Membrane modelling and ionic balance Flashcards
What is electrophysiology?
the study of electrical properties of biological cells and tissue
What are surface electrodes?
Measurements to record field potentials, e.g ECG, EEC, EMG
What is membrane potential?
the relative distribution of ions across a cell membrane and the relative permeability of the membrane to the movement of ions
Charge of the inside of the cell
Negative
Charge of the outside of the cell
Positive
How are ion channels variable resistors?
They can be opened and closed by different variables
Voltage gated channels
Opens in a difference of voltage charges
Ligand gated
Acteylcholine
Mechanosensitive
movement
What are the other pathways for ions?
Other electrogenic proteins e.g. primary active transporters and secondary active transporters
Are ion channels and transporters the same?
NO.
The movement of ion channels are…
passive
The movement of active transporters are…
active
Like ion channels, some transporters can also…
generate a current
Are all action potentials the same?
Yes and no, they are only the same in their respective cells. Each action potential is distinct from one another depending on the cell it was recorded from.
