Melanocytic Neoplasm and Pigmented Lesions Flashcards
3 types of benign (non-cancerous) pigmented lesions?
- Seborrheic keratosis
- Cafe-au-lait macules
- Dermatofibroma
What are seborrheic keratosis?
Keratinocytic proliferation with horn cyst
Dermoscopy: comedo-like opening and cerebriform ridges
What are Cafe-au-lait macules?
Uniformed pigmented macules due to neurofibromatosis if multiple
What are Dermatofibroma?
Firm, dermal lesion showing dimple sign
Dermoscopy: central white scar like area with peripheral pigment network
2 types of benign (non-cancerous) melanocytic lesions?
- Benign Melanocytic nevi
- Blue nevus
What is benign melanocytic nevi?
Acquired or congential melanocytic proliferation (follow an age dependent evolution; junctional>compound>dermal)
What is Blue nevus?
Dermal melanocytic proliferating. Colour is produced by Tynall effect (gives the blue hue)
5 types of Malignant Melanoma?
- Superficial spreading melanoma (SSM)
- Nodular melanoma (NM)
- Lentigo maligma melanoma (LMM)
- Acral lentiginous melanoma (ALM)
- Desmoplastic melanoma (DM)
What is Superficial spreading melanoma (SSM)?
Radial growth phase-dominant melanoma/
Asymmetry, colour variegation (different colour zones) and irregular network
What is Nodular melanoma (NM)?
Rapid growth lesions. Vertical growth predominance and raised, lacks radial spread
What is Lentigo maligma melanoma (LMM)?
Arise from chronic sun damage.
Dermoscopy: follicular obliteration (loss/destruction of hair follicles) and rhomboidal structure (Thick pigmented lines around appendageal openings)
What is Acral lentiginous melanoma (ALM)?
Location: Palm, sole and subungual regions (under nail)
dermoscopy: parallel ridge pattern
What is Desmoplastic melanoma (DM)?
Amelanotic (lacks the typical dark pigment; skin coloured. pink, reddish), fibrotic with perineural invasion
