Meningcoccal disease

Question 1

2 types of meningococcal diseases

Answer 1

Septicaemia + Meningitis

Question 2

Meningococcal Septicaemia

Answer 2

Bacteria multipy

Question 3

What is the causative organism

Answer 3

Neisseria Meningitides (Meningococcus) - Aerobic gram negative bacterium
Humans are the only reservoir

Question 4

How come they have pathogenic subtypes?

Answer 4

They have a polysaccharide capsule that resists pathogenesis and lysis

Question 5

How many subtypes

Answer 5

13

Question 6

Transmission of meningococcal disease

Answer 6

Aerosol
Droplets
Direct contact with respiratory secretions

Question 7

Risk factors of meningococcal disease

Answer 7

Seasons especially in winter
Smokers
Passive smoking
Recent influenza A
Immunodeficiency
Abnormal Spleen function
Living in 'closed' communities e.g. halls of residence
Age

Question 8

Which meningococcal disease is worst?

Answer 8

Meningococcal sepsis

Question 9

What causes the rash in meningococcal disease

Answer 9

Severe infection disrupts the body’s usual clotting cascade
Abnormal bleeding occurs in some parts of the body
In other blood vessels, clotting of the blood blocks flow of blood

Question 10

Rashes

Answer 10

Purpuric rash

Petechial rash

Question 11

Meningcoccal meningitis

Answer 11

Meninges around the brain are infected, damaging the blood vessels in the lining of brain. Allows bacteria to leak into and infect the cerebrospinal fluid. The meninges become inflamed and pressure around the brain is increased.

Question 12

Meningococcal disease is a…

Answer 12

notifiable disease