medicine Flashcards

1
Q

Use of ether

A
  • Robert Liston in 1846 used ether during an operation to amputate a leg.
  • People watching were astonished to see that he didn’t need to be held down, and he woke up not remembering the operation
  • There were problems. Caused vomiting and irritated the lungs, making patients cough, and it could leave the patients asleep for either hours or days
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

chloroform

A
  • James simpson 1847
  • wanted to find a better anaesthetic, and carried out experiments inhaling various gases
  • He discovered chloroform was an effective anaesthetic, and did not seem to have the same side effects as ether
  • Simpson used chloroform on women in 1847 in childbirth. He used it on Queen Victoria in Scotland in 1853, and due to the royal approval, patients started requesting for chloroform in their operations
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

CHLOROFORM PROBLEMS

A
  • The christian church was opposed to the use of it during childbirth
  • Many doctors were opposed to the use of it during childbirth because it was not known how it would affect the baby
  • It was difficult to get the dose right
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

EFFECTS OF CHLOROFORM

A
  • Gave surgeons more time to work, so they could carry out more complicated operations and go deeper into the body
  • Still did not understand hygiene and infection, so they would still do the same unhygienic practices, but now going deeper into the body causing horrible infections
  • The increased length of time for operations caused problems eg if the blood supply to a part of the body was cut off for too long, increased risk of gangrene
  • John snow made an inhaling device that would control the dose of chloroform
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

PROBLEMS IN BRITISH PUBLIC HEALTH

A
  • A family would often live in a single room and 50 or more might live in one house
  • Houses were damp, with little ventilation
    In bad weather, tye ground floor could become flooded
  • A single privy might be used by 100 people
    Water was collected from a local pump sharing 20-30 families
  • The water was often taken from polluted rivers
    Disease spread rapidly
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

THE CHOLERA THREAT

A
  • Killed quickly - sometimes within a day
  • Symptoms involved general pain, muscle spasms, extreme vomiting and diarrhoea
  • Approximately 20,000 people had died in the epidemic of 1831-32
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

EDWIN CHADWICK AND THE 1848 PUBLIC HEALTH ACT

A
  • Set up a general board of health
  • Allowed towns to set up their own local board of health, employ a medical officer, organise the removal of rubbish and build a sewer system
  • Appointed three commissioners for the board of health; Chadwick was one of the three
  • Commissioner for london’s metropolitan commission of sewers from 1848-49
  • The impact was really limited
  • The terms were temporary - the board of health only was set up for 5 years
  • Allowed, but didn’t force so most did not take action
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

JOHN SNOW AND THE BROAD STREET PUMP

A
  • He investigated an outbreak of cholera in london using scientific methods to observe
  • He came to the conclusion that cholera was caused by dirty sewage/drinking water
  • Snow’s work had demonstrated the link between cholera and infected water and this put pressure on the water companies, local authorities, and parliament to improve water supplies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

PASTEUR’S EXPERIMENTS

A
  • He carried out experiments on milk, wine and vinegar
  • He became convinced that liquids were being contaminated with microorganisms that floated in the air
  • He proved that the idea of spontaneous generation was wrong by leaving a mixture in a container that was open, the mixture would go bad and microorganisms would be seen in it - however, if he heated the mixture and prevented air from reaching it, the mixture did not go bad
  • General date given for pasteur’s germ theory is 1861 because this is when he published his experiments
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

IMPACT OF GERM THEORY ON SURGERY

A

It led to an understanding of why infection often developed after an operation and to Lister’s development of antiseptic techniques.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Improvements in surgery: Lister and the impact of antiseptics

A
  • In one case, an 11-year-old boy was brought into the hospital with a broken leg. Usual treatment would be amputation as the bone was sticking out the skin, but lister set the broken bone and covered the wound in carbolic acid-soaked bandages. The wound healed without infection.
  • He began to use carbolic acid to clean wounds, equipment and bandages in all his operations
  • The death rate from infection dropped dramatically
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

OPPOSITION TO LISTER’S METHODS

A
  • The spray made instruments slippery, and difficult to grip which slowed the operation
  • Spray made doctor’s hands cracked and sore
  • Some doctors didn’t use it properly and didn’t find them effective
  • Extra time in dressing wounds
  • He kept adjusting techniques - people were worried that he wasn’t confident
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

The significance of Public Health Act (1875)

