Meningitis Flashcards

1
Q

Give the 5 most common bacteria that cause meningitis:

A

1) Neisseria meningitidis
2) Streptococcus pneumonia
3) Haemophilus influenzae
4) Group B Strep (Strep. agalactiae)
5) Listeria monocytogenes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What two bacteria are associated with bacterial meningitis in neonates?

A

1) Group B Strep
2) Listeria monocytogenes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Is N. meningitidis gram positive or gram negative?

A

gram negative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is meningococcal meningitis?

A

N. meningitidis bacterial infection of the meninges and cerebrospinal fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is meningococcal septicaemia?

A

when the N. meningitidis bacteria infection is in the blood stream (here, you will see the non-blanching rash)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Give the 3 most common viral causes of meningitis:

A

1) Enteroviruses e.g. Coxsackie virus
2) Herpes simplex virus
3) Varicella zoster virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What drug is used to treat viral meningitis?

A

aciclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What test can be done on a CSF sample to check for viral meningitis?

A

viral PCR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Give 7 symptoms associated with meningitis:

A

1) fever
2) photophobia
3) headache
4) seizures
5) vomiting
6) neck stiffness
7) altered consciousness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

In what disease would meningitis present with a non-blanching rash?

A

meningococcal septicaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Give 4 meningitis signs and symptoms seen in neonates:

A

1) hypotonia (absence of muscle tone)
2) poor feeding
3) lethargy
4) bulging fontanelle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Name two special tests for meningitis:

A

1) Kernig’s test
2) Brudzinski’s test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Describe Kernig’s test for meningitis:

A

lay the patient on their back and flex one hip and knee to 90 degree - then slowly straighten the knee while the hip is flexed - this will stretch the meninges and create pain and resistance in meningitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe Brudzinskii’s sign for meningitis:

A

lay the patient flat on their back and gently lift their head - in meningitis, the patient will involuntarily flex their knees and hips

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

At which vertebral level does the spinal cord end?

A

L1/L2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

At what vertebral level is a lumbar puncture need inserted?

A

L3/L4

17
Q

What blood sample is sent off along CSF analysis in meningitis to allow for comparison?

A

Blood glucose

18
Q

Describe the appearance of bacterial CSF:

A

Cloudy

19
Q

Describe the appearance of viral CSF:

A

Clear

20
Q

Is CSF protein level high, low or normal in bacterial meningitis?

A

high

21
Q

Is CSF protein level high, low or normal in viral meningitis?

A

normal (maybe slightly raised)

22
Q

Is CSF glucose high, low or normal in bacterial meningitis?

A

Low

23
Q

Is CSF glucose high, low or normal in viral meningitis?

A

normal

24
Q

What white cells are abundant in bacterial meningitis CSF?

A

neutrophils

25
Q

What white cells are abundant in viral meningitis CSF?

A

lymphocytes

26
Q

True or false: bacterial meningitis is a medical emergency

A

true

27
Q

What drug should children with suspected meningitis and a non-blanching rash be given in primary care while awaiting transfer to hospital?

A

IM/IV benzylpenicillin

28
Q

What blood test should be completed if meningococcal infection is suspected?

A

meningococcal PCR (tests for N. meningitidis DNA and is often faster than blood cultures)

29
Q

What antibiotics should be given to bacterial meningitis patients under 3 months?

A

1) cefotaxime
2) amoxicillin

30
Q

What antibiotic should be given to bacterial meningitis patients above 3 months?

A

Cefotaxime

31
Q

What additional antibiotic should be given if penicillin-resistant pneumococcal infection is suspected in bacterial meningitis?

A

vancomycin

32
Q

What drug class can be given to reduce the risk of complications such as hearing loss and neurological deficit in bacterial meningitis?

A

steroids (e.g. dexamethasone)

33
Q

True or false: bacterial meningitis and meningococcal infection are notifiable diseases to the UK Health Security Agency

A

True

34
Q

What drug should be given to people who have been in close contact with a meningococcal patient within 7 days before the onset of their illness as post-exposure prophylaxis?

A

single dose ciprofloxacin

35
Q

Give 5 potential complications of meningitis:

A

1) hearing loss (common)
2) seizures and epilepsy
3) cognitive impairment and learning disability
4) memory loss
5) focal neurological deficits such as limb weakness of spasticity