Medicine 8 Flashcards
List some causes of palmar erythema.
Cirrhosis Hyperthyroidism Rheumatoid arthritis Pregnancy Polycythaemia
List some causes of gynaecomastia.
Physiological (puberty) Drugs (spironolactone, digoxin, cimetidine, finasteride) Cirrhosis Testicular tumour/orchidectomy Kleinfelter's and Kallman syndrome
List some clinical features of haemochromatosis.
Testicular atrophy Diabetes mellitus (injection sites) Congestive cardiac failure Arthropathy Chronic liver disease
What are the main indications for splenectomy?
Rupture (trauma)
Haematological (ITP, hereditary spherocytosis, sickle cell disease)
How do patients with polycystic kidney disease tend to present?
Hypertension Recurrent UTI Abdominal pain (bleeding into cyst or cyst infection) Haematuria End-stage renal failure
NOTE: may present with extra-renal manifestations such as subarachnoid haemorrhage, mitral valve prolapse and hepatic cysts
List some signs of interstitial lung disease.
Clubbing Central cyanosis Fine end-inspiratory crackles Signs of autoimmune disease (e.g. rheumatoid arthritis, SLE, SS) Grey skin (amiodarone)
List some causes of apical fibrosis.
TB Radiation Ankylosing spondylitis ABPA Sarcoidosis Histoplasmosis EAA
List some clinical signs of COPD.
Central cyanosis Pursed lip breathing CO2 retention flap/bounding pulse Tar stained fingers Expiratory polyphonic wheeze Cor pulmonale (raised JVP, ankle oedema, RV heave, loud P2)
Outline the management of COPD.
Smoking cessation Beta-agonists (salbutamol) Tiotropium bromide Inhaled corticosteroids Vaccinations (influenza, pneumococcus) Pulmonary rehabilitation LTOT
List some surgical treatment options for COPD patients.
Bullectomy
Endobronchial valve placement
Lung reduction surgery (if heterogenous distribution of emphysema)
Single lung transplant
List some differentials for a wheezy chest.
COPD Asthma Bronchiectasis Granulomatosis with polyangiitis (obliterative bronchiolitis) Rheumatoid arthritis
List the criteria for starting long-term oxygne therapy.
Non-smoker
PaO2 < 7.3 kPa on air
PaO2 7.3-8 with secondary polycythaemia, peripheral oedema, or evidence of pulmonary hypertension
List some clinical signs of a pleural effusion.
Asymmetrically reduced expansion Trachea deviated away from effusion Stony dull percussion Absence tactile vocal fremitus Reduced breath sounds Bronchial breathing above fluid level
List some complications of lung cancer.
Superior vena cava obstruction Recurrent laryngeal nerve palsy Horner's syndrome Wasting of small muscles of hand Endocrine (gynaecomastia) Neurological (Lambert-Eaton) Dermatomyositis
List some differentials for systolic murmurs.
Aortic stenosis Aortic sclerosis Mitral regurgitation HOCM VSD Aortic flow murmur
List some clinical signs of aortic stenosis.
Slow rising pulse
Narrow pulse pressure
Ejection systolic murmur
Thrill over aortic area
What is the EuroSCORE?
A risk model that calculates the risk of death after a cardiac operation
List some clinical signs of tricuspid regurgitation.
Raised JVP (giant V waves)
Pansystolic murmur loudest in tricuspid area
Thrill at left sternal edge
Pulsatile liver, ascites and peripheral oedema
Endocarditis signs (IVDU)
Pulmonary hypertension (loud P2)
List some indications for having an ICD.
Familial conditions with high risk of sudden cardiac death (long QT, ARVD, brugada, HCM)
Cardiac arrest due to VT/VF
Haemodynamically compromising VT
VT with LVEF < 35%
List some clinical signs of constrictive pericarditis.
Raised JVP
Right heart failure
Kussmaul sign (paradoxical increase in JVP on inspiration)
Pulsus paradoxus (>10 mm Hg drop in SBP on inspiration)
Hepatomegaly, ascites and peripheral oedema