Medicine Management Flashcards
Q: What are the two main categories of drug administration routes?
A:
Enteral: Involves the gastrointestinal tract (e.g., oral, gastric, rectal).
Parenteral: Bypasses the gastrointestinal tract (e.g., injections, inhalation, transdermal).
Q: What is the purpose of selecting different routes of drug administration?
A:
Ensures effective therapeutic response.
Depends on the drug’s required effect, target site, and patient factors.
Influences drug absorption, distribution, metabolism, and excretion (ADME).
Q: What are examples of enteral routes of administration?
A:
Oral (PO): Tablets, capsules, liquids.
Sublingual (SL): Under the tongue (e.g., Glyceryl Trinitrate).
Buccal: Between gum and cheek (e.g., Prochlorperazine).
Rectal: Suppositories and enemas.
Q: What are examples of parenteral routes of administration?
A:
Intravenous (IV): Direct into the bloodstream.
Intramuscular (IM): Injection into muscle tissue.
Subcutaneous (SC): Injection under the skin.
Inhalation: Inhalers and nebulizers (e.g., Salbutamol).
Transdermal: Absorption through the skin (e.g., fentanyl patches).
Q: What is important when administering oral medications?
A:
Swallow tablets whole unless scored.
Do not crush coated or slow-release tablets without pharmacist approval.
Provide with at least 50 mL of water to prevent tablets from sticking in the esophagus.
Q: What are the benefits of sublingual and buccal administration?
A:
Rapid absorption into the bloodstream via oral mucosa.
Bypasses the gastrointestinal tract and first-pass metabolism.
Q: How are medicines administered via feeding tubes?
A:
Use liquid preparations where possible.
Flush the tube with water between medications.
Confirm correct tube positioning before administration.
Q: When is the rectal route appropriate?
A:
For patients who are vomiting or unable to take oral medications.
Used for both local effects (e.g., hemorrhoids) and systemic effects (e.g., antiemetics).
Q: How is the inhalation route used for medication delivery?
A:
Delivers drugs directly into the lungs for rapid absorption.
Includes inhalers (e.g., Salbutamol) and nebulizers.
Q: What precautions should be taken with transdermal patches?
A:
Apply to clean, dry, and hairless skin.
Rotate application sites to avoid skin irritation.
Do not cut patches or expose them to heat.
Q: What is the correct method for aural (ear) medication administration?
A:
Adults: Pull the ear up and back.
Children: Pull the ear down and back.
Administer the correct number of drops as prescribed.
Q: What is the intranasal route and when is it used?
A:
Delivers medications via the nasal mucosa (e.g., Fluticasone for rhinitis).
Provides local or systemic effects.
Q: What are the types of injectable routes and their uses?
A:
Intravenous (IV): Immediate systemic effect.
Intramuscular (IM): Moderate absorption (e.g., vaccines).
Subcutaneous (SC): Slow absorption (e.g., insulin).
Intradermal (ID): Skin testing (e.g., tuberculosis test).
Q: What considerations should be made for topical medications?
A:
Apply only the prescribed amount.
Use gloves to avoid absorbing the medication.
Example: Steroid creams for eczema.
Q: How are vaginal medications administered?
A:
Using an applicator to insert creams or pessaries.
Example: Clotrimazole for fungal infections.
Q: What factors affect the choice of a drug’s route of administration?
A:
Speed of action required.
Target site accessibility.
Patient’s condition and preferences.
Drug formulation and stability.
Q: What is the difference between systemic and local drug effects?
A:
Systemic: Drug is absorbed into the bloodstream and affects the entire body.
Local: Drug acts only at the site of application (e.g., topical creams).
Q: Why must the route of administration be specified on prescriptions?
A:
Prevents confusion when a drug has multiple routes.
Ensures safe and effective drug delivery.
Q: What are risks of improper medication administration?
A:
Reduced drug effectiveness.
Increased risk of adverse effects or toxicity.
Blockage of feeding tubes if medications are crushed improperly.
Q: How does pharmacokinetics (ADME) relate to routes of administration?
A:
Determines how the body absorbs, distributes, metabolizes, and excretes drugs.
Affects the speed and efficacy of medication action.
Q: What are the advantages and disadvantages of the oral route?
A:
Advantages:
Convenient and non-invasive.
Cost-effective.
Suitable for self-administration.
Disadvantages:
Slower absorption.
Affected by food, digestive enzymes, and first-pass metabolism.
Not suitable for patients who are vomiting or unconscious.
Q: What are the advantages and disadvantages of the intravenous (IV) route?
A:
Advantages:
Immediate drug action.
100% bioavailability.
Precise dose control.
Disadvantages:
Invasive and requires trained personnel.
Risk of infection, phlebitis, or air embolism.
Q: What is the Z-Track technique in intramuscular (IM) injections?
A:
Used to prevent medication from leaking into subcutaneous tissue.
Pull the skin laterally before injection and release after withdrawing the needle.
Commonly used for irritating or staining medications (e.g., iron supplements).
Q: How does the speed of absorption vary between different routes of administration?
A:
Intravenous (IV): Immediate effect.
Inhalation: Very rapid (seconds to minutes).
Intramuscular (IM): Moderate (10–20 minutes).
Subcutaneous (SC): Slower than IM.
Oral: Slowest due to digestive processing.