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Hematology 2 (Prelim) > Megakaryopoiesis > Flashcards

Megakaryopoiesis Flashcards

Stages , Platelet Structure , Henostasis

1
Q

Proceeds initially through a phase chracterized by mitotic division of a progenitor cell.

A

Megakaryopoiesis

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2
Q

Maturation of megakaryocyte is through.

A

Endomitosis

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3
Q

Earliest recognizable stage

A

Megakaryocyte

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4
Q

Cytoplasm has aggregates of granular material into masses seperated by DMS

A

Metamegakaryocyte

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5
Q

At least 4 nuclei can produce platelets

A

Megakaryocytes

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6
Q

Contains mithochondria and primitive endoplasmic reticulum

A

Megakaryoblast

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7
Q

Has a diameter of 15 - 50 um

A

Megakaryoblast

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8
Q

Function as the future membrane system of platelets

A

DMS

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9
Q

Abundant cytoplasm contains numerous small granules with a reddish blue hue

A

Megakaryocyte

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10
Q

A very large cell

A

Metamegakaryocyte

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11
Q

Size is larger to megakryoblast

A

Promegarkaryocyte

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12
Q

Nucleus is multilobed and ploidy ranges from 4N to 64N

A

Metamegakaryocyte

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13
Q

Decreased nuclear cytoplasmic ratio

A

Metamegakaryocyte

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14
Q

Cytoplasm is devoid of specific organelles

A

Megakaryocyte

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15
Q

Nucleus usually undergone one or two division

A

Promegakaryocyte

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16
Q

Contain single, centrally located nucleus or multiple round and oval nuclei with nucleoli

A

Megakaryoblast

17
Q

Bluish stained granules

A

Promegakaryocyte

18
Q

Abundant cytoplasm contain numerous small granules with reddish blue hue

A

Megakaryocyte

19
Q

Platelet structure

A
  1. Peripheral zone
  2. Submembrane Area
  3. Sol gel zone
  4. Organelle Zone
20
Q

Act as open communication channels into the platelet cytoplasm

A

Glycocalynx

21
Q

Contains Glycoproteins

Thickness 10 - 50nm

A

Glycocalyx

22
Q

Physical and chemical barrier

A

Plasma membrane

23
Q

Contain structure to prevent contact between organelles and the cell membrane.

A

Submembrane area

24
Q

Contribute to the regulation of normal platelet doscoid shape

A

Microfilaments

25
Q

Contribute to the regulation of normal platelet doscoid shape

A

Microfilaments

26
Q

Serve as table gel

A

Sol gel zone

Hematology 2 (Prelim) (1 decks)

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