Meds Flashcards

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1
Q

meds for NCD (4)

A
  • cholinesterase inhibitors
  • NMDA receptor agonists
  • antipsychotics
  • benzodiazepines
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2
Q

antipsychotics for NCD (3)

A
  • Risperidone (Risperdal)
  • Olanzapine (Zyprexa)
  • Haloperidol (Haldol)
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3
Q

examples of benzodiazepines (2)

A
  • Clonazepam (Klonipin)

- Lorazepam (Ativan)

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4
Q

FGA example

A

Haloperidol (Haldol)

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5
Q

SGA examples (5)

A
  • Aripiprazole (Abilify)
  • Risperidone (Risperdal)
  • Olanzapine (Zyprexa)
  • Quetiapine (Seroquel)
  • Clozapine (Clozaril)
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6
Q

Clozapine

A
  • trade: Clozaril
  • first effective antipsychotic (SGA) with low EPS
  • reserved for patients who have failed standard therapies because of side effects
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7
Q

Clozapine side effects (2)

A
  • agranulocytosis

- risk for myocarditis

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8
Q

antipsychotics indication (4)

A
  • MAIN: schizophrenia/psychosis
  • adjunctive treatment for bipolar (or benzodiazepines)
  • NCD/delirium
  • ASD
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9
Q

FGA side effects (4)

A
  • extrapyramidal symptoms
  • tardive dyskinesia
  • neuroleptic malignant syndrome
  • orthostatic hypotension
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10
Q

SGA side effects (5)

A
  • weight gain
  • dyslipidemia
  • type 2 diabetes
  • accelerated CVD
  • metabolic syndrome
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11
Q

metabolic syndrome symptoms (5)

A
  • abdominal obesity
  • high triglyceride level
  • low HDL cholesterol level
  • hypertension
  • elevated blood glucose level
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12
Q

medications to counteract EPS (2)

A
  • Benztropine (Cogentin)

- Amantadine (Symmetrel)

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13
Q

antipsychotics for ASD (2)

A
  • Risperidone (Risperdal)
  • Aripiprazole (Abilify)

these are the ONLY FDA apporved agents for ASD

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14
Q

how long does it take for antipsychotics to take effect?

A

1-2 weeks

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15
Q

examples of SSRIs

A
  • Fluoxetine (Prozac)

- Sertraline (Zoloft)

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16
Q

how long does it take for SSRIs to take effect?

A

4-6 weeks

17
Q

how long should you take antidepressants for?

A

6-12 months

18
Q

SSRI side effects (6)

A
  • headache
  • nausea – serotonin receptors in our gut
  • insomnia/anxiety
  • weight gain/loss
  • sexual dysfunction
  • serotonin syndrome
19
Q

serotonin syndrome

A
  • rare but life-threatening side effect of SSRIs
  • most often caused by drug-drug interaction
  • treat by removing agent and administering meds that block serotonin receptors
20
Q

serotonin syndrome side effects

A

diarrhea, restlessness, agitation, hyperreflexia, autonomic instability, myoclonus, seizures, delirium, coma, status epilepticus, cardiovascular collapse

21
Q

types of antidepressants (5)

A
  • selective serotonin reuptake inhibitors (SSRIs)
  • serotonin-norepinephrine reuptake inhibitors (SNRIs)
  • tricyclics
  • monoamine oxidase inhibitors (MAOIs)
  • heterocyclics
22
Q

how long does it take for mood stabilizers/anticonvulsants to take effect?

A

1-3 weeks

23
Q

pharmacologic treatment for bipolar disorder

A

mood stabilizers + adjunctive treatment with antipsychotics/benzodiazepines until symptoms resolve

24
Q

lithium

A
  • trade: Eskalith, Lithobid
  • only true mood stabilizer
  • has narrow therapeutic range
25
Q

lithium therapeutic range

A
  • acute mania: 1.0-1.5 mEq/L

- maintenance: 0.6-1.2 mEq/L

26
Q

lithium side effects (8)

A
  • drowsiness, dizziness, headache
  • dry mouth, thirst, dehydration
  • GI upset, nausea/vomiting
  • fine hand tremors
  • polyuria
  • weight gain
  • acne
  • lithium toxicity
27
Q

lithium toxicity can cause (5):

A
  • renal impairment
  • nephrogenic diabetes insipidus
  • hypotension
  • arrhythmias
  • pulse irregularities
28
Q

examples of anticonvulsants (3)

A
  • Valproic acid (Depakene, Depakote)
  • Lamotrigine (Lamictil)
  • Carbamazepine (Tegretol)
29
Q

Valproic acid side effects (5)

A
  • sedation
  • weight gain
  • hepatotoxicity with liver failure
  • pancreatitis
  • prolonged bleeding time
30
Q

Lamotrigine side effect

A

Steven Johnson’s Syndrome – disorder of skin and membranes; rash, burn-like

31
Q

Carbamazepine side effects (3)

A
  • Stevens Johnson’s Syndrome
  • aplastic anemia
  • hyponatremia
32
Q

antipsychotics for bipolar disorder (3)

A
  • Olanzapine (Zyprexa)
  • Quetiapine (Seroquel)
  • Risperdone (Risperdal)
33
Q

benzodiazepines indications (3)

A
  • adjunctive treatment for bipolar (or antipsychotics)
  • NCD/delirium
  • given with IM antipsychotics for schizophrenia
34
Q

examples of stimulants (3)

A
  • Methylphenidate (Ritalin, Concerta)
  • Amphetamine (Adderall)
  • Lisdexamfetamine (Vyvanse)