Mendelian Inheritance

Question 1

Autosomal dominant

Answer 1

Dominant; each child has a 50% chance of inheriting the mutation, there are no skipped generations as you only need one mutated gene. Equally transmitted by men and women. Male to male transmission.

Question 2

X-Linked

Answer 2

Generally only effects males due to only one X chromosome. Women can be carriers as 2 X chromosomes present. Can skip generations with no male to male transmission.

Question 3

Autosomal recessive

Answer 3

Recessive; two copies of an abnormal gene must be present in order for the disease/trait to develop. Carrier state possible. 2 carrier parents; 25% chance of disorder or normality and 50% chance of a carrier child.