Mendelian Genetics Flashcards

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1
Q

What are the 5 reasons why the garden pea plant was an ideal organism for Mendels experiments?

A
  • Easy to grow
  • Short life cycle
  • Large # of progeny
  • Self-fertilizers
  • Easy to cross-fertilize
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2
Q

How many different traits were individually analyzed during the pea plant experiments?

A

7

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3
Q

What are the 5 reasons mendels experiments were so successful?

A
  1. The garden pea is an ideal organism
  2. Traits were analyzed individually
  3. Pure-breeding lines were etablished (always same trait made)
  4. Reciprocal crosses performed (male purple x female white) and (male white x female purple)
  5. Performed statistical analyses to provide accurate conclusions
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4
Q

What is the law of segregation?

A

During gamete formation, each each pair of genes separate randomly so each gamete receives either with equal likelihood.

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5
Q

What is a test cross?

A

crossing unknown genotype w/ homozygous recessive to reveal genotype.

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6
Q

What is the definition of a dihybrid cross?

A

A cross between 2 hybrids differing in 2 traits.

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7
Q

What is the law of independent assortment?

A

Genes on different, nonhomologous chromosomes separate independently of one another during meiosis.

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8
Q

what is the binomial expansion equation and what are each of the variables related to?

A

P= n! / x! (n - x)! * p^x * q^n-x

n - total # of events
! - factorial
x - # of events one category
q - probability one category
p - probability other category
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9
Q

Describe the process for performing the Chi-Square (X^2) Test. what is a null hypothesis? What does the p value indicate?

A
  1. Null hypothesis - No significant difference between expected and observed results.
  2. List each phenotype and # of observed
  3. calculate number of expected for each phenotype
  4. Perform X^2 analysis: [(observed - expected)^2 / expected
  5. determine degrees of freedom (df): N - 1 (N= # of classes)
  6. Find the p-value using df and X^2 value.

The P value indicates how accurate the null hypothesis is. if its greater than 0.05, there is greater than 5% chance that the null is accepted and the deviation is likely due to chance.

If the p-value is less than 0.05, it is less than 5% likely that the deviation is due to random chance. Therefore the null hypothesis can be objected.

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