Decrease of motivation and drive Slow rate of progression CT and MRI show cerebral atrophy Hallucinations, delusions, anxiety, marked agitation, aggression, agitation, wandering, hoarding, sexual inhibition
41
Genetics with dementia
Early onset is autosomal dominant so 50% chance of getting it. 50% of those with Down’s syndrome who live to 60 will get AD Late onset genetics- apolipoprotein E (E4 increases risk, E3 normal risk, E2 reduced risk)
42
Pharmacological management of Alzheimer’s and Lewy Body
Cholinesterase inhibitors - donepezil Rivastigmine Memantine- NMDA receptor blockers Meds slow down progress of the disease Delays worsening of dementia for 6-12 months
43
Non pharmacological treatment for dementia
``` CBT reminiscence therapy Aromatherapy Sensory stimulation Music therapy ```
44
Criteria for dementia
``` Decline in memory, decline in emotional control or motivation Apathy Coarsening of social behaviour Must not have delirium Must be present for at least 6 months Should be irreversible ```
45
Lewy body dementia
Memory impairment Sleep disturbances- nightmares, aggressive movements, disturbed sleep cycle Autonomic dysregulation Variable cognition Urinary incontinence Visual spatial difficulties, language impairment, dyspraxia Memory, motor and psychosis Deposits of alpha synuclein Memory difficulties and problems develop at least one year before motor Give rivastigmine and maybe memantine
46
Parkinson’s dementia
One third with PD develop dementia Memory and psychotic symptoms develop one year after motor difficulties Also alpha synuclein deposits
47
Front- temporal dementia
Frontal lobe- behaviour, problem solving, executive function (planning) Temporal lobe- language, recognising objects and people Lost inhibitions, lose empathy, apathy, change in eating habits
48
Borderline personality disorder
Impulsive aggression, affective lability, self injury and identity diffusion Unstable self image, fears of abandonment, transient psychotic symptoms, Maladaptive patterns of thought and behaviour Treatment- co morbidities such as anxiety and depression, CBT, DBT,
49
Mental state exam
Appearance- overall impression, physical conditions suitability of dress, cleanliness Behaviour- appropriateness of behaviour, distractibility, eye contact, rapport Speech- rate, rhythm, volume, tone, coherence, relevance, quantity and fluency, abnormal associations, flight of ideas Mood Perception- delusional perception, illusion, hallucination Thought- form- linear, tangential, circumferential, derailment Content- suicidal or violent thoughts, delusions, overvalued ideas Cognition- alert, attention concentration, orientation to time and place, short term memory Insight- recognition of illness and need for treatment