Meds Flashcards

1
Q

Allopurinol MOA

A

Decrease uric acid

Prevents renal damage r/t chemo bc cells die and the break down of DNA releases Uric acid

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2
Q

Allopurinol SE/labs

When to stop

A

Nephrotoxic
Monitor Uric acid
STOP: rash or fever

Se: metallic taste, cataracts

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3
Q

Atenolol indication

A

Raynauds
Dysrhythmias
HTN

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4
Q

Atenolol MOA

A

Increase myocardial O2 supply by blocking beta receptors

Lengthen the amount of time blood takes to enter the coronary arteries

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5
Q

Atenolol SE /labs
Severe SE

Pt precaution

A

Decreased HR/RR/BP: stand slowly
Pulmonary edema: no asthma
Impotence
Severe: AV block, HF

Labs: Creatinine/BUN

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6
Q

Botulism antitoxin MOA

A

Slows progression of neuro symptoms

DOES NOT REVERSE

attaches to toxin in blood and keep it from harming other nerves

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7
Q

Allopurinol indication

A

Tumor lysis syndrome

Chemo

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8
Q

Allopurinol Classification

A

Anti-gout

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9
Q

Botulism labs

A

Horse serum

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10
Q

Botulism side effect/Lab

Don’t give with

A

Allergic reaction

NO honey for babies

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11
Q

Captopril Indication

A

HTN
PAD
Acute MI

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12
Q

Captopril MOA

A
  • Decreases BP
  • Increases peripheral blood flow and walking distance
  • Decreases workload of the heart, preventing remodeling (hypertrophy and cardiomyopathy)
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13
Q

Captopril SE / lab

A
Angioedema
Hypotension
Cough
Bradycardia
Hyperkalemia
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14
Q

Cilostazol (Pletal) indication and action

DONT give with

A

PAD: 1st IC
Inhibit platelet, cause vasodilation, increase walking

CONTRADICTED with HF

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15
Q

Tegretol indication

A

Neuralgia
Neuropathic pain
Seizures / Bipolar

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16
Q

Tegretol MOA

A

Surpassed high neuronal discharge and

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17
Q

Don’t give tegretol with

Careful give with

A

Birth control
Warfarin
Grapefruit juice (^levels)

Asian or suppressed bone marrow

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18
Q

Tegretol SE

A

Neuro effects, birth defects, skin defects

Bone marrow suppression
- Anemia, thrombocytopenia, leukopenia

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19
Q

Dustasteride (Avodart) classification

A

Androgen (Reductase) inhibitor

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20
Q

Dustasteride (Avodart) Indication

A

BPH

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21
Q

Dustasteride (Avodart) MOA

A

Reduce prostate size
Decrease PSA
93% reduction of DHT

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22
Q

Dustasteride (Avodart) SE/labs

A

Decreased ejaculatory volume
Decreased libido

Monitor PSA
5 week half life

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23
Q

Erythropoietin (Epogen) classification

A

Growth Stimulator

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24
Q

Erythropoietin (Epogen) Indication

A

Anemia

CKD

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25
Q

Erythropoietin (Epogen) MOA

A

Stimulates RBC growth in bone marrow

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26
Q

Erythropoietin (Epogen) SE/lab

A

HTN, CV events

Monitor CBC, H&H
BUN, Creatinine
Uric acid

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27
Q

Filgrastim (Neupogen) Classification

A

Colony stimulating factor

28
Q

Filgrastim (Neupogen) Indication

Main and what causes this

A

NEUTROPENIA

Infection
Cancer

May be used prophylactically when highly myelosuppressvie drugs are being used

29
Q

Filgrastim (Neupogen) MOA

A

Increase production of neutrophils

30
Q

Filgrastim (Neupogen) SE/ labs

A

Bone pain
Leukocytosis

Monitor neutrophils

31
Q

Finasteride (Proscar) classification

A

Androgen (reductase) inhibitor

32
Q

Finasteride (Proscar) Indication

A

BPH

Overflow incontinence

33
Q

Finasteride (Proscar) MOA

A

Reduce prostate size
Decrease PSA
Decrease outlet resistance

34
Q

Finasteride (Proscar) SE/labs

A

Decreased libido and ejaculatory volume

Monitor PSA

35
Q

Doxazosin (cardura)

A

Relax sm muscle in bladder neck to facilitate urine flow

36
Q

Pyridium

A

UTI discomfort

37
Q

Heparin indication

A

Prevent clotting, MI, stroke

38
Q

Heparin MOA

A

Decrease clotting factors and activation of vit K

39
Q

Heparin labs

A

aPTT

40
Q

Lactulose Classification

A

Osmotic Laxative

41
Q

Lactulose Indication

A

Constipation
High ammonia in cirrhosis
Encephalopathy

42
Q

Lactulose SE / labs

A

Diarrhea

Ammonia

43
Q

Lactulose MOA

A

Increases mental status in encephalopathy by draining ammonia out and excrete it through diarrhea

44
Q

Omeprazole PPI (Prilosec) Indication

A

PUD
Gerd
Prevention of stress ulcers

45
Q

Omeprazole (Prilosec) MOA

A

Decrease HCl secretion

Decrease irritation of esophageal and gastric mucosa

46
Q

Omeprazole (Prilosec) SE

A

Dizziness, Diarrhea, Bloating

47
Q

Simvastatin MOA

A

Lower LDL
Slow atherosclerosis
Prevent MI, Stroke

48
Q

Kayexalate Indication

A

Hyperkalemia

49
Q

Kayexalate MOA

A

Resin on bowel exchanges sodium for K and evacuating it in bowel movement

50
Q

Kayexalate SE

Don’t give with

A

Diarrhea

DO NOT GIVE with paralytic ileus

51
Q

Protamine Sulfate SE

A

HTN
Severe bradycardia
Pulmonary edema

52
Q

Reserpine (Serpasil) Classification

A

Alpha adrenergic blocker

53
Q

Reserpine (Serpasil) Indication

A

Raynaud’s

HTN

54
Q

Reserpine (Serpasil) MOA

A

Increased blood flow to the fingers

Depression of NE from SNS nerves

Cause vasodilation

55
Q

Reserpine (Serpasil) SE

A

Depression d/t decreased dopamine

Bradycardia, hypotension

56
Q

Vitamin K - indication/MOA/SE/labs

A
Antidote - Warfarin
Promote clotting
SE: Embolism
PT- 2-3
INR- 11-16
57
Q

Warfarin labs

A

PT

INR

58
Q

Zidovudine (AZT) Classification

A

NNRTI

59
Q

Zidovudine (AZT) Indication

A

HIV and chronic Hepatits

60
Q

Zidovudine (AZT) MOA

A

Inserted piece of DNA into developing strand, blocking further development and incomplete DNA strand

61
Q

Zidovudine (AZT) SE/labs

A

Anemia, leukopenia

Monitor CD4 and WBC

62
Q

Cardiziem Indication

A

Raynauds - Decrease vasospasm
A-fib with rapid ventricular response
Tachycardia

(Low Ca=low contractility)

63
Q

Surgery & clotting

A

Want lower INR/PT,aPTT

64
Q

Angina d/t ischemia and we want to increase blood flow

A

Give nitro FIRST and if that doesn’t work q5 min for 3 times, give morphine

65
Q

Allopurinol indication

A

Tumor lysis syndrome
Chemo
Renal failure