Medications in pregnancy Flashcards
1
Q
What are the possible fetal complications of fetal exposure to warfarin in 1st trimester?
A
Warfarin embryopathy
- midfacial & limb hypoplasia
- Stippled bone epiphyses
2
Q
What are the features associated with ACE inhibitor fetopathy?
A
- oligohydramnios
- IUGR
- hypocalvaria (skull bones incompletely formed)
- renal failure
- death
3
Q
What are the congenital malformations associated with retinoic acid?
A
- CNS anomalies
- Craniofacial anomalies
- Branchial arch anomalies
- CVS anomalies (usually conotruncal defects & aortic arch abnormalities)