A

There was pressure on the parliament to get involved
The public health act 1875 made local authorities responsible for:
- the supply of clean water
- dealing with sewage in a way that would prevent it polluting the water used for drinking and washing
- building public toilets
- ensuring that new housing was built to good standards
- inspecting conditions in lodging houses
- employing health inspectors to make sure regulations were obeyed
- creating street lighting to avoid accidents
- checking the quality of food on sale
This act was hugely significant as it reflects the way that the attitude was changing and parliament was now passing laws to enforce a national standard of public health

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Nightingale and continuing improvements in hospitals and nursing

A
  • Newspaper reports of her work in the Crimea had made Nightingale famous
  • When she returned to britain in 1856, she was seen as an expert in working on nursing
  • She did very little nursing personally but she was an excellent organiser and manager
  • For this reason, she had a major impact on hospitals
  • She wrote multiple books such as notes on nursing in 1859 which gave advice on the importance of ventilation, bedding, cleanliness and food for patients
  • The books had a great influence even outside britain, and was translated into 11 different languages
  • In 1860, the nightingale school for the training of nurses was established at st thomas’s hospital in london
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Elizabeth Garrett and the progress of women in medicine

A
  • Elizabeth blackwell was an english woman whose family had moved to the USA, where she became the first woman to qualify as a doctor
  • She met garrett in one of her lectures
  • Garrett’s family was shocked at her dream of wanting to become a doctor
  • She became a nurse at middlesex hospital and attended lectures that were provided for the male doctors - until they complained
  • Garrett applied to study medicine at several medical schools but they all refused to accept a woman student
  • She completed her course of medical training but she could not be licensed
  • Garrett’s father - now supported her and threatened to sue the society of apothecaries if it did not accept her
  • She opened st mary’s dispensary in london to provide medical treatment for women
  • She went to paris for a medical degree
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what did he want to do, how did he do it?

Koch.

A
  • Koch wanted to prove that it was the anthrax microorganism which caused the disease
  • After he was gifted a microscope, he set up a small lab in his home in 1872 and published his work in 76
  • He developed methods of staining and photographing microorganisms
  • He published his works of bacterial infections in wounds in 1878
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

WHY KOCH’S WORK WAS IMPORTANT

A

He showed that these techniques could be used to investigate a number of diseases and could lead to new ways of preventing diseases

18
Q

PASTEUR AND CHICKEN CHOLERA

A
  • In 1878, pasteur published his germ theory of infection, in which he linked disease to microorganisms
  • His team were studying chicken cholera by injecting chickens with a culture of bacteria
  • When Pasteur’s assistant went on holiday, a culture of the bacteria was left on one side and not used until a couple weeks later - chickens injected with this culture did not develop chicken cholera, so they were injected with a fresh culture - they still did not develop chicken cholera
  • Pasteur and his team realised that the first batch had been weakened by the delay in using it.
  • Injecting this weakened version had stimulated the chicken’s natural defences, so it was able to fight against the fresh culture
  • This paved the way for further research to develop vaccination against other diseases
19
Q

VACCINATING PEOPLE

A
  • Pasteur wanted to investigate vaccines for human diseases but he could not test on people
  • He worked on a vaccine against rabies, and when it was still in the experimental stage, a 9 year old boy names joseph meister was brought to him after being bitten by a rabid dog
  • He gave him the injection, and the boy’s life was saved
20
Q

KOCH AND BACTERIOLOGY

A
  • Koch and his team identified the microorganisms for tuberculosis in 1882 and cholera in 1883
  • He developed the use of agar jelly for growing cultures in a petri dish
  • Koch had been called the ‘father of bacteriology’ because his methods and discoveries were the starting point for so many more discoveries
  • For example the microorganisms responsible for deadly diseases such as tetanus, pneumonia, meningitis, and dysentery were all identified in the 1880-90s
21
Q

HOW DID SURGERY IMPROVE (KOCH)

A

Koch developed a steam steriliser in 1878 and that caused a huge improvement in surgery - pasteur had shown that microorganisms could be killed by heat so koch developed the idea to use heat to sterilise equipment

22
Q

the impact of the Public Health Act (1875) for improving public health

A
  • The government had a major impact in public health in the years 1875-1905 because it passed a number of laws which made changes in hygiene and living standards
  • This reflects the changing attitudes towards the role of the government
  • Government started doing more support of ordinary people
  • New technologies made piped water and sewer systems possible
  • New understanding of disease also made it necessary to isolate patients with infectious diseases and highlighted the importance of the authorities to coordinate action
23
Q

