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CHEMISTRY > Medicinal - Enzymes/Proteins > Flashcards

Medicinal - Enzymes/Proteins Flashcards

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1
Q

How does secondary structure form?

A

Hydrogen Bonding within the polypeptide chain.

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2
Q

How does tertiary structure form?

A

Intermolecular forces between the side chains/residual groups. eg HB, DP-DP and Dispersion… or Disulfide bridges if 2 x -SH (cysteine) side chains present.

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3
Q

Why may a drug not work?

A

Bc different spatial arrangement around the chiral C is not s+c to the enzymes active site. Hence ineffective inhibitor.

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CHEMISTRY (7 decks)

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