Medicinal chemistry of antihormonal agents Flashcards

1
Q

What drugs inhibit estrogen biosynthesis?

A

Letrozole, Anastrozole, Exemestane

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2
Q

What is Abiraterone used for and what is it’s mechanism of action?

A

Used for prostate cancer

It inhibits cell poliferation by inhibition of CYP17 hydroxylase and lyase activity

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