Medicine

Question 1

Auer Rods

Answer 1

AML

Question 2

Philadelphia chromosome

Answer 2

CML

Question 3

most common leukaemia in children

Answer 3

ALL

Question 4

70 y/o, weight loss, painless lymphadenopathy, lymphocytosis

Answer 4

CLL. Can transform to Richter’s syndrome.

Question 5

60 y/o, abdo pain, massive splenomegaly, weight loss/tired/night sweats, WCC RAISED

Answer 5

CML

Question 6

Child: easy bruising, infections, hepatosplenomegaly, pancytopenia

Answer 6

ALL

Question 7

smear cells

Answer 7

CLL

Question 8

teardrop cells

Answer 8

myelofibrosis

Question 9

Pt has blood transfusion –> 30min later has fever, hypotensive, red coloured urine. What rxn is going on?

Answer 9

Immediate haemolytic transfusion rxn

Question 10

fever, muscle pain, loss appetite, N&V. slow pulse & high temp. Dx?

Answer 10

Yellow fever

Question 11

alpha feta protein: tumour marker for ?

Answer 11

hepatocellular carcinoma (liver ca)

Question 12

4 y/o, lymphadenopathy, febrile, sore throat, palpable liver edge. Dx?

Answer 12

ALL

Question 13

10 y/o: marble like swellings over armpits & neck. Not painful. Dx?

Answer 13

non Hodgkin’s lymphoma

Question 14

1st line Tx for absence seizure

Answer 14

sodium valproate

Question 15

Is PSC associated w UC or Crohn’s?

Answer 15

UC

Question 16

45 y/o, jaundice, xanthelasma, skin excoriation. Raised ALP, slightly raised AST, ALT. +ve for AMA M2 abs. ?Dx

Answer 16

PBC

Question 17

causative agent for travellers’ diarrhoea?

Answer 17

E coli

Question 18

What is pellagra and what are its symptoms?

Answer 18

Lack of niacin.
Dementia, diarrhoea, dermatitis

Question 19

45 y/o - palppitations, dizziness, SOB. Sx associated w change in position. S1 pansystolic mumur @ apex. Dx?

Answer 19

atrial myxoma

Question 20

65 y/o. PMH: DM, IHD. Has soft early diastolic murmur best heard at L parasternal edge on expiration. ?dx
Collapsiing pulse/wide pulse pressure.

Answer 20

aortic regurgitation

Question 21

14 y/o boy, reports: clumsy in morning spilling cereal, daydreaming, sometimes uncontrollably jerky. Dx?

Answer 21

Janz syndrome (juvenile myoclonic epilepsy)
generalised seizure on waking, daytime absences, myoclonic

Question 22

STEMI treatment. No PCI available - what is the medical mx?

Answer 22

ticagrelor + aspirin.
or clopidogrel + aspirin or clopi alone - if high risk bleeding

Question 23

STEMi treatment. Pt having PCI - what to give?

Answer 23

prasugrel + aspirin.

Question 24

STEMI treatment. Pt having PCI, BUT has had prev stroke. What to give?

Answer 24

clopidogrel + aspirin.
Prasugrel is contraindicated in prev stroke

Question 25

skin condition: ankles/elbows, associated w coeliac disease?

Answer 25

dermatitis herptiformis

Question 26

ObG: Gestational sac >25mm with no fetal pole = what kind of miscarriage?

Answer 26

missed miscarriage

Question 27

35 y/o M - aki, haemoptysis, fever. Anti- GBM abs. Dx?

Answer 27

Good pasture's

Question 28

abs associated w antiphospholipid syndrome?

Answer 28

anti-cardiolipin

Question 29

what is erysipelas? RF? how to treat?

Answer 29

superficial skin infection. DM. Penicillin.

Question 30

when to transfuse platelets?

Answer 30

platelets <50

Question 31

When to give FFP?

Answer 31

when PT is >1.5x normal

Question 32

WHen to give prothrombin complex concentrate?

Answer 32

when patient has been on warfarin and there is no time to reverse it

Question 33

Greek man, Heinz bodies, +ve Beutler test = dx?

Answer 33

G6PD

Question 34

what are heinz bodies? what might it indicate?

Answer 34

denatured Hb - indicative of haemolysis e.g. G6PD, thalassaemia, haemolytic anaemia

Question 35

Pt: DM, sudden painless loss of vision in L eye. Pale, swollen optic disc. Dx?

Answer 35

AION (anterior ischaemic optic neuropathy)

Question 36

what abx can cause achilles tendionpathy?

Answer 36

fluoruquinolones - e.g. ciprofloxacin

Question 37

20 yr old - anal pain on and after defecation. blood on wiping. dx?

Answer 37

anal fissure

Question 38

GU clinic: male has itchy penis, no discharge. Doesn't use condoms. Tx? GU clinicl: male has purulent discharge, dysuria. Dx?

Answer 38

Chlamydia --> azithromycin IM or doxy BD gonorrhoea --> azithromycin + cefotaxime

Question 39

How is SCLC often treated?

Answer 39

chemo, radio not as effective in NSCLC

Question 40

what is the treatment for polycythaemia vera?

Answer 40

asymptomatic: venesection, aspirin symptomatic: immunosuppression