- Decreases BP - Increases peripheral blood flow and walking distance - Decreases workload of the heart, preventing remodeling (hypertrophy and cardiomyopathy)

Meds Flashcards by Ju Hodge

Allopurinol MOA

Decrease uric acid

Prevents renal damage r/t chemo bc cells die and the break down of DNA releases Uric acid

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Allopurinol SE/labs

When to stop

Nephrotoxic
Monitor Uric acid
STOP: rash or fever

Se: metallic taste, cataracts

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Atenolol indication

Raynauds
Dysrhythmias
HTN

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Atenolol MOA

Increase myocardial O2 supply by blocking beta receptors

Lengthen the amount of time blood takes to enter the coronary arteries

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Atenolol SE /labs
Severe SE

Pt precaution

Decreased HR/RR/BP: stand slowly
Pulmonary edema: no asthma
Impotence
Severe: AV block, HF

Labs: Creatinine/BUN

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Botulism antitoxin MOA

Slows progression of neuro symptoms

DOES NOT REVERSE

attaches to toxin in blood and keep it from harming other nerves

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Allopurinol indication

Tumor lysis syndrome

Chemo

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Allopurinol Classification

Anti-gout

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Botulism labs

Horse serum

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Botulism side effect/Lab

Don’t give with

Allergic reaction

NO honey for babies

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Captopril Indication

HTN
PAD
Acute MI

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Captopril MOA

Decreases BP
Increases peripheral blood flow and walking distance
Decreases workload of the heart, preventing remodeling (hypertrophy and cardiomyopathy)

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Captopril SE / lab

Angioedema
Hypotension
Cough
Bradycardia
Hyperkalemia

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Cilostazol (Pletal) indication and action

DONT give with

PAD: 1st IC
Inhibit platelet, cause vasodilation, increase walking

CONTRADICTED with HF

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Tegretol indication

Neuralgia
Neuropathic pain
Seizures / Bipolar

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Tegretol MOA

Surpassed high neuronal discharge and

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Don’t give tegretol with

Careful give with

Birth control
Warfarin
Grapefruit juice (^levels)

Asian or suppressed bone marrow

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Tegretol SE

Neuro effects, birth defects, skin defects

Bone marrow suppression
- Anemia, thrombocytopenia, leukopenia

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Dustasteride (Avodart) classification

Androgen (Reductase) inhibitor

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Dustasteride (Avodart) Indication

BPH

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Dustasteride (Avodart) MOA

Reduce prostate size
Decrease PSA
93% reduction of DHT

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Dustasteride (Avodart) SE/labs

Decreased ejaculatory volume
Decreased libido

Monitor PSA
5 week half life

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Erythropoietin (Epogen) classification

Growth Stimulator

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Erythropoietin (Epogen) Indication

Anemia

CKD

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Erythropoietin (Epogen) MOA

Stimulates RBC growth in bone marrow

Erythropoietin (Epogen) SE/lab

HTN, CV events Monitor CBC, H&H BUN, Creatinine Uric acid

Filgrastim (Neupogen) Classification

Colony stimulating factor

Filgrastim (Neupogen) Indication Main and what causes this

NEUTROPENIA Infection Cancer May be used prophylactically when highly myelosuppressvie drugs are being used

Filgrastim (Neupogen) MOA

Increase production of neutrophils

Filgrastim (Neupogen) SE/ labs

Bone pain Leukocytosis Monitor neutrophils

Finasteride (Proscar) classification

Androgen (reductase) inhibitor

Finasteride (Proscar) Indication

BPH Overflow incontinence

Finasteride (Proscar) MOA

Reduce prostate size Decrease PSA Decrease outlet resistance

Finasteride (Proscar) SE/labs

Decreased libido and ejaculatory volume Monitor PSA

Doxazosin (cardura)

Relax sm muscle in bladder neck to facilitate urine flow

Pyridium

UTI discomfort

Heparin indication

Prevent clotting, MI, stroke

Heparin MOA

Decrease clotting factors and activation of vit K

Heparin labs

aPTT

Lactulose Classification

Osmotic Laxative

Lactulose Indication

Constipation High ammonia in cirrhosis Encephalopathy

Lactulose SE / labs

Diarrhea | Ammonia

Lactulose MOA

Increases mental status in encephalopathy by draining ammonia out and excrete it through diarrhea

Omeprazole PPI (Prilosec) Indication

PUD Gerd Prevention of stress ulcers

Omeprazole (Prilosec) MOA

Decrease HCl secretion | Decrease irritation of esophageal and gastric mucosa

Omeprazole (Prilosec) SE

Dizziness, Diarrhea, Bloating

Simvastatin MOA

Lower LDL Slow atherosclerosis Prevent MI, Stroke

Kayexalate Indication

Hyperkalemia

Kayexalate MOA

Resin on bowel exchanges sodium for K and evacuating it in bowel movement

Kayexalate SE Don't give with

Diarrhea DO NOT GIVE with paralytic ileus

Protamine Sulfate SE

HTN Severe bradycardia Pulmonary edema

Reserpine (Serpasil) Classification

Alpha adrenergic blocker

Reserpine (Serpasil) Indication

Raynaud's | HTN

Reserpine (Serpasil) MOA

Increased blood flow to the fingers Depression of NE from SNS nerves Cause vasodilation

Reserpine (Serpasil) SE

Depression d/t decreased dopamine Bradycardia, hypotension

Vitamin K - indication/MOA/SE/labs

``` Antidote - Warfarin Promote clotting SE: Embolism PT- 2-3 INR- 11-16 ```

Warfarin labs

PT | INR

Zidovudine (AZT) Classification

NNRTI

Zidovudine (AZT) Indication

HIV and chronic Hepatits

Zidovudine (AZT) MOA

Inserted piece of DNA into developing strand, blocking further development and incomplete DNA strand

Zidovudine (AZT) SE/labs

Anemia, leukopenia Monitor CD4 and WBC

Cardiziem Indication

Raynauds - Decrease vasospasm A-fib with rapid ventricular response Tachycardia (Low Ca=low contractility)

Surgery & clotting

Want lower INR/PT,aPTT

Angina d/t ischemia and we want to increase blood flow

Give nitro FIRST and if that doesn't work q5 min for 3 times, give morphine

Allopurinol indication

Tumor lysis syndrome Chemo Renal failure