Mental Health Flashcards
Who does depression affect?
F:M
2:1
What causes depression?
Combination of biopsycosocial causes throughout pts life
Cause not known fully
What are the risk factors for depression?
Genetics Childhood experience Personality traits (neuroticism, anxiety, impulsivity, obessionality) Social circumstances - marital status - adverse life events Physical illness
What are the symptoms for depression?
Present for at least 2 weeks
Not secondary to drugs/alcohol/medication/bereavement
Core symptoms:
- depressed mood (most of the day, nearly every day)
- anhedonia
- weight change
- disturbed sleep
- fatigue/loss of energy
- reduced libido
- feelings of worthlessness
- diminished concentration
- suicidal thoughts (may/may not been acted on)
What are the signs of depression on examination?
Psychomotor agitation/retardation
What are the differential diagnoses of depression?
Other psychiatric disorders Neurological disorders Endocrine disorders Metabolic disorders Anaemia SLE
What are the treatments for depression?
Mild-moderate
- watch wait
- CBT
Moderate- severe
- antidepressants + CBT
- ECT
- psychiatric referral
- exercise
Pharmacological
- tricyclic antidepressants - amytriptyline
- monoamine oxidase inhibitors (MAOIs) - Isocarboxazid
- selective serotonin reuptake inhibitors (SSRIs) - citalopram, fluoxetine
How common is anxiety?
Prevalence 2.5-6%
Who does anxiety affect?
F>M
Single
Unemployed
What are the causes of anxiety?
Genetics 30%
Neurobiological
- ANS responsiveness
- loss of control of cortisol
- abnormal behaviour inhibition system
- neurotransmitter abnormalities (⬇️ GABA, ⬇️5-HT)
Psychological
- experience of unexpected negative events (rape, war, loss of parent)
- chronic stressors (family, marriage)
- parental issues (overprotective, unresponsive, not-loving)
What are the risk factors for anxiety?
Stressful event Other anxiety disorders Depression, dysthymia Alcohol/drug issues Physical problems ➡️ IBS, atypical chest pain
What are the symptoms of anxiety?
Must be present every day for more than 6 months
DSM-IV ➡️ at least 3 of:
- restlessness/feeling on edge
- easy fatigability
- concentration difficulty/mind blanking
- irritability
- muscle tension
- sleep disturbance
ICD-10 ➡️ at least 4 of:
- autonomic arousal - palpitations, tachycardia, sweating, trembling, shaking, dry mouth
- physical - breathing difficulties, choking sensation, chest pain/discomfort, nausea/abdo distress
- mental state - dizzy, unsteady, faint/lightheaded, derealisation/depersonalisation, fear of losing control/passing out/dying
- general - hot flushes, cold chills, numbness/tingling
- tension - muscle aches/pains, muscle tension, inability to relax
- other - exaggerated response to minor surprise
What are the differential diagnoses of anxiety?
Normal worries
Depression (mixed with anxiety)
Drug/alcohol misuse
Medical condition (arrhythmias, HF, asthma, COPD, hyperthyroidism)
Drug side effects (anti hypertensives, anti arrythmics, bronchodilators, anticonvulsants, anticholinergics)
What are the treatment options for anxiety?
Psychological - CBT
Behavioural - treat avoidance with exposure, relaxation methods, controlling hyperventilating
Pharmacological - Buspirone Benzodiazepines Tricyclic antidepressants Beta blockers
How common is alcohol dependence?
~180,000 prescriptions for alcohol dependence in primary care
Who does alcohol dependence affect?
M>F
Young
What are the causes of alcohol dependence?
Genetics - 2x risk if 1st degree relative
What are the risk factors for alcohol dependence?
Lower socioeconomic groups
Lower educational levels
Occupation (industry workers, travelling salesman, doctors)
What are the signs of alcohol dependence?
An overwhelming desire for alcohol
Drinking out of control
A need for increasing amounts of alcohol
Withdrawal symptoms experienced
Having little interest in other activities
Continuing to drink even when the harm being done is made clear
What investigations are necessary to diagnose alcohol dependence?
CAGE questionnaire
- ever felt you should Cut back?
- anyone Annoyed you by criticising your drinking?
- ever felt Guilty about your drinking?
- ever needed a drink first thing as an Eye-opener
2+ then ask ➡️
- what’s the most alcohol you’ve drunk in a day?
- what’s the most you’ve drunk in a week?
Alcohol Use Disorders Identification Test (AUDIT)
- breath testing - blood alcohol conc correlated with breathalyser results
- gives recent alcohol consumption
Bloods - ⬆️ MCV, carbohydrate-deficient transferrin (CDT) = markers for excessive alcohol consumption
- FBC, LFT
What are the complications of alcohol dependence?
Hepatitis Liver cirrhosis Anaemia Cardiomyopathy Coma Hypoglycaemia AKI