BLOOD TRANSFUSIONS

A
  • Attempts to carry out blood transfusions had often caused the death of the patient and no one understood why
  • In 1901 karl landsteiner discovered that there were different blood types
  • Doctors realised that patients could die if they were given blood of a different type
  • Transfusions could now be carried out successfully
  • This would have a huge impact on surgery and would also help people who just had blood disorders such as leukaemia
  • The main problem now was that the donor had to be present in order for the transfusion to be carried out
  • Blood started to clot as soon as it leaves the body so the tubes used in transfusion could also become blocked
24
Q

PAUL EHRLICH AND THE FIRST MAGIC BULLET

A
  • Ehrlich wondered if he could create a chemical that would kill the microorganism causing a specific disease
  • If this worked, the microorganism would be killed without harming any others
  • Syphilis was largely feared, but the remedy was equally as dangerous because it involved mercury which caused kidney failure
  • In 1905 he tried to find a magic bullet for syphilis
  • In 1909, 606 different compounds were tried, and the first magic bullet was found
25
Q

MARIE CURIE

A

During the first world war, marie curie used her own money to help to equip ambulances with x-ray equipment - and even drove the ambulances to the front lines herself

26
Q

IMPROVING THE HEALTH OF CHILDREN (1906-1911)

A
  • There was a particular focus on helping children to grow up healthy
  • Local authorities received a grant from the government to cover half the cost of free school meals.
  • The number of meals provided increased from 3 million in 1906 to 14 million by 1914
  • This was a significant move: having at least one proper meal each school day would provide children with the food they needed to support their bodies’ growth and to improve their general health
  • The board of education also produced a booklet which was sent out to schools in 1906. The booklets said children should be taught about hygiene
27
Q

SCHOOL MEDICAL SERVICES

A
  • In 1907, the school medical service was set up
  • It checked on schoolchildren for illness and conditions such as ringworm or lice
  • Unfortunately if illness was found, many families couldn’t afford to even do anything about it
  • The children and young persons act, 1908, protected children by making it illegal to sell them tobacco or alcohol
28
Q

THE NATIONAL INSURANCE ACT 1911

A
  • Under the terms of this act, money was paid to the national insurance scheme by workers and their employers
  • Any worker who became ill could receive free medical care from a doctor linked to the scheme
  • They could also claim sickness benefit
  • A maternity grant was given to help to pay for baby essentials
  • The act was important because this was the first time that some groups in society had access to a trained doctor and treatment
  • Still not possible to treat many diseases such as tuberculosis, but treatment could help with symptoms
29
Q

Downside to national insurance act 1911

A
  • UNFORTUNATELY the act only applied to workers; if the family members became ill, they could not receive treatment
  • People who were self-employed were not covered
30
Q

The importance of the First World War for:
the role of women in medicine

A
  • The high number of casualties meant that they needed additional help
  • Marie curie was already driving an ambulance with x-rays for the french army
  • Many british women also volunteered to help
  • Many women joined the women’s army auxiliary corps which was set up in 1917
  • They would act as ambulance drivers and nurses, etc
  • Female doctors who wanted to volunteer upfront, were still being denied
  • The shortage of doctors during the war meant that attitudes changed towards women doctors but this change was only temporary
  • 12 london hospital schools began to accept women students during the war and the london school of medicine for women became the largest medical school in the country
  • Government encouraged women to volunteer
  • Thousands of untrained women worked as midwives or nurses
31
Q

The importance of the First World War for:
X-rays

A
  • By taking to x-rays from different angles, the surgeon was able to locate any metal in a wound very precisely
  • PROBLEMS WITH X-RAYS THAT PREVENTED THEM BEING USED TO FULL POTENTIAL:
  • X-rays could not be used to identify fragments of clothing within a wound
  • The wounded person had to remain still for some time which was a problem as they were in pain
  • The glass tubes used in x-ray machines often overheated after an hour, so they could not be in continuous use
  • The high dose of radiation in an x-ray was harmful and could cause burns (although the danger was not fully understood at this time)
32
Q

The importance of the First World War for:
blood transfusion and fighting infection.

A
  • Blood loss was a major problem during the war; many soldiers died from it even though their injuries would not have been fatal otherwise
  • The huge number of increased casualties in the war increased the need for blood transfusions
  • Scientists experimented with ways to prevent blood clotting and increase the time it could be stored
33
Q

The importance of the First World War for:
The thomas splint

A
  • Broken bones could break through the skin and create an open wound
  • Injured men had to be carried back from the front line to a casualty clearing station and injuries were often made worse as the patient was moved
  • It was a device that uses straps attaching over the pelvis or hip as an anchor, a metal rod to mimic normal bone stability and limb length, and a mechanical device to apply traction to the limb.
34
Q

The development of penicillin and the roles of Fleming, Florey and Chain.

