Medications Flashcards
Preferred needle gauge for administering blood products
18G or higher
Maintenance fluid that can be used for blood administration
0.9% NaCl (Normal saline)
Rate used for initial 15 minutes of blood administration
5 mL/min
Blood MUST be administered within how many hours?
4 hours
How frequently should vital signs be checked when administering blood?
Every 15 minutes for at least the first hour
If a transfusion reaction is suspected, the nurse should…
- STOP TRANSFUSION
- Restart NS to maintain IV access
- Bag blood and IV tubing and return to blood bank
- Draw blood samples and collect urine samples
- Monitor for hematuria
What medications can be given for a transfusion reaction?
- Diphenhydramine
- Aspirin
- Steroids
Contraindications to receiving autologous blood
- Acute infection
- Chronic disease
- Hemoglobin less than 11 g/L, hematocrit less than 33%
- Cerebrovascular disease
- Cardiovascular disease
Fluid overload transfusion reaction (S/S and interventions)
- S/S: SOB, rales/crackles
2. Interventions: Administer O2, Slow transfusion, Call MD
Allergic transfusion reaction (Hypersensitivity) (S/S and interventions)
- S/S: Mild = Uticaria, itching, flushing
Anaphylaxis = HypoTN, Dyspnea, low O2, flushing - Interventions: Stop blood, O2, NS, antihistamine
Acute Hemolytic Transfusion Reaction (S/S and interventions)
- S/S (SYSTEMIC): N/V, lower back pain, hypoTN, increase HR, decreased urine, hematuria
- Interventions: Stop blood, airway, antihistamines
Febrile transfusion reaction (most common) (S/S and interventions)
- S/S: Fever, chills, HA, flushing, tachycardia, palpitation
- Interventions: Stop blood, ASPIRIN
Bacterial transfusion reaction (S/S and interventions)
- S/S: Tachycardia, HypoTN, Fever, chills, shock
2. Interventions: Stop blood, obtain culture, antibiotics, steroids
Isotonic solutions
Same concentration as body fluids (no shift of fluids)
- NS
- Lactated Ringers
- D5W
Hypotonic solutions
Concentration less than body fluids (fluid shift to tissues)
1. 1/2 NS
Hypertonic solutions
Concentration greater than body fluids (fluid shift to vessel)
- 10-15% dextrose in water
- 3% NaCl
- Sodium bicarbonate 5%
Main goal of IV therapy
Maintain or restore fluid/electrolyte balance
IV insertion procedure STERILE TECHNIQUE
- Apply tourniquet 4-6” above site
- Clean with alcohol swab working from center outward
- Repeat cleaning with iodine
- Hold skin taunt and stabilize vein
- Insert catheter bevel up at 15-20 degrees
- Lessen angle and advance watching for blood flash
- Once blood is seen, advance another 1/4” and remove tourniquet
- Withdraw needle and advance catheter to hub
- Secure
How frequently should IV tubing be changed?
Every 72 hours
How frequently should IV bags be changed?
Every 24 hours (even if not empty yet)
Infiltration from IV therapy (S/S and interventions)
Medication goes into tissues
S/S: Edema, pain, COOLNESS, decreased flow rate
Interventions: Discontinue IV, WARM compresses, elevate arm
Extravasation from IV therapy (S/S and interventions)
Infiltration with blistering and sloughing of skin
Interventions: Discontinue IV (aspirate as removing), Prevention
Medications that will cause extravasation
- Gentamycin
- Penicillin
- Vancomycin
- Dilantin
- Antineoplastic drugs
- Calcium
- Potassium
- Epinephrine
Phlebitis/Thrombophlebitis from IV therapy (S/S and interventions)
Irritation of the vein
S/S: Reddened, WARM, tender, swelling
Interventions: Discontinue IV, WARM, MOIST compress
Hematoma from IV therapy (S/S and interventions)
S/S: ecchymosis, swelling, leakage of blood at insertion
Interventions: Apply pressure, COOL compress/ICE
Clotting from IV therapy (S/S and interventions)
S/S: Decreased flow rate, back flow of blood into tubing
Interventions: Discontinue IV, Urokinase
Interventions that should NOT be performed if clotting occurs during IV therapy
- Irrigation or milking of tubing
- Increase of IV flow rate
- Aspiration of clot
Length of time a PICC can remain in place
Up to 6 months
S/S to look for to prevent PICC complications
- SOB
- Pain with respiration
- Decreased movement of arm
Length of time a MLC can remain in place
1-8 weeks
Triple lumen catheter lumen uses
- Distal lumen = Infuse or draw blood
- Middle lumen = TPN
- Proximal lumen = Infuse/draw blood, medications
If resistance is met when trying to flush a triple lumen catheter, the nurse should…
Call the HCP. NEVER FORCE FLUSH!!
