Medicine general Flashcards
Asthma
Chronic obstructive lung disease with bronchiolar inflammation, and hyper-responsiveness.
Cystic Fibrosis
Autosomal Recessive disease that results in altered chloride and water transport across epithelial cells
COPD
Chronic obstructive lung disease, irreversible. Includes both emphysema and chronic bronchitis
Pulmonary Embolism
acute obstruction in the pulmonary arterial vasculature leading to V/F mismatch
COVID
Viral disease causing by SARV-CoV2 with major systemic implications including lung disease
Allergic Rhinitis
IgE mediated inflammatory process of the nasopharynx, oropharynx with allergen exposure
Acute Kidney Injury (AKI)
Loss of renal fx over hours / days due to disturbances in fluid, electrolyte, and acid-base homeostasis.
Chronic kidney disease
Permanent renal insufficiency that develops over months / years. Caused by structural intrinsic damage of the glomerulus or tubulo-interstitial system.
Anemia
Decreased in RBCs -> less oxygen carrying capacity and delivery in end organs
Leukemia
Disease of mesenchymal cells of the blood -> abnormal proliferation or increased lifespan of myeloid / lymphyoid cells.
Hemophilia
X-linked recessive bleeding disorder
Von WIllebrnad
Congential platelet bleeding disorder due to the dysfunction of von Willebrand Factor (vWF)
Anti-thrombin III Def
Inherited Def of antithrombin III leading to increase risk of recurrent thrombosis (DVP, PE)
Lymphoma
Malignancy of lymphocytes that usually arrises in the lymph nodes
Multiple Myeloma
Disease characterized by the neoplastic transformation of plasma cells producing a monoclonal immunoglobin
Systemic Lupus Erythematous
Multisystem chronic inflammatory disorder characterized by auto-antibody production causing immune-mediate tissue damage
Rheumatoid Arthritis
Chronic Systemic inflammatory Disease characterized by inflammatory poly-arthritis with progressive destruction of joint, bone, and aritcular cartilage
Osteoarthritis
Painful Degenerative process involving progressive deterioration of articular cartilage and remodeling of subcondral bone (NON INFLAMMATORY)
Obesity
Abnormally high amount of adipose tissue compared with lean muscle mass with excess body weight > 20% over the predicated ideal body weight
Muscular Dystrophy
Inheritable myopathies causing progressive death of muscle fibers
Myasthenia Gravis
Autoimmune disorder affecting post-synaptic Neuromuscular transmission of the nicotinic ACH receptor due to the production of autoantibodies.
Ehler-Danlos Syndrome
Inherited disease results from a defect in synthesis of fibrillar collagen lead to changes in skin, tendons, blood vessels and viscera
Marfan Syndrome
autosomal dominant CT disorder affecting cardiac, skeletal and ocular issues
Hyperthyroidism
A condition in which the thyroid gland is hyperactive. Manifistation including sweating, cardiac issues (tachycardia, contractility), increase BP, weight loss, diarrhea, restlessness, heat intolerance
Grave’s disease
Autoimmune condition resulting in hyperstimulation of TSH receptors from auto-antibodies
Thyroid storm
Acute exacerbation of hyperthyroidism that is life-threatening
Myxedema
=hypothyrodism: Condition where the thyroid gland has decreased production of the thyroid hormone resulting in low T3 and T4.
Hashimoto’s thyroditis
Autoimmune hypothyroidism caused of destruction of thyroid gland.
Type 1 DM
=insulin dependent diabetes. Autoimmune Metabolic disease: Loss of insulin producing beta cells of the islet of Langerhan in the pancreas
Type 2 DM
Metabolic disease of altered number and affinity of peripheral insulin receptions.