Medicine Flashcards

1
Q

How did the church control ideas in the Middle Ages?

A
  • It ran universities where physicians were trained
  • Priests could read and write unlike most people, this meant monasteries had lots of influence so what was written and read
  • Proved traditional, rational explanations for disease, they particularly liked Galen as his ideas fitted Christian beliefs
  • They taught that people should follow Jesus example and care for the sick, hospitals were often in monasteries
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2
Q

Who was Galen?

A
  • Roman doctor
  • Created the theory of opposites
  • Drew detailed diagrams of human anatomy after operating on wounded gladiators
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3
Q

Who was Hippocrates?

A
  • Ancient Greek doctor
  • Most treatments were based on diet, exercise, rest and for humours
  • Wrote the Hippocratic oath - doctors would respect life and prevent harm
  • Wrote the hippocratic collection, included symptoms and treatments
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4
Q

What was the theory of Miasma?

A
  • ‘Bad air’
  • It related to God because bad smells indicated sin
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5
Q

What were the religious and supernatural methods to prevent illness in the Middle Ages?

A
  • Living a Christian life
  • Carrying lucky charms or amulets
  • Chanting incantations
  • Self punishment, flagellation
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6
Q

What were the rational methods to prevent illness in the Middle Ages?

A
  • Trying to keep streets clean
  • Bathing and washing
  • Exercising
  • Not over eating
  • Bleeding and purging
  • Purifying the air
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7
Q

What were barber surgeons?

A
  • No medical training
  • Carried out bloodletting, pulling teeth and lancing boils
  • Did basic surgery such as amputating limbs, very low success rate
  • Cost less than a physician 
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8
Q

What were apothecaries?

A
  • Received training but no medical qualifications
  • Mixed medicines and ointments based on their own knowledge or directions of a physician
  • Cost money, but less than a physician
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9
Q

What were physicians?

A
  • Medically trained at university
  • Diagnosed illnesses and gave treatments or send patients to an apothecary or barber surgeon
  • Urine charts, astrology used
  • Expensive, mostly used by wealthy
  • Very few of them
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10
Q

What gave care in the home?

A
  • Most people were treated at home by female family member
  • The village ‘wisewoman’, would also tend to people in their homes for free
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11
Q

How did physicians treat patients?

A
  • Observe the patient’s symptoms and check their pulse, skin colour, urine
  • Consulted urine charts in their vademecum
  • Consultant Zodiac charts
  • Then either treated patients themselves or sent them to an apothecary or barber surgeon
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12
Q

What were the features of hospitals in the Middle Ages?

A
  • Many were places where travellers and pilgrims stayed on their journeys
  • Patients and surroundings were kept very clean
  • They were places of recuperation rather than where patients were treated for disease
  • Patients were given fresh food and plenty of rest
  • Usually people with infectious diseases were not admitted
  • Some were built for specific infectious diseases
  • Many were run by the church
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13
Q

How did people think the black death was caused?

A
  • Religion – God sent the plague as punishment for people sins
  • Astrology – the position of Mars, Jupiter and Saturn was unusual at this time
  • Miasma – bad air or smells caused by decaying rubbish
  • Volcanoes – poisonous gases from European volcanoes and earthquakes carried in the air
  • Four humours – most physicians is believed that disease is caused by an imbalance in four humours
  • Outsiders – strangers or witches had caused the disease
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14
Q

How did people try to avoid catching the Black Death?

A
  • Praying and fasting – people believed God caused the disease, so tried to show god they were sorry by punishing themselves
  • Clearing up rubbish in the streets
  • Smelling toilets or other bad smells, believed it would overcome the plague
  • Lighting a fire in the room, ringing bells, having birds fly around the room for air circulation
  • Carrying herbs and spices to avoid breathing bad air
  • Not letting unknown people enter the town
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15
Q

What were the symptoms of the Black Death?

A
  • Swelling of the lymph glands into large lumps filled with pus (buboes)
  • Fever and chills
  • Headache
  • Vomiting, diarrhoea, abdominal pain
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16
Q

What were the treatments for the Black Death?

A
  • Praying and holding lucky charms
  • Cutting open buboes to drain the pus
  • Holding bread against the buboes then burying it in the ground
  • Eating cool things and taking cold baths
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17
Q

How did the work of physicians change in the renaissance?

A
  • As fewer people believed astrology caused disease, physicians stopped using astrology charts
  • Due to improved knowledge of digestion, physicians realised that urine was not a good indicator of disease and stopped using urine chats
  • They carried out more direct observations rather than relying on the patient explaining their symptoms
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18
Q

Who was Thomas Sydenham?

