Medicines and Therapeutics in OM Flashcards
How to identify correct tx regime in primary care?
- SDCEP guidance
- BNF
Medicines in Oral Medicine
- anti-microbial
- topical steroids
- dry mouth medication
- Benzdamine MW
- Carbamazepine
Types of antimicrobials
- anti-viral
- anti-fungal
- antibiotics
Types of topical steroids
- inhaled steroids
- steroid MW
Classification of medicines
- general sales
- pharmacy medicines
- prescription only medicines
- controlled drugs
- medical devices
Licensed Medicines
- a medicine that has been proven in evidence to the MHRA to have efficacy and safety at defined doses in a child and/ or adult population when treating specified medical conditions
- usually clinical trial data provided by manufacturer
- post license surveillance via MHRA
MHRA stands for?
Medicines and Healthcare Products Regulatory Agency
Unlicensed medicines
- medicines that have not had evidence of efficacy submitted for the condition under tx
- might be licensed medicines for other tx
- off- license/ off-label will be at the discretion of treating physician
- pt must be informed that it is used off-license
- pt must be given PIL specific to condition under tx
- drug manufacturer supplied PIL will be for the licensed condition
What medicines are used licensed for use in OM?
Antivirals
- Aciclovir
- used to treat primary herpetic gingivostomatitis
- treat recurrent herpetic lesions
- treat shingles (recurrent herpes zoster)
Antifungal
- Miconazole, Fluconazole, Nystatin
- treat acute pseudomembranous candidiasis
- treat acute erythematous candidiasis
Topical steroids - unlicensed
- Betamethasone MW
- Beclomethasone Metered dose inhaler
- both used to treat aphthous ulcers and lichen planus
What are medical devices?
- any instrument, apparatus, implement, machine, appliance, implant, reagent for in vitro use, software, material or other similar/ related article, intended by the manufacturer to be used, alone or in combination for human beings, for one/ more specific medical purposes of :-
Dry Mouth tx
- Salivix pastilles
- Saliva orthana
- Biotene Oral Balance
- Artificial Saliva DPF
- Glandosane
Other medicines used in OM Specialist Practice
- Tricyclic antidepressants
- Gabapentin/ Pregabalin
- Azathioprine
- Mycophenolate
- Hydroxychloroquine
- Colchicine
Anti- viral
Aciclovir
Anti- fungal
- Miconazole
- Fluconazole
- Nystatin