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EOR - Behavioral Med > Meds > Flashcards

Meds Flashcards

1
Q

SSRI drug list

A 
Fluoxetine (Prozac) 
Sertraline (Zoloft) 
Escitalopram (Lexapro) 
Fluvoxamine (Luvox)
Paroxetine (Paxil)
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2
Q

What are the SE of SSRIs in general?

A

sexual dysfunction, decrease libido, prolonged ejactulation
affect platelet function (makes them slippery)
Risk of serotonin syndrome

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3
Q

Serotonin syndrome

A

shivering, hyperreflexia, myoclonus, ataxia, N/V/D

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4
Q

Long-Acting Benzos

A

Chlordiazepoxide (Librium)
Clorazepate (Tranxene)
Diazepam (Valium)
Flurazepam (dalmane)

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5
Q

Intermediate acting Benzos

A

Alprazolam (Xanax)
Clonazepam (Klonopin)
Lorazepam (Ativan)
Temazepam (Restoril)

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6
Q

What receptor does Buspar act on?

A

5HT partial agonist

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7
Q

What is Buspar used for?

A

useful in alcoholics

low addiction potential (good for those addicted to benzos)

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8
Q

Typical Antipsychotic list

A 
Haloperidol (Haldol) 
Fluphenazine (Prolixin) 
Perphenazine (Trilafon) 
Thioridazine (Mellaril) 
Chlorpromazine (Thorazine)

Class overall SE: EPS

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9
Q

Atpyical Antipsychotic List

A 
Aripiprazole (Abilify) 
Asenapine (Saphris) 
Olanzapine (Zyprexa) 
Quetiapine (Seroquel) 
Risperidone (Risperdal) 
Clozapine (Clozaril) 
Lurasidone (Latuda)

Overall class SE: weight gain, DM

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10
Q

Dopamine antagonists

A

antipsychotic effect
relief of + sxs of schizophrenia
increase EPS
increase prolactin

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11
Q

Serotonin 1A agonists

A

antidepressants

anxiolytic effects

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12
Q

Serotonin 2A antagonist

A

improvement of neg sxs of schizophrenia and improved cognition

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13
Q

Serotonin 2X antagonists

A

weight gain and associated risks

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14
Q

Fluoxetine

A

prozac
SSRI

lowest weight gain - good for ED pts
most stimulating SSRI
longest half life

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15
Q

Citalopram

A

Celexa

SSRI

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16
Q

Escitalopram

A

Lexapro

SSRI

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17
Q

Fluvoxamine

A

Luvox

SSRI

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18
Q

Sertraline

A

Zoloft
SSRI

highest risk of GI problems

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19
Q

Paroxetine

A

Paxil
SSRI

most sedating SSRI and greatest weight gain and sexual SE
shortest half life

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20
Q

As a class, what are the SE of SSRIs in general?

A

GI, CNS, sexual dysfunction, fatigue, dry mouth, hypotension, withdrawal if d/c abruptly, prolonged QT, rash, insomnia, asthenia, seizure, tremor, somnolence, mania, SI, worsened depression
risk of Serotonin syndrome

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21
Q

Venlafaxine

A

Effexor
SNRI

SE: HTN, sedating

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22
Q

Duloxetine

A

Cymbalta
SNRI

less SE than venlafazine
works well for fibromylagia, sleep, and pain

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23
Q

Desvenlafaxine

A

Pristiq

SNRI

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24
Q

As a class, what are the SE of SNRIs in general?

A

equally effective as SSRIs in treating major depression
may be more effective in the setting of diabetic neuropathy, fibromyalgia, msk pain, stress incontinence, sedation, fatigue, and pts with comorbid anxiety

SE: GI, HTN, CNS, diaphoresis, dizziness, fatigue, insomnia, blurred vision, suicidal idea

