Medicine (including all year 4 specialities) Flashcards
What is the gold standard investigation for bladder cancer diagnosis?
Cystoscopy
Sexual intercourse is a cause of transient visible haematuria, name 3 more.
Vigorous exercise
Urinary tract infection
Menstruation
Cancer and renal stones are two causes of persistent visible haematuria, name 4 more.
benign prostatic hyperplasia
prostatitis
urethritis e.g. Chlamydia
renal causes: IgA nephropathy, thin basement membrane disease
Which malignancy does a H.pylori infection predispose to?
Gastric lymphoma (MALT)
What is the firstline investigation for suspected leptospirosis?
Serology
The patient who has a job as a sewage worker presents with fevers, myalgia, headache, conjunctival redness, jaundice and dark urine. What is the most likely diagnosis?
Leptospirosis
Following an ACS what medications should all patients be offered?
Dual antiplatelet therapy (aspirin plus a second antiplatelet agent)
ACE inhibitor
Beta-blocker
Statin
What is the most common cause of viral meningitis in adults?
Enteroviruses (Coxsackievirus B)
What nerve conduction study result would support a diagnosis of MND?
Normal results.
How long must voice hoarseness be present for, for it to be considered persistent?
> 3 weeks
Fatigue is an early sign of haemochromatosis, name two more.
Erectile dysfunction
Arthralgia
What is the most common cause of death for patients with CKD on haemodialysis? Why?
Ischaemic heart disease
This is due to several factors including hypertension, dyslipidaemia, anaemia and systemic inflammation that are common in CKD patients.
What is the most suitable option for renal replacement therapy for a patient with Crohn’s disease? Why?
Haemodialysis
Insertion of the peritoneal dialysis would be complicated by the Crohn’s disease.
Define Rapidly Progressive Glomerulonephritis.
Rapid loss of renal function associated with the formation of epithelial crescents in the majority of glomeruli.
Goodpastures syndrome is a cause of Rapidly Progressive Glomerulonephritis, name 3 more.
Wegener’s granulomatosis
SLE
Microscopic polyarteritis
What is the gold standard investigation for suspected optic neuritis?
MRI contrast of the orbits and brain (gadolinium).
What are the features of Brocas aphasia?
Non-fluent
Comprehension normal
Repetition impaired
Management of tricyclic antidepressant overdose:
- …
- Give 50 grams of charcoal if within one hour of ingestion.
- Give sodium bicarbonate (50 ml of 8.4%) if:
pH <7.1
QRS >160 ms
Arrhythmias
Hypotension
Consider gastric lavage only if within one hour of a potentially fatal overdose.
Management of tricyclic antidepressant overdose:
- Consider gastric lavage only if within one hour of a potentially fatal overdose.
- …
- Give sodium bicarbonate (50 ml of 8.4%) if:
pH <7.1
QRS >160 ms
Arrhythmias
Hypotension
Give 50 grams of charcoal if within one hour of ingestion.
Management of tricyclic antidepressant overdose:
- Consider gastric lavage only if within one hour of a potentially fatal overdose.
- Give 50 grams of charcoal if within one hour of ingestion.
- …
Give sodium bicarbonate (50 ml of 8.4%) if:
pH <7.1
QRS >160 ms
Arrhythmias
Hypotension
How are arrhythmias managed in a TCA overdose?
avoid antiarrhythmics, correct hypoxia, hypotension, acidosis, hypokalaemia.
Where is the most common location for a metatarsal stress fracture?
The most common site of metatarsal stress fractures is the 2nd metatarsal shaft
In pregnant woman who develop hyperthyroidism in the first trimester, …… is preferred over carbimazole due to lower risk of …..
propylthiouracil
foetal malformation
Polycythaemia rubra vera - around …… progress to myelofibrosis or AML
5-15%