Meds Flashcards
Protein targeted therapy
TKIs, mTOR inhibitor, proteasome inhibitor
Rash, hand/foot, sutent-hair depigmentation
Cardio toxicity
GI- n,v,d, dec appetite
Angiogenesis inhibitors
VEGF-Bevacizumab/avastin
Immuno-modulatory-inhibit pro-inflamm cytokines
lenalidomide/revlimid
Thalidomide
Htn, thrombo embolitic events, proteinuria, bleeding, hypothyroiD
GI perf-n,v,c,fever
Monoclonal antibodies
Rituximab/Rituxan
Trastuzumab/herceptin
Infusion rxn, cardiotoxicity, myelosupp, pulm fox, rash, hand/foot
TKIs
Erlotinib/tarceva
Imatinib/gleevec
Sorafenib/nexavar
Sunitinib/sutent (hair depigment)
mTOR inhibitors
Temsirolimus/torisel
Everolimus/affinitor
(Block VEGF, PDGF)
Proteasome inhibitor
Bortezomib/velcade
Bendamustine/treanda
N,v, fatigue
Myelosupp
Infusion rxn
Tumor lysis
Busulfan/myleran
N,v,d,mucositis
Myelosupp
Hepatic tox
Adrenal insufficiency
Carboplatin/paraplatin
N, v
Myelosupp
Renal toxicity
Mild periph neurop
Carmustine (BCNU)
N, v Myelosupp Hepatic Renal Pulm toxicities
Chlorambucil/leukeran
N, v
Hyperuricemia
Pulm tox
Cisplat/platinol/CDDP
N, v (acute and delayed) Myelosupp Renal tox Hypomag SIADH Ototoxicity
Infusion rxn
Peripheral neuropathy
Cyclophosphamide/cytoxan/CTX
N,v Myelosupp Bladder Cardiac SIADH
Dacarbazine/DTIC
N,v Myelosupp Flu like sx CNS tox Photosensiviry
Ifosfamide/ifex
N, v, anorexia Myelosupp Bladder tox SIADH Neuro tox
*mesna