Meiosis Flashcards
prophase 1
homologous chromosomes pair up and exchange fragments(crossing over)
Metaphase 1
homologous pairs line up at the metaphase plate
Anaphase 1
Homologues separate to opposite ends of the cell. Sister chromatids stay together
Telophase 1
Newly forming cells are are haploid (n=2)
When does crossing over occur
crossing over occurs at prophase 1
What is chiasma
the middle of the chromosome
The aim of meiosis
creating 4 gene
Three mechanisms by which meiosis promotes genetic variation
- Crossing over between non-sister chromatids during prophase 1
- random assortment of homologous chromosomes during metaphase 1
- fusion of gametes from different parents
Why do we want genetic variation
Allows us to improve survival rate
- increases biodiversity
What is a chromosome called after crossing over
Bivalent
How many different chromosome combinations do gametes have
2^23
Which chromosome is affected when downsyndrome accurs?
21st chromosome
Two phases of non-dysjunction
- Homologous pairs in anaphase 1 (all four daughter cells will be affected)
- sister chromatods chromatids in anaphase 11 (only two of the daughter cells affected)
Factor of downsyndrome occuring more frequently?
Increasing age
What is karyotiping:
The image of 23 pairs of chromosomes
- chorionic villi sampling where cells are taken from the placenta
- Amniocentesis cells from amniotic fluid
Issue with chorionic villi sampling where cells are taken
higher risk of miscarriage
Whats good about Amniocentesis cells from amniotic fluid
lower risk of miscarriage