Meningococcal Vaccine

Question 0

What is the most common Meningococcal Serotype in Canada?

Answer 0

B (No vaccine against it)

Question 1

What are the two types of Meningococcal Vaccines?

Answer 1

MCV-C (Serotype C) and MCV-4 (Serotype A, C, Y, W-135).

Question 2

What is the worst Serotype of Neisseria Menincococci?

Answer 2

C. Reduced in recent history.

Question 3

When should we give the first Meningococcal vaccine, which one, and why?

Answer 3

At 12 years. Earlier doesn’t give sustained protection. Earlier if at high risk (2 months). The MCV-C should be given first to give protection against the worst one, and the MCV-4 not too effective this early.

Question 4

When does meningococcal strain C usually hit?

Answer 4

15-19 years old.

Question 5

What is the mortality rate of invasive meningococcal disease?

Answer 5

10%. Worse if C or septicaemia disease.

Question 6

When does Serotype Meningococcal B usually hit?

Answer 6

Less than 5. 70% of cases.

Question 7

Why is there no vaccine for Serotype B meningococcus?

Answer 7

Polysaccharides against B are very poorly immunogenic.

Question 8

At what age should MCV-4 be given?

Answer 8

About 12 years of age. (Grade 7)

Question 9

What are the high risk meningococcal risk factors?

Answer 9

Anatomical or functional a splenic (SCD!)
Primary antibody deficiency disorders.
Complement disorders.
Military
Lab personnel with exposure to meningococcus, high risk areas.

Question 10

What are the more common names for MCV-4 and MCV-C?

Answer 10

MCV-4 - Menactra.

MCV-C - Menjugate.