Medicinal chemistry of antihormonal agents Flashcards
1
Q
What drugs inhibit estrogen biosynthesis?
A
Letrozole, Anastrozole, Exemestane
2
Q
What is Abiraterone used for and what is it’s mechanism of action?
A
Used for prostate cancer
It inhibits cell poliferation by inhibition of CYP17 hydroxylase and lyase activity