Meds Flashcards

0
Q

CCB

A

Cause peripheral edema
Constipation
Headache

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1
Q

Risperidone

A

D2 antagonist - causes weight gain, hyperprolactinemia,

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2
Q

Steroids

A

Cause acne that is monomorphic pink papules with no comedones

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3
Q

Nitroglycerin effects

A

Dilates capacitance vessels - decreases preload

Dilates arterioles - decreases afterload –> decreases BP –> reflex tachycardia and increased contractility

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4
Q

Amiodarone

A

Don’t give to patients with pre-existing lung disease!!! can cause ARDS, interstitial pneumonitis, organizing pneumonia

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5
Q

Lidocaine

A

Increases the risk of asystole in patients with acute coronary syndromes

Decreases risk of V-fib

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6
Q

Which drugs are CI in heart block?

A

Bb
Digoxin
CCB

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7
Q

Which things increase warfarin effect?

A
Acetaminophen 
NSAIDs
Ginkgo biloba
Omeprazole
Cranberry juice
Vit E
Thyroid hormone 
SSRI
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8
Q

Which things decrease warfarin effect?

A
Green veggies
Carbamazepine 
Rifampin 
OCPs
Ginseng 
St. John's wort
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9
Q

Efavirenz

A

Causes vivid dreams, insomnia

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10
Q

Didanosine

A

Pancreatitis

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11
Q

Beta 2 agonists used for preterm labor tocolysis

A

May result in pulmonary edema due to tachy from beta 1 stimulation (decreased filling time and subsequent backup)

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12
Q

Risperidone

A

Most likely atypical antipsychotic to cause extrapyramidal sx and tardive dyskinesia

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13
Q

Clozapine

A

Most effective atypical antipsychotic in schizophrenia
Least likely to cause extrapyramidal sx
Causes agranulocytosis

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14
Q

Which medications cause crystal induced kidney injury?

A
Acyclovir
Sulfonamides
MTX 
Ethylene glycol
Protease inhibitors (-Navir)
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15
Q

What can primaquine cause?

A

Methemoglobinemia

Hemolytic anemia

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16
Q

What is a side effect of norepinephrine?

A

Vasospasm leading to ischemia and necrosis of the fingers and toes in hypotensive patients

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17
Q

What are the drugs that cause esophagitis?

A
Tetracyclines
NSAIDs
Bisphosphonates
KCl
Quinidine
Iron
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18
Q

What side effect can be seen after levo/carbidopa?

A

Hallucinations

19
Q

What drug causes livedo reticular is and ankle edema?

A

Amantadine

20
Q

Which drugs cause hyperkalemia?

A
Trimethoprim
Nonselective Bb
ACEi
Heparin 
Cyclosporine 
NSAIDs 
Succinylcholine
21
Q

What are the main side effects of sulfonylureas?

A

Weight gain

Hypoglycemia

22
Q

What are the side effects of pioglitazones?

A
Weight gain
Edema
CHF 
Bladder cancer 
Bone fx
23
Q

What are the side effects on insulin?

A

Weight gain

Hypoglycemia

24
Q

When is insulin added to Type II regimen?

A

When A1C is greater than 8.5% and metformin failed

25
Q

What is the best diabetic medication if weight loss is desired?

A

GLP-1 agonist

26
Q

What are GLP1 agonists associated with?

A

Acute pancreatitis

27
Q

What drugs cause hypothermia?

A

Typical antipsychotics : fluphenazine, haloperidol, chlorpromazine, trifluoperazine,

28
Q

What is the side effect of methimazole?

A

Agranulocytosis
Teratogen
Cholestatic jaundice

29
Q

What are the side effects of PTU?

A
Vasculitis
Rash
Arthralgia
Hepatotoxicity 
Agranulocytosis
30
Q

What are the side effects of radio iodine ablation?

A

Permanent hypothyroidism

Worsening of opthalmopathy

31
Q

What is the blackbox warning of PTU?

A

Severe liver injury

Acute liver failure

32
Q

Which drugs cause cholestasis?

A

Chlorpromazine
Anabolic steroids
Nitrofurantoin
Erythromycin

33
Q

Which meds cause fatty liver?

A

Tetracyclines
Valproate
Antiretrovirals

34
Q

Which meds cause hepatitis?

A

Halothane
Phenytoin
Isoniazid
Alpha-methyl dopa

35
Q

Which drugs granulomatous liver problems?

A

Allopurinol

Phenylbutazone

36
Q

What can primidone do?

A

Precipitate acute porphyria - abdominal pain, confusion, headache, hallucinations and dizziness

37
Q

Why should CCBs NOT be used in acute MI or CHF?

A

They cause reflex tachy and therefore increase demand on the heart
Also, cause edema

38
Q

Why are beta blockers contraindicated in pulmonary edema and CHF?

A

Because hey decrease contractility and can lead to worsening of the fluid overload
Should be started for long term management once the patient is euvolemic

39
Q

Which meds can cause NASH?

A
Amiodarone 
Steroids
Diltiazem 
Tamoxifen 
HAART
TPN
40
Q

What drugs can’t be used for PE in a patient with a GFR less than 30?

A

Enoxaparin
Fondaparinix
Rivaroxaban
Because decreased clearance increases the anti-Xa activi level and therefore the bleeding risk

41
Q

Which meds cause megaloblastic anemia due to impaired folic acid absorption?

A

Phenytoin
Primidone
Phenobarbital

42
Q

Erythropoietin causes what side effects?

A

HTN
Flushing
Headache
Red cell aplasia

43
Q

What are the side effects of cyclosporine?

A

Nephrotoxicity: most common and severe –> hyperuricemia with gout, hypophosphatemia, hyperkalemia, hypomagnesemia

HTN - tx with CCB

Neurotoxicity: headache, visual disturbances, seizures, tremors, akinestic mutism

Infection
Malignancy : SCC of the skin and lymphoproliferative disorders
Gingival hypertrophy and hirsutism
GI

44
Q

What does verapamil do to the digoxin concentration?

A

Increases it by decreasing its renal excretion

45
Q

What does digoxin toxicity cause?

A
Anorexia
Nausea
 Vomiting
Visual changes
Bi ventricular tachy and accelerated junctional rhythms