Membrane structure

Question 1

Which structures make up the nucleus?

Answer 1

• Chromatin
• nuclear envelope
• nuclear pore
• nucleolus

Question 2

difference between cytosol and cytoplasm

Answer 2

• Cytosol is the fluid where the other elements of cytoplasm remain suspended.
• cytoplasm includes all components that can be found inside the cell membrane(apart from nucleus). Cytoplasm contains cytosol, along with the organelles

Question 3

What are the lipids in cellular membranes?

Answer 3

• cholesterol
• glycolipids
• phosphatidylcholine
• sphingomyelin
• phosphatidylethnolamine
• phosphatidylinositol
• phosphatidylserine
• phosphatic acid
• phosphatidylglyerol

Question 4

Organelles surrounded by lipid membranes

Answer 4

• nucleus, mitochondria and chloroplasts

- double lipid bilayers consisting of inner and outer membranes

Question 5

Types of proteins in the plasma membrane

Answer 5

-transmembrane (integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached)
-membrane associated
-lipid linked
-protein attached
-protein channels
-peripheral protein
-surface protein
-globular/integral protein (don’t penetrate in membrane but are associated with membrane)
-alpha helix protein
LOOK AT DIAGRAM

Question 6

What do proteins represent in a pharmacy context?

Answer 6

• they represent drug targets

- act as receptors and channels

Question 7

Main lipids in cellular membrane

Answer 7

• phospholipid (hydrophilic head -phosphate- and hydrophobic region -fatty acid tail-)
• cholesterol (the rigid steroid region points up because it’s polar and the non-polar hydrocarbon tail is orientated in the membrane)