MEN

Question 1

what does MEN stand for ?

Answer 1

multiple endocrine neoplasia

Question 2

what three tumours does MEN1 have ?

Answer 2

Pituitary adenoma: prolactin or GH
􏰀 Parathyroid adenoma / hyperplasia
􏰀 Pancreatic tumours: gastrinoma or insulinoma

Question 3

what is marfanoid habitus?

Answer 3

symptoms resembling those of Marfan syndrome, including long limbs, with an arm span that exceeds the height of the individual, and a crowded oral maxilla, sometimes with a high arch in the palate, arachnodactyly, and hyperlaxity.

Question 4

what are the features of MEN2?

Answer 4

Thyroid medullary carcinoma 􏰀 Adrenal phaeochromocytoma
􏰁 A) Hyperthyroidism 􏰁
B) Marfanoid habitus

Question 5

what are the features of LAMES syndrome?

Answer 5

Lentigenes: spotty skin pigmentation
􏰁 (Differential: Peutz-Jehgers)

Atrial Myxoma

􏰀 Endocrine tumours: pituitary, adrenal hyperplasia 􏰀

Schwannomas

Question 6

what are the features of neurofibrimatosis ?

Answer 6

Dermal neurofibromas 􏰀 
Café-au-lait spots
􏰀 Lisch nodules
􏰀 Axillary freckling
􏰀 Phaeochromocytoma

Question 7

what are the three features of autoimmune polyendocrine syndrome type 1 ?

Answer 7

Addison’s
􏰀 Candidiasis
􏰀 Hypoparathyroidism

Question 8

what are the three features of autoimmune polyendocrine syndrome type 2 (Schmidts syndrome) ?

Answer 8

Addison’s

􏰀Thyroid disease: hypothyroidism or Graves’ 􏰀 T1DM