Mental Health Flashcards
What is the therapeutic range for Lithium?
0.4-1.0 mmol/L
Indication of lithium
Bipolar disorder
When do the lithium levels need to be checked when dose changed?
1 week
What is knight’s move
illogical leaps from one idea to another
What is flight of ideas?
Discernible links between ideas
What are the common features of PTSD?
1) Re-experiencing
2) Avoidance
3) Hyperarousal
4) emotional numbing
Management of PTSD
- CBT or eye movement desensitisation and reprocessing
- Drug is not routine 1st line : Venlafaxine or SSRI (sertraline)
What ECG changes does Citalopram cause?
QT prolongation and Torsades de pointes
What are the examples of SSRI?
Citalopram
sertraline
Fluoxetine
Side effect of lorazepam
Anterograde amnesia
What should be monitored when initiating and titrating venlafaxine?
Blood pressure (HTN)
What is 2nd line option for depression?
SNRI - venlafaxine
What signs should be monitored when taking antidepressants?
Hyponatraemia
What is life-threatening side-effect of clozapine?
Agranulocystosis/Neutropenia
What is agranulocystosis?
Decreased WCC, primarily neutrophils
What is the 1st line medication for GAD?
SSRI - specifically Sertraline
What is the stepwise approach for managing GAD?
1) Patient education + monitor condition
2) Low-intensity psychological intervention
3) High-intensity psychological intervention. -drug treatment/CBT
4) highly specialist input
What is the management of severe OCD - (severe functional impairment)?
- SSRI and CBT (including ERP)
What are the side effects of typical antipsychotics?
- Acute dystonia (e.g. torticollis, oculgyric crisis)
- Parkinsonism
- Akathisia (severe restlessness)
- Tardive dyskinesia
- Neuroleptic malignant syndrome
What is torticollis?
- Unilateral pain and deviation of the neck with pain on palpation and restricted range of motion
What is neuroleptic malignant syndrome?
- Altered MSE
- Generalised rigidity
- Fever
- Fluctuating blood pressure
What is tardive dyskinesia?
- uncontrolled facial movements such as lip-smacking
- usually caused by long term use of antipsychotics
What are examples of typical antipsychotics?
- Haleperidol
- Chlopromazine
What are examples of atypical antipsychotics?
- Clozapine
- Risperidone
- Olanzapine