Meiosis and Genetic Variation Flashcards

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1
Q

Why is meiosis important

A

In sexual production 2 gametes fuse to give rise to the new off spring. If each gamete had a full set of chromosomes ( diploid number) then the cell that they produce has double this number.

In order to maintain a constant number of chromosomes in the adults of a species, the number of chromosomes must be halved at some age in the life cycle. This Halving occurs as a result of meiosis

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2
Q

What happens to the diploid cell of an organism that has two complete sets of chromosomes, one set provided by each parent?

A

During meiosis, homologous pairs of chromosomes separate so that only one chromosome from each pair enters a daughter cell. This is known as the haploid number of chromosomes (23 in humans ).

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3
Q

What happens when two haploid gametes dude at fertilisation

A

The diploid number of chromosomes is restored

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4
Q

How does meiosis bring about genetic variation (2 ways)

A

Independent segregation of homologous chromosomes

New combinations of maternal and paternal alleles by crossing over

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5
Q

What’s a gene

A

A length of dna that codes for a polypeptide

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6
Q

What’s a locus

A

The position of a gene on a chromosome or dna molecule

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7
Q

What’s an allele

A

One of the different forms of a particular gene

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8
Q

What’s a homologous chromosomes

A

A pair of chromosomes, one Maternal and one paternal, that have the same gene loci

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9
Q

What’s independent segregation of chromosomes

A

Each homologous pair of chromosomes in your cells is made up of one chromosome from your mum and one chromosome from your dad

When the homologous pairs are separated in meiosis 1, it’s completely random which chromosome from each pairs ends up in which daughter cell

So the 4 daughter cells produced by meiosis have completely different combinations of those Maternal and paternal chromosomes

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10
Q

How does crossing over of the Chromatids cause genetic variation

A

The Chromatids of each pair become twisted around one another

During this twisting process tensions are created and portions of the Chromatids break off

These broken portions might then rejoin with the Chromatids of its homologous partner

Usually it is equivalent portions of homologous chromosomes that are exchanged

In this way new genetic combinations of Maternal and paternal alleles are produced

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11
Q

What is recombination

A

When the broken off portions of Chromatids recombine with another chromatid

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12
Q

What’s the formula to determine the number of possible combinations of chromosomes for each daughter cell

A

2 to the power of n

N=the number of pairs of homologous pairs

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13
Q

Formula used to determine number of possible chromosome combinations in zygotes due to random fertilization.

A

2 to the nth power all squared.

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14
Q

What happens during crossing over

A

Pairing up homologous chromosomes (synapsis) to form a bivalent

Cross over region is the chiasma

Equal sections of non sister Chromatids are exchanged between Maternal and paternal chromosomes ( recombination); creating new combinations of alleles

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15
Q

what does non disjunction mean

A

it is the failure of homologous chromosomes or sister chromatids to separate properly during cell division

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16
Q

why independent assortment/ segregation important

A

Genetic variation

Because homologous chromosomes pairs arrange randomly at
equator/middle of cell

So different combinations of maternal and paternal chromosomes
and the alleles they possess are passed into daughter cells
(maternal and paternal chromosomes are shuffled);

17
Q

describe meiosis 1

A

Prophase I: DNA coils to form chromosomes, nucleus breaksdown, spindle fibres form. crossing over occurs

Metaphase I: homologous pair of chromosomes line up in middle of cell and attach to spindle fibre via centromere by random assortment

Anaphase I: spindle fibres pull, homologous pair of chromosomes separate to opposite sides by independent segregation

Telophase I: chromosomes uncoil, nucleus reforms (left with 2 nuclei)

18
Q

describe meiosis II

A

Prophase II: DNA coils to form chromosomes, nucleus breaksdown, spindle fibres form

Metaphase II: chromosomes line up in middle of cell and attach to spindle fibre via centromere by random assortment

Anaphase II: spindle fibres pull, centromere splits, sister chromatids move to opposite sides by independent segregation

Telophase II: chromatids uncoil, nucleus reforms (left with 4 genetically different nuclei)

19
Q

what happens during cytokinesis

A

separating cell into 4 (each receives a nucleus and organelles/cytoplasm)

20
Q

What happens to DNA mass in meiosis?

A

quarters

21
Q

What happens to Chromosome number in meiosis?

A

halves