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25
Bupropion
Wellbutrin atypical antidepressant may increase sexual function has stimulant effects helps with smoking cessation NOT to be used in eating disorder pts ``` SE: lower seizure threshold insomnia nervousness agitation anxiety tremor weight loss suicidal ideation ```
26
Mirtazapine
Remeron atypical antidepressant the most sedating antidepressant - good for insomnia
27
Trazodone
Oleptro | atypical antidepressant
28
Amitryptyline
Elavil | tricyclic antidepressants
29
Clomipramine
Anafranil tricyclic antidepressant only FDA OCD tx
30
Desipramine
norpramin | tricyclic antidepressant
31
Doxepin
Silenor | tricyclic anitdpressant
32
Impiramine
Tofranil | tricycylic antidepressant
33
Nortriptyline
Pamelor | tricyclic antidepressant
34
What are the side effects in general for the class of tricyclic antidepressants?
anticholinergic CV, CNS, weight gain, sexual dysfunction, decreased seizure threshold cardiotoxicity
35
MOA of MAOIs
block destruction of monoamines both centrally and peripherally
36
MOA of TCA
inhibit reuptake of both serotonin and NE (like SNRI)
37
MOA of SNRI
inhibit reuptake of both serotonin and NE (like TCA)
38
Phenelzine
Nardil MAOI irreversible
39
Tranylcypromine
Parnate MAOI irreversible
40
Selegiline
Emsam MAOI reversible
41
Carbamazepine
tegretol mood stabilizer MOA: inhibits voltage gated Na channels CI: pregnancy decrease effectiveness of warfarin and OCPs SE: diplopia, dizziness, drowsiness, nausea, SJS (don't use in Asians) SIADH, hypoCa/Na
42
Valproate
Depakote/Depakene mood stabilizer MOA: increases GABA SE: GI upset, sedation, unsteadiness, tremor, thombocytopenia, palpitations, ototoxic CI: pregnancy, liver disease
43
Lamotrigine
Lamictal mood stabilizer MOA: block voltage gated Na channels, inhibit glutamate release SE: hematologic, liver failure
44
What are the side effects of TCA?
``` anticholinergic effects lead to: blurry vision constipation urinary retention dry mouth ```
45
What are the side effects of typical antipsychotics?
``` EPS Hyperporlactinemia Tardive dyskinesia NMS rare: agranulocytosis (low potency typical antipsychotics) ```
46
What meds put you at risk for Tardive dyskinesia?
typical antipsychotics - 5% risk each year | clozapine (the first atypical antipsychotic - less likely to cause tardive dyskinesia)
47
NMS
possible side effect of typical antipsychotics medical emergency - 20% mortality rate if left untreated ``` Fever Autonomic instability (tachycardia, labile HTN, diaphoresis) Leukocytosis tremor Elevated CPK Rigidity (lead pipe) Delirium (AMS) ```
48
What is the treatment for NSM?
dantrolene, bromocriptine, amantadine
49
Typical vs atypical antipsychotics
typical: DA receptor antagonist atypical DA + 5HT receptor antagonist atypical less likely to cause EPS, TD, or NMS atypicals have risk of metabolic syndrome
50
What is the risk of using Lithium while pregnant?
Ebstein's anomaly in the unborn fetus
51
What levels must be monitored when a pt is on cloazpine?
atypical antipsychotic | must monitor WBC every week for first 6 months dt risk of agranulocytosis
52
What levels must be monitored when a pt is on lithium?
lithium levels thyroid funciton Cr - d/t being metabolized by the kidneys should be checked 5 days after start of drug and then every 2-3 days until therapeutic (therapeutic range is 0.6-1.2) there is a risk of increasing the lithium levels in the blood to possibly toxic levels (>1.5) if the pt is on NSAIDs, ASA or gets dehydrated
53
What is the MOA of carbamazepine?
tegretol - anticonvulsant that is used as a mood stabilizer blocs sodium channels - inhibits action potentials
54
What are the SE of carbamazepine?
GI and CNS (drowsiness, ataxia, sedation, confusion) | Teratogenic - neural tube defects
55
What is the MOA of Depakote?
valproate blocks sodium channels and increases [GABA] in the brain
56
Fluoxetine
Prozac - SSRI
57
Sertraline
Zoloft - SSRI
58
Paroxetine
Paxil - SSRI
59
Fluvoxamine
Luvox - SSRI
60
Citalopram
Celexa - SSRI
61
Escitalopram
Lexapro - SSRI
62
Venalfaxine
Effexor - SNRI
63
Desvenlafazine
Pristiq - SNRI
64
Duloxetine
Cymbalta - SNRI
65
Bupropion
Wellbutrin - NE-DA Reuptake inhibitor
66
Trazodone
Desyrel - 5HT Receptor Modulator
67
Nefazodone
Serzone - 5HT receptor modulator
68
Mirtazapine
Remeron - alpha 2 antagonist/5HT antagonist --histaminigeric (sleepy + fat) sedation + weight gain tx for AN
69
Imipramine
Rofranil - TCA
70
Selegiline
Emsam - MAOI
71
Chlorpromazine
Thorazine - first gen antipsychotic
72
Thioridazine
mellaril - first gen antipsych
73
Loxapine
Loxitane - first gen antipsych
74
Thiothizene
Navane - first gen antipsych
75
Molindone
Moban - first gen antipsych
76
Perphenazine
Trilafon - first gen antipsych
77
Haloperidol
Haldol - first gen antipsych
78
Fluphenazine
Prolixin - first gen antipsych
79
Trifluoperazine
Stelazine - first gen antipsych
80
Pimozide
Orap - first gen antipsych
81
Clozapine
Clozaril - second gen anitpsych
82
Risperidone
Risperdal - second gen antipsych
83
Quetiapine
Seroquel - second gen antipsych
84
Olanzapine
Zyprexa - second gen antipsych
85
Ziprasidone
Geodon - second gen antipsych
86
Aripiprazole
Abilify - second gen antipsych
87
Lurasidone
Latuda - second gen antipsych
88
Anticonvulsants used for mood
``` Carbamazepine (tegretol) Valproate (Depakote) Lamotrigine (Lamictal) Oxcarbazepine (trileptal) Gabapentin (neurontin) Pregabalin (lyrica) Topiramate (Topamax) ```
89
Klonipin
clonazepam - benzo

EOR - Behavioral Med (2 decks)

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