A
  • He worked as a doctor during the 1660s and 70s
  • In 1676 he wrote his book, Observationes Medicae
  • Nicknamed ‘English Hippocrates’
  • He didn’t rely on medical books when diagnosing, instead he recorded symptoms
  • Believed disease wasn’t related to the nature of the person who had it
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19
Q

How did the printing press promote change?

A
  • Invented in 1440 by Gutenberg
  • By the start of the Renaissance, there were hundreds of printing presses across Europe
  • It meant that many exact copies could be produced in a short amount of time
  • The ideas and discoveries of scientists and doctors could be shared more effectively and much faster
  • It reduced the churches control of ideas, it couldn’t prevent the publication of ideas it didn’t approve of
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20
Q

What was the Royal Society?

A
  • They met for the first time in 1660
  • It recorded the results of experiments and sponsored scientists to enable them to carry out research
  • In 1662 it received a royal charter from Charles II, this gave them credibility and raised their profile
  • In 1665 they published a journal called Philosophical Transactions, it meant that scientists could build on each other’s work
  • It encouraged members to write reports in English instead of Latin, and in straightforward language to make it accessible for everyone
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21
Q

How did hospitals change in the Renaissance?

A
  • Used less for travellers and more for sick people
  • Many had their own apothecary and physicians frequently visited
  • In 1536, the dissolution of the monasteries caused most hospitals to close
  • It wasn’t until well into the 1700s that the number of hospitals returned to pre-dissolution levels
  • More pest houses appeared, where people with contagious disease went for care
  • When hospitals did reappear, they were run by physicians who focused on treating the sick rather than religion
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22
Q

What were some changes in prevention and treatment in the Renaissance?

A
  • More emphasis on removing miasma, by removing sewage and rubbish
  • People regularly change the clothes to keep clean instead of just bathing
  • Herbal remedies from newly discovered countries appeared in England, and some were effective
  • The theory of transference led people to rub objects on themselves to try and transfer the disease to the object
  • Alchemy caused chemical cures using metals or minerals to become popular
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23
Q

In what ways did the training for apothecaries and surgeons stay the same in the renaissance?

A
  • They were still not giving university training
  • They were still seen as inferior to physicians and they were cheaper
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24
Q

In what ways did the training for physicians stay the same in the renaissance?

A
  • They were still trained at universities and the training lasted for many years
    - Training was still based on learning from textbooks rather than practical experience
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25
Q

In what ways did the training for apothecaries and surgeons change in the Renaissance?

A
  • Both were better trained through being in guild systems, where they were apprentices > journeyman > masters
  • A license was now needed, these were only issued after complete training
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26
Q

In what ways did the training for physicians change in the Renaissance?

A
  • There was a wider variety of medical books and detailed drawings due to the printing press
  • New ideas about anatomy inspired some physicians to become more practical and experimental
  • Dissection was legalised but took time to become commonplace
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27
Q

Who was Andreas Vesalius?

A
  • He carried out a large number of dissections of human bodies
  • He published his book, ‘On the fabric of the human body’, in 1543
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28
Q

What was the importance of Vesalius?

A
  • Made study of anatomy fashionable, it became central to study of medicine
  • Proved some of Galen’s work incorrect, this encouraged others to question Galen’s theories
  • He encouraged others to carry out dissections
  • His work was widely published in England, his illustrations of the human body were copied into other medical textbooks
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29
Q

When was the Great Plague?

A

1665

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30
Q

How did people’s ideas about what caused the plague change during the great plague?

A
  • Miasma, this was the most common belief
  • Fewer people believed it was caused by an imbalance in the four humours
  • People knew that disease could be passed from person to person
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31
Q

How did people try and treat the Great Plague?

A
  • Herbal remedies, either mixed in the home bye-bye apothecaries and ‘quack’ doctors
  • The theory of transference meant people tried to transfer the disease to other objects, especially birds
  • People believed you could sweat the disease out, so sufferers were wrapped up and put by a fire
32
Q

How did the government try to prevent the Great Plague from spreading?

A
  • Theatres were closed and large gatherings were banned
  • Dogs and cats were killed
  • Barrels of tar were burned in the streets
  • Every day, carts collected the dead then buried them in deep mass graves
  • Household was boarded into its home for 40 days, or taken to a pest house
  • Days of fasting and public prayers were ordered
33
Q

Who was William Harvey?

