Medications

Question 1

Ozempic (Semalglutide)

Answer 1

GLP-1

• Contraindicated for medullary thyroid cancer
• Reduction in cardiac events

Question 2

Forxiga (Dapaginozin)

Answer 2

SGLT-2 Inhibitor

- not to be used with bladder cancer

Question 3

Actos (Pioglitazone)

Answer 3

Thiazolidinedione

- Enhances insulin sensitivity

Question 4

Januvia (Stialiptin)

Answer 4

DPP-4 Inhibitors

- caution in GFR <50

Question 6

Diabeta (Glyburide)

Answer 6

Sulfonylurea - Insulin Secretagogue

• Possible increase in CV risk
• Stimulates endogenous insulin secretion

Question 7

Adlxyn (Lixisenatide)

Answer 7

GLP-1 Agonist

- contraindication in thyroid cancer

Question 8

Victoza (Liraglutide)

Answer 8

GLP-1 Agonist

- Contraindicated in thyroid cancer

Question 9

Gluconorm (Repaglinide)

Answer 9

Meglitinide - Insulin Secretagogue

• stimulates endogenous insulin secretion
• Not recommended for eGFR <60

Question 11

Invokana (Dapaginozin)

Answer 11

SGLT-2 Inhibitor

- black box warning for lower limb amputations

Question 13

Byetta (Exenatide)

Answer 13

GLP-1 Agonist

- contraindicated with thyroid cancer

Question 15

Jardiance (Empagliflozin)

Answer 15

SGLT-2 Inhibitor

Question 16

Avandia (Rosiglitazone)

Answer 16

Thiazolidinedione

• Enhances insulin sensitivity in peripheral tissues and liver
• controversy regarding MI risk

Question 17

Onglyza (Saxagliptin)

Answer 17

DPP-4 Inhibitor

- caution in those with HF

Question 18

Bydureon (Exenatide)

Answer 18

GLP-1 Agonist

- contraindicated in thyroid cancer

Question 19

Trajenta (Linagliptin)

Answer 19

DPP-4 Inhibitor

- may be used in GFR <20

Question 20

Trulicity (Dulaglutide)

Answer 20

GLP-1 Agonist

- contraindicated in thyroid cancer

Question 21

-tide

Answer 21

GLP-1 Agonist

Question 23

-ide

Answer 23

Insulin Secretagogue

• Sulfonylurea
• Meglitinides

Question 24

-zone

Answer 24

Thiazolidinedione

Question 25

Acarbose (Glucobay)

Answer 25

Alpha-Glucosidase Inhibitor

• Inhibits enzymes that break down sugar
• Treat lies with dextrose or milk lactose

Question 26

-liptin

Answer 26

DPP-4 Inhibitor

Question 27

-ozin

Answer 27

SGLT-2 Inhibitor

Question 28

Nesina (Alogliptin)

Answer 28

DPP-4 Inhibitor

Question 32

Metformin (Glucophage)

Answer 32

Biguanide

• Contraindicated in eGFR < 30
• Reduce MI
• Not to be used with excessive alcohol use

Question 33

Diamicron (Glicaside)

Answer 33

Sulfonylurea - Insulin Secretagogue | - stimulates endogenous insulin secretion

Question 34

ACE/ARB

Answer 34

Clinical CVD Age >55 years with additional CV risk factor or end organ damage Microvascular complications Not to be used in pregnancy

Question 35

ASA Therapy

Answer 35

In people with established CVD or with risk factors as prevention

Question 36

Statins

Answer 36

Clinical CVD Age >40 Age <40 with; diabetes duration >15 years and age >30, microvascular complications, other CV risk factors

Question 37

Pregnancy

Answer 37

Stop: ACE, ARB, Statins, Fibrates, Gabapentin Avoid while breastfeeding: TZD, GLP-1, SGLT-2, DPP-4 - metformin and glyburide may be used

Question 38

SADMANS

Answer 38

``` Sulfonylureas ACE Inhibitors Diuretics, Direct renin inhibitors Metformin ARBs NSAIDs SGLT-2 Inhibitors ```