Membranes And Transport🚧 Flashcards
Functions of the plasma menbrane
- To give the cell structure
- To allow substances to exit and enter the cell
- Cell-to-cell recognition and cell-to-cell signalling
Features of a phospholipid bilayer
- Phospholipid - hydrophilic phosphate head and hydrophobic fatty acid tail
- Intrinsic and extrinsic proteins
- Cholesterol
- Glycolipids
- Glycoproteins
- Carbohydrate chains
What is the importance of the arrangement of the phospholipid molecules?
- The hydrophilic heads face out
- The hydrophobic tails face in
- This forms a hydrophobic, non-polar region in the middle
- This prevents polar molecules such as glucose from passing through
Polar
Uneven distribution of charge
Non polar
No charge
Ion
Charged particle
What is the width of the membrane under the electron microscope?
7 nm
Intrinsic proteins
Lie across both layers of the membrane.
Transport substances.
Channel or carrier protein.
Extrinsic proteins
In one layer of the membrane or in the surface.
Hormone receptors, cell recognition, enzymes.
What does a receptor protein do?
Recognises and binds with specific molecules outside the cells.
What does a glycoprotein do?
A protein with a carbohydrate attached.
Involved in cell signalling, cell recognition and binding cells together.
Some act as antigens.
What does a glycolipid do?
Lipids with a carbohydrate chain attached.
Involved in cell signalling and cell recognition.
What does a carrier protein do?
Transports larger polar molecules such as sugars and amino acids.
The molecule attaches at the binding site to a particular carrier protein and the protein changes shape to deliver the molecule.
What does a channel protein do?
Opens up pores across the membrane which are lined with polar groups. This allows charged ions to pass through.
Usually, each channel is specific.
What does the fluid mosaic model mean?
- Fluid - all parts of the membrane can move relative to each other.
- Mosaic - the proteins are dotted throughout the membrane.
Cholesterol
Can fit between the molecules.
Increases rigidity and stability of the membrane.
What affects membrane permeability?
- Low temperature
- High temperature
- Organic solvents
How does a low temperature affect permeability?
Fatty acids become compressed and so the membrane becomes less dynamic.
This decreases permeability.
How does a high temperature affect permeability?
The phospholipids acquire energy and move randomly and at a faster rate.
This increases membrane fluidity, and therefore the permeability.
How do organic solvents such as ethanol affect permeability?
Organic solvents such as ethanol can be used to dissolve the phospholipids and so increase the permeability.
What affects the rate of transport of molecules?
- Concentration gradient
- Particle size
- Thickness of membranes
- Surface area
- Distance
- Temperature