A
  • Was a lecturer of anatomy at a College of physicians
  • Carried out public dissections
  • Taught the importance of observing symptoms, rather than relying on textbooks for diagnosis
  • Published, ‘an anatomical account of the motion of the heart and blood in animals’, in 1628, it contained detailed drawings
34
Q

What did William Harvey discover about the circulation of blood?

A
  • He researched Vesalius’ theory that blood flow towards the heart, he proved this right by using a dissected body and pumps to show blood only flowed one way
  • He then proved that blood could not be produced by the liver and absorbed into the body, as Galen had thought
  • He was influenced by new technology, such as mechanical water pumps, which made him think the way human bodies work in a similar way
  • He discovered the arteries and veins were part of one system and that blood was pumped around the body by the heart
35
Q

What was the importance of William Harvey?

A
  • He proves some of Galen’s theories wrong, making people question his other theories
  • By 1700 his work was being taught in medical schools
  • As a royal physician, Harvey’s work gained publicity and credibility
  • His scientific methods of observation and use of dissection had brought results, so were copied by others
  • His discoveries left many unanswered questions which encouraged further experiments
36
Q

What was the theory of spontaneous generation?

A

Germs were produced by decaying matter

37
Q

How did microscopes change medicine in the 18th and 19th century?

A
  • By 1700, Max games have developed cloudy images of bacteria or germs
  • By 1850, microscopes had further improved so that tiny images could be seen clearly
38
Q

What was the germ theory?

A
  • In 1861, Louis Pasteur (a French chemist) published his germ theory
  • This proved spontaneous generation was incorrect
  • He proved that microbes in the air cause decay, he discovered this when investigating why liquids turned sour in the the brewing industry
  • He also theorised that germs cause disease but was unable to prove this
39
Q

What role did Robert Koch have in developing the germ theory?

A
  • Koch (a German doctor and scientist) read Pasteur’s work and proved him right
  • He identified the specific microbes that caused TB in 1882, and cholera in 1883
  • He developed an easier way of growing bacteria on agar jelly
  • He also discovered that chemical dyes stained bacteria, making them easier to see under a microscope
  • Other scientists then used these methods to identify the microbes that caused other diseases
40
Q

Who was Florence Nightingale and how did she improve hospital care?

A
  • Little training for female nurses
  • Attended the first nurses training school in Germany
  • Was asked to lead a team at a military hospital during the Crimean war
  • Believed in Miasma so promoted hygiene, fresh air and good supplies for nurses
  • She published books on nursing and set up a training school for nurses
41
Q

What were the changes in hospital care during the 18th and 19th century?

A
  • The first cottage hospital (nurses gave care and GPs prescribed home treatments) opened in 1859
  • Hospital cleanliness and organisation improved, due to Nightingale and Pasteur
  • Specialist hospitals, like asylums for mentally ill and fever houses for infectious diseases
  • Public pressure led to infirmaries being set up for the poorest in society
42
Q

What different substances were used for anaesthetics during the 18th and 19th century?

A
  • Before 1800, alcohol and opium had little success easing pain in operations
  • In 1844 laughing gas was used in dentistry, but failed to ease pain and patients remained conscious
  • From 1846 ether It made patient totally unconscious and lasted a while, however it made them cough during and sick afterwards
  • From 1847 chloroform (discovered by James Simpson) was very effective with few side-effects, however it was hard to get the dose right and could kill people because of the effect on the heart
  • In 1884 cocaine was used as the first local anaesthetic, in 1905 a less addictive version (novocaine) was used
43
Q

How did Joseph Lister develop antiseptics?

A
  • In 1861 half the patients in surgery die from post-operative infections, Lister starts work as a surgeon
  • In 1864 Lister reads Pasteur’s germ theory and learns that carbolic acid kills parasites in sewage
  • In 1865 Lister soaks bandages in carbolic acid to avoid infected wounds
  • In 1866 Lister uses carbolic acid to clean wounds and equipment and invents a spray to kill germs in the air
  • In 1867 Lister states that his wards have been infection-free for nine months, he publishes his ideas
44
Q

What opposition was there to anaesthetics?

A
  • People are worried about the long-term effects
  • They thought being unconscious made patients more likely to die
  • The Victorians were very religious and thought God inflicted pain for a reason, so it was wrong to interfere with this pain
45
Q

What role did Louis Pasteur have in vaccinations?

A
  • Pasteur’s team of scientists discovered that a weakened version of a disease-causing microbe could be used to create immunity from that disease
  • Pasteur developed vaccines against anthrax and chicken cholera for animals, and against rabies for humans
46
Q

What were the reasons for the public health act 1875?

