Medications Flashcards
What is the difference between chemical, generic and trade names of medications?
Chemical names describe to chemical components of the medication
Generic names are the name of the active ingredient, given by the first manufacturer
Trade names are given by manufacturers of subsequent variants of the same medication
What are the different forms medication can come in?
- aerosol spray / foam
- aqueous solution
- aqueous suspension
- caplet
- capsule
- cream
- elixer
- extract
- gel/jelly
- linament
- lotion
- lozenge
- ointment (salve, unction)
- paste
- pill
- powder
- suppository
- syrup
- tablet
- tincture
- transdermal patch
What laws govern medications in Western Australia?
- Therapeutic Goods Act 1989 (Commonwealth)
- Therapeutic Goods Regulations 1990 (Commonwealth)
- Narcotic Drugs Act 1967 (Commonwealth)
- Poisons Act 1964 (WA specific)
- Poisons Regulations 1965 (WA specific)
What are the Schedules of drugs in Australia?
- Schedule 1: not currently in use
- Schedule 2: Pharmacy medicine
- Schedule 3: Pharmacist only medicine
- Schedule 4: Prescription only OR prescription animal remedy
- Schedule 4R: Restricted prescription medicine
- Schedule 5: Caution
- Schedule 6: Poison
- Schedule 7: Dangerous Poison
- Schedule 8: Controlled drug
- Schedule 9: Prohibited substance
- Schedule 10: substances of such danger as to prohibit sale, supply and use
What are the laws around Schedule 8 drugs in hospitals?
- drugs are locked in a cabinet
- special inventory is kept
- two nurses to sign for each administration
- S8 balance is checked each shift (every 8hours)
- all imbalances are investigated
- all discarded doses must be recorded
What are the 6 rights of medication administration?
- right person
- right medication
- right dose
- right time
- right route
- right documentation
What are other medication rights that should be considered outside the 6 rights?
- right education
- right to refuse
- right assessment
- right evaluation
What is the definition of a medication error?
Any preventable event that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of the health care professional, patient, or consumer
What are the consequences of medication errors?
- harm to the patient (up to and including death)
- psychological harm to the medicine administrator
- lost patient and public trust
- monetary costs
What are the most common types of medication errors?
- similar-sounding medication names
- administration without a prescription
- the wrong medication
- the wrong dosage (overdose/underdose)
- the wrong patient
- negligent injection
- failure to note an order change
- failure to administer medication (omission)
- failure to discontinue medication
- use of an unsterile needle
- allergic reactions; and
- failure to assure patient taking medications
How do you calculate the tablets needed?
dose prescribed / stock strength = number of tablets
How do you calculate solution dose volume?
Dose prescribed / stock strength x stock volume = dose volume (mL)
What are the main sources of medication?
Natural
- plants
- animals
- minerals
laboratory synthesis
What needs to be recorded on a Schedule 8 register?
- the name of the patient
- the prescribed drug and dose
- the prescribing doctor’s name
- the date and time of administration
- the signature of two nurses (or a nurse and a doctor) who checked, prepared and gave the drug
- the balance of ampoules/capsules/tablets in supply in the stock cupboard
- wasted or discarded doses
How do you calculate IV rates?
Total volume prescribed (mL) / Infusion time required (hr) = flow rate (mL/hr)
How do you calculate IV rate drop rates?
Total volume prescribed (mL / Infusion time required (min) x drop factor = drops per minute
What are the drop factors for standard clear solution, blood, and paediatric?
standard = 20 blood = 15 paediatric = 60
How do you calculate paediatric doses based on body weight?
child’s dose = child’s weight (kg) x (per kg per day dose prescribed)
What are the common effects of drugs?
- therapeutic effect (aka desired effect) - what the drug is designed to do
- side effect - what the drug also does (eg, nausea)
- adverse effects - severe, unwanted side effects
- drug toxicity - damage caused by overdose, ingested medicines meant for external use, or cumulative effects. Drugs where cumulative toxicity is likely, Therapeutic drug monitoring against international normalised ratio (INR) is required.
- drug allergy - immunological reaction to a medication
- anaphylaxis - severe, life-threatening immunological reaction to medication
- drug tolerance - the need for a higher dose to maintain therapeutic effect
- drug interaction - two drugs interact with each other, causing an effect not seen or intended in each individually
- potentiating effect - a drug interaction that enhances the effect of one or both drugs
- inhibiting effect - a drug interaction that inhibits the effect of one or both drugs
What are the common symptoms of mild drug allergies?
- skin rash
- pruritus (itching)
- angioedema
- rhinitis
- lacrimal tearing
- nausea and/or vomiting
- wheezing and/or dyspnoea
- diarrhoea
What are the two types of drug dependence?
- physiological - when the body (particularly the nervous system) now needs the drug to function normally
- psychological - when the person now needs the drug to maintain a feeling of emotional/mental wellbeing
What is pharmacodymanics?
the process by which the drug changes the body. Drugs may be agonist (causes a reaction) or antagonist (prevents a reaction)
What is pharmacokinetics?
the study of the absorption, distribution, biotransformation and excretion of drugs
What is biotransformation?
AKA detoxification or metabolism, is a process by which a drug is converted to a less active form
What are the different routes of medication administration?
- oral (PO)
- intravenous (IV)
- intramuscular (IM)
- sublingual (subling)
- subcutaneous (subcut)
- rectal
- vaginal
- transdermal
- buccal (cheek)
- topical
- intradermal
- inhalation
What are the advantages of oral medication?
- Most convenient
- Usually least expensive
- Safe, does not break skin barrier
- Administration usually does not cause stress
- Some new oral medications are designed to rapidly dissolve on the tongue, allowing for faster absorption and action
What are the disadvantages of oral medication?
- Inappropriate for people with nausea or vomiting
- Drug may have unpleasant taste or odour
- Inappropriate when gastrointestinal tract has reduced motility
- Inappropriate if a person cannot swallow or is unconscious
- Cannot be used before certain diagnostic tests or surgical procedures
- Drug may discolour teeth, harm tooth enamel
- Drug may irritate gastric mucosa
- Drug can be aspirated by seriously ill people
What are the advantages of sublingual and buccal medications?
- Convenient
- Usually inexpensive
- Safe, do not break skin barrier
- Administration usually does not cause stress
- Drug can be administered for local effect
- More potent than oral route because drug directly enters the blood and bypasses the liver
- Drug is rapidly absorbed into the bloodstream