Menopause Study Tip Gal

Question 1

Estrogen

Answer 1

■ Most effective treatment for vasomotor symptoms.

Question 2

Estrogen in Women with a uterus; use in combination with a form of progesterone (e.g., a progestin).

Answer 2

Unopposed estrogen increases tiierisk o f endometrial cancer.

Question 3

Estrogen is associated with significant safety risks including:

Answer 3

boxed warnings for VTE, stroke, dementia and
breast cancer (bigger concern in the elderly).

Question 4

Progestins (e.g., norethindrone, levonorgestrel, drospirenone) can be given as part o f a combination pill (with estrogen) or as a separate tablet, most commonly medroxyprogesterone (MPA),

Answer 4

Can cause mood disturbances, which may be intolerable; if taken intermittently (e,g„ for two weeks per month as with Premphase), spotting can occur.

Question 5

Micronized progestins

Answer 5

(e,g„ Prometrium) are considered to be safer than synthetic progestins (e,g„ medroxyprogesterone).