A
  • The government had a laissez-faire approach to public health
  • During the 19th century several academics (especially cholera) caused the government’s attitude to change
  • Also the increasing number of men who could vote influenced politicians
  • By 1875 people recognised that it was the government’s responsibility to improve living conditions in cities
47
Q

What did the public health act 1875 state?

A

City authorities must provide:
- Clean water
- Sewers
- Public toilets
- Street lighting
- Public parks
Also:
- Inspect lodging houses for cleanliness
- Monitor the building of new houses to prevent damp and overcrowding
- Check the quality of food sold in shops
- Employ a public health officer to monitor disease

48
Q

How did Edward Jenner discover a vaccine for smallpox?

A
  • Since the 1720s doctors had been inoculating people against smallpox with a mild version of disease
  • Jenner regularly treated people for the mild disease, cowpox, and noticed that these people never caught smallpox
  • In the 1790s he tested his theory by infecting local people with cowpox then infecting with smallpox, none caught smallpox
49
Q

What effects did Jenner’s discovery have on society?

A
  • In 1798 the Royal Society refused to publish his ideas ideas, so he paid to print his findings which included instructions so others could follow
  • By 1800 around 100,000 people worldwide had been vaccinated, but it took time to be popular in Britain
  • In 1802 the Royal Jennerian society was set up to promote the vaccination
  • In 1840 vaccinations were provided for free to the poor
  • In 1853 vaccinations were made compulsory
  • By 1979 smallpox had been wiped out
50
Q

Why was there opposition to Jenner?

A
  • People thought it was wrong to give people and animals disease
  • It interfered with God’s plan
  • Doctors lost money when the government offered free vaccination
  • Some doctors didn’t vaccinate properly so it didn’t work
51
Q

What was cholera?

A
  • Mostly affected the poorest slum areas of cities
  • Causes severe diarrhoea and vomiting, leading to dehydration
  • In the early 19th century there was no treatment and most people who caught it died
52
Q

What did John Snow do?

A
  • He observed the cholera epidemic of 1848-49 and began his theory that cholera was spread through contaminated drinking water
  • When cholera broke out again in 1854 in Soho he mapped all the deaths and found a strong link to one water pump on Broad Street
  • He removed the handle from the pump so people couldn’t collect water and the number of deaths fell dramatically
  • It was later discovered that a cesspit close by was leaking water into the water
53
Q

What was the significance of Jon Snow’s work?

A
  • Many cholera deaths in Soho were prevented
  • As the Germ theory hadn’t yet emerged, the government didn’t act on Snow’s recommendation to build a new sewer system
  • Snow‘s work later, combined with other evidence, meant a new London sewer system was completed in 1875
  • This link between between dirty water and disease led to the public health act in 1875 when authorities were finally forced to provide clean water
54
Q

How did the understanding of genetics change in modern Britain?

A
  • Mendel showed how characteristics are passed between generations
  • New technology (electron microscopes, x-rays) let scientists discover that every cell in the body contains DNA
  • James Watson and Francis Crick worked together on how genetic codes of DNA fitted together
  • They analysed x-ray crystallography by Marice Wilkins and Rosalind Franklin at Kings College Hospital
  • In 1953 they worked out the double helix structure
  • In 1990 James Watson led the Human Genome project and started mapping out every gene in human DNA
55
Q

What were the effects of understanding genetics better?

A
  • A better understanding of some genetic conditions, such as Down’s syndrome
    - Predicting whether individuals are at higher risk of cancer
  • The discovery that stem cells can be grown into different cells
56
Q

What are some examples of technology used in modern Britain medicine?

A
  • Microscopes
  • Incubators
  • X-rays
  • Prosthetic limbs
  • MRI, CT, ultrasound scans
  • Endoscopes
  • Pacemakers
  • Dialysis machine
  • Insulin pumps
  • Blood sugar and blood pressure monitors
  • Hypodermic needles
57
Q

How were magic bullets discovered?

A
  • Paul Ehrlich and his team, helped by German government, tested many compounds of Salvarson (arsenic) to find one to cure syphilis
  • In 1909 Dr Hata joined the team and discovered they had rejected a compound that worked, the 606th
58
Q

Who discovered blood groups? What year? Importance?

A
  • Karl Landsteiner
  • 1901
  • In 1902 his colleagues found a fourth group
  • Made transfusions successful
59
Q

What were some ways that enabled diagnosis to improve in modern Britain?

