Medications Flashcards
What SSRI has been shown to be the best choice for pediatric patients?
fluoxetine
UWorld
NMS is more commonly associated with ___ antipsychotics.
first-generation
When is electroconvulsive therapy preferred?
elderly patients unable to eat/drink, psychotic or actively suicidal
What is the treatment for NMS?
bromocriptine or dantrolene
supportive care - hydration andcooling
What is the MOA of bromocriptine or amantadine?
dopaminergic agonists
What is the MOA of dantrolene?
direct-acting muscle relaxant
Ryanodine-Receptor agonist
What is the best medication for treatment resistant schizophrenia?
clozapine
ONLY medication that has evidence that it is superior to others
Which benzodiazepine is safe to use in alcohol withdrawal?
lorazepam
no liver metabolism
Which benzos are long-acting? Are they metabolized by the liver or not?
chlordiazepoxide and diazepam
YES - not safe in pts with possible liver disease
What is benztropine used for?
acute dystonic reaction to antipsychotic EPS
AND
parkinsonism effects of antipsychotic meds
How do you treat parkinsonism effects of antipsychotic medications?
benztropine OR amantadine
What is the MOA of benztropine?
muscarinic agonist
Mercedes-Benz car in Sketchy
How do you treat tardive dyskinesia?
valbenazine
What is the MOA of valbenazine?
monamine transporter 2 inhibitor
A patient on antipsychotic medication is experiencing restlessness and inability to stay still. Treatment?
(Akathisia)
beta blocker
benzo
benztropine
Which second generation antipsychotic is most likely to cause EPS?
risperidone
Which SGA has the highest association with weight gain and metabolic side effects?
olanzapine
vs ziprasidone has low risk profile
What type of therapy is found to be high-yield intervention for schizophrenia?
family therapy and psychoeducation
What is the goal of psychodynamic psychotherapy?
unconver unconscious patterns originating in childhood experiences
Sx: low GFR, nausea, vomiting, diarrhea, confusion agitation, ataxia, tremors/fasciculations
Dx: intoxication of ____
lithium
Treatment for lithium intoxication?
hemodialysis in severe cases
What other medications may increase risk of lithium toxicity?
NSAIDs, thiazide diuretics, ACE-I, tetracyclines, metronidazole