Medications That Cause Obesity Flashcards

1
Q

Preferred antidepressants with less weight gain

A

Bupropion
SNRIs
SSRIs other than Paroxetine
Nortryptiline

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2
Q

Effects of Trazodone

A

Low risk

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3
Q

Before blaming weight gain on a medication they are taking with weight gain potential, what do you need to do

A

Get a timeline of onset to determine if initiation of the medication matches onset of weight changes

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4
Q

Effects of Atenolol

A

Weight gain

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5
Q

Effects of DPP4 (Januvia/Sitagliptan, Onglyza/Saxagliptan, Tradjenta/Linagliptan…)

A

Weight negative

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6
Q

Effects of sedative hypnotics (Ambien etc.)

A

Weight gain

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7
Q

Effects of Depo

A

Weight gain

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8
Q

The medication with best evidence for use to reverse antipsychotic associated weight gain

A

Metformin

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9
Q

Worst antipsychotic for weight gain

A

Olanzapine

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10
Q

Effects of Sulfonylureas (Glimepiride, Glipizide, Glybyride…)

A

Weight gain

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11
Q

Diabetic meds with more weight gain

A
Insulin
Sulfonylureas
Thiazolidinediones
Gabapentin
Lyrica
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12
Q

Effects of Metformin

A

Weight negative

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13
Q

Effects of Doxepin

A

Weight gain

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14
Q

Effects of Amitriptyline

A

Heavy weight gain

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15
Q

Antidepressants with more weight gain

A

Paroxetine
Amitryptiline
Doxepin
Mirtazipine

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16
Q

Effects of prednisone

A

Moderate weight gain

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17
Q

Effects of carbamazepine

A

Low risk

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18
Q

Effects of diphenhydramine

A

Weight gain

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19
Q

Effects of Respiradone

A

Weight gain

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20
Q

Worst diabetic Med for weight gain

A

Insulin

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21
Q

Effects of Thiazolinediones (Actos/Pioglitazone…)

A

Weight gain

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22
Q

Effects of OCPs

A

Low risk

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23
Q

Effects of Lithium?

A

Heavy weight gain

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24
Q

Effects of some chemotherapeutics

A

Weight gain

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25
Q

Effects of Clonidine

A

Weight gain

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26
Q

Diabetic meds with weight loss

A
Metformin
GLP-1
SGLT-2s
DPP-4s
Acarbose
Amylin analogs
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27
Q

If gain weight from a medication, will stopping it reverse weight gain

A

Sometimes it won’t. Need extra interventions

28
Q

Effects or Nortriptyline

A

Low risk

29
Q

Strength of evidence for weight gain related to medication use

A

Weak. Usually observational studies not RCTs. Studies have contradictory outcomes. No head to heads. Report average which complicates things for meds that may have highly variable effect.

30
Q

Effects of Ziprasidone

A

Low risk

31
Q

Effects of Metoprolol

A

Weight gain

32
Q

Effects of Paroxetine

A

Heavy weight gain

33
Q

Effects of Nexplanon

A

Low risk

34
Q

Antipsychotics with less weight gain

A

Aripiprazole
Ziprasidone
Haloperidol

35
Q

Effects of Valproate

A

Heavy weight gain

36
Q

Seizures meds with less weight gain

A

Topiramate
Lamotrigine
Carbamazepine

37
Q

Effects of Mirtazipine

A

Heavy weight gain

38
Q

Effects of dextromethorphan (Robitussin)

A

Can cause weight loss

39
Q

Effects of IUDs

A

Low risk for hormonal

Lower risk for copper

40
Q

Effects of GLP-1s (Victoza/Liraglutide, Byetta/Bydureon/Exenatide, Trulicity/Dulaglutide …)

A

Weight negative

41
Q

Seizure meds with more weight gain

A

Valproate

Gabapentin

42
Q

Effects of Bupropion

A

Weight negative

43
Q

Effects of SGLT-2s (Invokana/Canagliflozin, Jardiance/Empagliflozan…)

A

Weight negative

44
Q

Least obesogenic antipsychoatic

A

Ziprasidone

45
Q

Effects of SNRIs

A

Low risk

46
Q

Effects of SSRIs

A

Low risk weight gain (except for Paroxetine)

47
Q

Effects of Loratidine

A

Minimal weight gain

48
Q

Effects of Gabapentin

A

Moderate weight gain

49
Q

Effects of Amlodipine

A

Weight gain via edema

50
Q

Effects of Lyrica

A

Worse than Gabapentin

51
Q

Effects of Benzos

A

Low risk of weight gain

52
Q

Mood stabilizers with more weight gain

A

Lithium

Valproate

53
Q

Effects of Olanzapine

A

Heavy weight gain

54
Q

Effects of Lamotrigine

A

Low risk

55
Q

Effects of opioids

A

Weight gain

56
Q

Effects of Topiramate

A

Weight negative

57
Q

Effects of testosterone

A

Weight negative

58
Q

Effects of Haloperidol

A

Low risk

59
Q

Effects of Aripiprazole

A

Low risk

60
Q

Effects of Carvedilol

A

Weight neutral

61
Q

Effects of HIV retrovirals

A

Weight gain

62
Q

Preferred mood stabilizers with less weight gain

A

Lamotrigine

Carbamazepine

63
Q

Effects Quetiapine

A

Moderate Weight gain

64
Q

If seeing weight gain with a medication that you can’t stop because it’s critical, what next step should you consider

A

Decreasing dose. Weight gain is often weight dependent

65
Q

Antipsychotics with more weight gain

A

Olanzapine
Clozapine
Respiradone
Quetiapine

66
Q

Effects of Clozapine

A

Heavy weight gain