Meds--GI

Question 1

Meds to Tx: Heartburn/GERD

Answer 1

Antacids
Antisecretory/Blocking agents (?)
PPI
H2 Receptor antagonists
Mucosal protectants

Question 2

Antacids–Types, S/E, Nx considerations, Contraindications

Answer 2

(aluminum hydroxide)–only one OK for renal pts, S/E: constipation
(magnesium hydroxide = MOM)–Nx: monitor hyperMg2+, S/E: dirrhea
(sodium bicarbonate)–S/E: constipation
Nx: avoid all other meds by 1 hr
Contra: GI perf/bowel obstruct

Question 3

PPI–S/E

Answer 3

(omeprazole)

S/E: increased risk infect/fractures/pneu/Ac rebound

Question 4

H2 receptor antagonists–S/E

Answer 4

(cimetidine)

S/E: increased risk infect/pneu, impotence

Question 5

Mucosal protectants–Nx considerations

Answer 5

(sucralfate)

Nx: empty stomach 1 hr b4 meals, works 6 hrs

Question 6

Meds to Tx: Nausea

Answer 6

antiemetics--S/E: EPSs
(promethazine)
(metoclopramide = Reglan)--increases peristalsis
(ondansetron)
(scopolamine)

Question 7

Meds to Tx: Diarrhea

Answer 7

Funct: activate opioid receptors in GI to decrease motility
(diphenoxylate plus atropine = Lomotil)
(loperimide)
(psyllium)–bulk-forming

Question 8

Meds to Tx: Constipation

Answer 8

(psyllium)--bulk-forming to decrease diarrhea
(docusate sodium)
(bisacodyl)
(magnesium hydroxide = MOM)
Contra: fecal impaction/bowl obstruct