A
  • In the first world war, alexander fleming had seen problems caused by infections in deep wounds
  • He also knew ordinary antiseptics were ineffective against these infections (septicaemia, gangrene)
  • He realised there was a need for a new treatment - like the magic bullet but to fight microorganisms causing infections
  • In 1922 he discovered an enzyme lysozyme, which can be found in tears and other body fluids, kills many microorganisms
  • He discovered mould that grew out of a petri dish with staphylococcus cultures and named in penicillin
  • This was different from magic bullet as it was an antibiotic
  • In 1929 fleming published his research, however few people realised the importance of this discovery
  • No progress had been made due to no funding, however in 1939 a team at oxford hospital led by florey and chain began to follow up on fleming’s research
  • In 1940 the team was able to purify enough penicillin to test on mice
  • By 1941, the team had purified enough to test it on a human
  • When they did, they discovered it worked tremendously and had the potential to save lives and they wanted to mass-produce it
35
Q

The importance of the Second World War for:
developments in surgery, including skin grafts and blood transfusion

A
  • When war broke out in 1939, britain had to deal with huge numbers of injuries
  • Emergency medical service was created in 1939
  • Penicillin was particularly effective in preventing gangrene, so its mass production later in the war was a major factor in increasing survival rates
  • In cases of severe damage, new skin may not be able to grow
  • Skin graft is a technique used where a layer of skin is taken from an undamaged area, and then transplanted to the damaged area
  • The transplanted tissue needs a good blood supply otherwise the graft will not grow
  • During the war the blood transfusion service was developed into an efficient organisation, storing and delivering blood wherever it was needed
36
Q

The importance of the Second World War for:
the role of women in medicine

A
  • Opened up opportunities and responsibilities for women to take on new roles
  • Number of female medical students increased from 2,000 to 2,900 from 1938-1946
  • Impact of WW2 was less than WW1 because fewer male doctors were called up to serve in the armed forces
  • Women took on various roles, including ambulance drivers, stretcher-bearers, and rescue service workers during air raids
  • The war accelerated the acceptance of women in medicine and paved the way for further advancements in gender equality within the profession.
37
Q

The importance of the Second World War for Beveridge, the development of the NHS and its importance for public health in Britain.

A
  • Sir William Beveridge published the “Social Insurance and Allied Services” report in 1942, which outlined a comprehensive social insurance and allied services system for Britain.
  • The report identified the “Five Giants” that needed to be addressed: Want, Disease, Ignorance, Squalor, and Idleness.
  • The report recommended the establishment of a - - - - National Health Service (NHS), which would provide universal healthcare for all citizens, free at the point of use.
  • The wartime experience and the need to maintain the health of the civilian population and returning soldiers highlighted the importance of accessible healthcare.
  • The Beveridge Report’s proposals gained widespread support, and the NHS was established in 1948 as a key component of the post-war welfare state.
  • The NHS has since become a cornerstone of British society, providing healthcare services to millions of people and significantly improving public health outcomes.
  • The Beveridge Report and the development of the NHS were critical turning points in the history of public health in Britain, with the Second World War serving as a catalyst for these reforms.
38
Q

Florence Nightingale background info

A
  • Came from a wealthy middle-class background
  • Family was shocked she wanted to train as a nurse - this was a very low paid job at the time
  • No formal hospital training for nurses in Britain, so spent 3 months in 1851 in Germany where training nurses had begun 20 years before
  • In 1853 she became superintendent of a small nursing home in london called ‘Institution for Sick Gentlewomen in Distressed Circumstances’
39
Q

Florence Nightingale SCUTARI

A
  • She was asked to take a team of 38 nurses to work in the military hospitals in scutari (Britain was fighting Russia in the Crimean Peninsula and a large number of deaths were caused by infection)
  • When she arrived the hospital was crowded and in appalling conditions
  • many men were sharing beds or lying on the floor
  • infested with lice and fleas
  • cholera was common
  • not enough medical supplies
  • poor quality food
40
Q

NIGHTINGALE’S ACTIONS SCUTARI

A
  • Cleaned the surfaces and washes all the sheets, towels and equipment
  • Opened windows to improve flow of air (miasma)
  • Improved food quality
  • A fund of money meant she could buy new supplies including towels, clean shirts, soap, plates, cutlery
41
Q
A