A
  • Blood tests – tested for many conditions without invasive diagnosis methods, 1930s
  • Blood sugar monitoring – so diabetes sufferers can manage their condition, 1960s
  • Blood pressure monitor – to diagnose high and low bread pressure, 1880s
  • Endoscopes – to investigate digestive symptoms and assist treatment by carrying surgical instruments into the body, 1900s
  • Electrocardiograms – use electrical impulses to track heart activity, 1900s
60
Q

What were some developments in scanning techniques in modern Britain?

A
  • X-rays – to see inside human body without cutting into it, diagnosed broken bones etc, 1890s
  • MRI scans - use radio waves and magnets to identify soft tissue damage in the brain and heart, 1970s
  • CT - combines X-rays to identify tumours, 1970s

- Ultrasound – use sound waves to build a picture, can diagnose kidney stones, 1940s

61
Q

What did the first magic bullet lead to?

A
  • In 1932, Gerhard Domagk developed the second magic bullet, Prontosil, which cured some types of blood poisoning
  • Other scientists found that sulphonamide in Protosil also cured pneumonia, scarlet fever, and meningitis
62
Q

What caused the NHS to be set up?

A

The 1942 Beveridge Report recommended it

63
Q

How was the NHS funded and set up?

A
  • Paid for by national insurance contributions, taking from wages
  • Took over existing hospitals and medical services
  • The government was now responsible for 1143 voluntary hospitals and 1545 city Hospitals
64
Q

What problems did the NHS face?

A
  • Post-war Britain didn’t have a lot of money to spend on medical care
  • Many hospitals were built in the 19th century so needed updating
  • Many GPs needed modernisation
65
Q

When was the diphtheria vaccination campaign? (give more details)

A
  • 1942
  • Children immunised in WW2
  • First national vaccination campaign
  • 3000 children died a year
66
Q

When was the Polio vaccination? (give more details)

A
  • 1956
  • 8000 cases reported each year in Britain
  • Successful - last person to get it in Britain was in 1984
67
Q

When were the clean air acts? Why were they put in place?

A
  • 1956 and 1968
  • To prevent the spread of smog in London
68
Q

When was the Health Act that banned smoking in public places?

A
  • 2006
  • But didn’t come into effect until 2007
69
Q

What were the stages of the discovery of penicillin?

A
  • In 1928 Alexander Fleming noticed bacteria in a petri dish was killed by penicillin mould
  • In 1929 and published his findings but he didn’t believe it would work on living people as it was ineffective when mixed with blood
  • In 1939 Florey and Chain continued his research
  • In 1940 they tested penicillin on infected mice and it was successful
  • In 1941 it was first tested on a human with blood poisoning , it proved effective but they ran out of penicillin so he died anyway
70
Q

What were the stages of mass-producing penicillin?

A
  • Florey asked UK drug companies but they were busy producing chemicals for WW2
  • In July 1941 Florey asked US drug companies, they agreed but on a small scale
  • After US joined WW2 the government funded 21 drug companies to mass-produce it in 1942
  • In 1943 UK drug companies also started to mass-produce it
  • By D-Day in June 1944 there was enough penicillin to treat all Allied casualties (2.3 million doses)
  • In 1945, Hodgkin identified the chemical structure of penicillin, leading to synthetic versions being produced
71
Q

How many people are diagnosed with lung cancer each year?

A

Over 40,000

72
Q

How is technology used to diagnose lung cancer?

A
  • In the past x-rays were used but they weren’t detailed enough for accurate diagnosis 
  • Today CT scans are used which create a more detailed picture
73
Q

How is the science and technology used to treat lungs cancer?

A
  • Radiotherapy, to shrink or prevent growth of a tumour
  • Chemotherapy, used since 1970s, injected with many different drugs to shrink the tumour before surgery
  • Transplants, cancerous lungs can be replaced with lungs from an organ donor
  • Genetic research, some chemotherapy drugs work better for tumours with a certain genetic mutation
74
Q

What are the problems with diagnosing lung cancer?

A
  • Often not detected until it is very advanced so can’t be treated
  • No national screening program, people are not routinely tested as tests are not accurate enough to outweigh the negative effects
75
Q

How has the UK government tried to prevent lung cancer?

A
  • TV advertising for cigarettes banned in 1965
  • Tax on tobacco products is regularly increased
  • In 2007 smoking was banned in public places and the legal age for buying raised from 16-18
  • In 2012 all cigarette products in shops are covered
  • In 2015 smoking ban in cars carrying children under 18