Dressing change procedure for a triple lumen catheter
- Low-fowler’s
- Masks for both nurse and patient
- Alcohol and iodine to clean site
Adrenergic medications (ENDD)
- Epinephrine
- Norepinephrine
- Dopamine
- Dobutamine
Common side effects of adrenergic medications
- Dysrhythmias
- Tremors
- Anticholinergic reaction (dry mouth, urinary retention)
Nursing interventions for adrenergic medications
- Monitor BP
- Monitor peripheral pulses
- Monitor output
- Maintain safety (can cause drowsiness)
Benzodiazepines medications (Suffix specific)
- PAM or -LAM suffix
* *expect for Chlordiazepoxide
Non-benzodiazepine medications
- Buspirone
2. Hydroxyzine
Herbal antianxiety medications
- Kava
2. Melatonin
Most important to remember for patient taking benzodiazepines
CNS DEPRESSION! (sedation, confusion, hepatic dysfunction) - Avoid alcohol!
Teaching regarding antianxiety medications
- Discontinue slowly (no abrupt stopping)
- Changes in smoking/caffeine intake will affect effectiveness of medication (HX IMPORTANT!)
- Avoid alcohol (CNS depression)
Antacid medications (One word specific)
HYDROXIDE
- Aluminum hydroxide
- Magnesium hydroxide
Side effects of antacids
- Constipation or diarrhea
- Acid rebound between doses
- Metabolic acidosis
Administration timing for antacids
1-2 hours AFTER eating and/or other medications
General side effects of antibiotics
- Allergy (not necessarily after first dose)
- Superinfection
- Organ toxicity (specifically kidney and liver)
General teaching when administering antibiotics
- Take until gone!!
- Always do a culture and sensitivity FIRST before administering
- Encourage fluids (3000 ml/day)
- Generally taken 1 hour BEFORE or 2-3 hours AFTER meals (2 exceptions)
- Check expiration dates! (can be toxic if expired)
Aminoglycoside medications (Suffix specific)
Antibiotics; -MYCIN suffix
**EXCLUDES erythromycin, azethromycin, vancomycin
Aminoglycoside specific side effects
- Ototoxicity (8th cranial nerve)
2. Nephrotoxicity
Cephalosporin medications (Prefix specific)
Antibiotics; CEF-/CEPH- prefix
Cephalosporin specific side effects
- Rash
- Bone marrow suppression
- False positives for protein or glucose in urine
Cephalosporin specific patient teaching
- TAKE WITH FOOD
2. Cross allergy with penicillin
Fluoroquinolone medications (Suffix specific)
Antibiotics; -FLOXACIN suffix
Macrolide medications (exception -mycin’s)
Antibiotic
- Erythromycin
- Azethromycin
Macrolide specific side effects
- Confusion
2. Increased effectiveness of warfarin and theophylline
Penicillin medications (Suffix specific)
Antibiotics; -CILLIN suffix
Penicillin specific side effects
- Breakdown of mouth and GI tract (stomatitis and gastritis)
- Biggest allergy reaction**
Penicillin specific teaching
- Take yogurt or buttermilk if diarrhea develops
2. DON’T double doses if dose is missed
Sulfonamide medications (Prefix specific)
Antibiotics; SULF- prefix
Sulfonamide specific side effects
- Peripheral neuropathy
- Crystalluria/proteinuria
- Photosensitivity
Sulfonamide specific teaching
- Protect from sun exposure
2. Take with food
Tetracycline medications (Suffix specific)
Antibiotics; -CYCLINE suffix
Tetracycline specific side effects
- Discoloration of primary teeth in fetus if taken during pregnancy! (or early in life)
- PhotoTOXIC reaction
Tetracycline specific teaching
- SPECIAL NOTE TO EXPIRATION DATE
- Use additional contraceptive in addition to oral contraceptives
- SUN EXPOSURE PREVENTION!
Nitrofurantoin (Usage, side effects, interventions)
Used to treat UTI’s
Side Effects: Asthma attacks
Interventions: Avoid acidic foods (i.e. cranberry juice, prunes)
Phenazopyridine (Usage, side effects, interventions)
Used as an urinary tract analgesic
Side Effects: HA and vertigo
Interventions: Urine will be bright ORANGE
Anti-impotence medication (Suffix specific)
Used to treat erectile dysfunction; -AFIL suffix
Anti-impotence specific teaching
- No grapefruit juice
2. NEVER use with nitrates or alpha-blockers (could be fatal)
Anticholinergic medications (STrIP BAT)
- Scopolamine
- Trihexyphenydil (Psych)
- Iprotropium (Resp.)
- Propantheline
- Benzotropine (Psych)
- Atropine
- Tiotropium (Resp.)
Anticholinergic specific side effects
- Dry mouth
- Blurred vision
- Urinary retention
Anticholinergic specific teaching
- Do NOT use with glaucoma, paralytic ileus, or BPH
2. 30 minutes before meals or 2 hours after
Anticoagulant medications
- Heparin
- Enoxaparin
- Warfarin
Heparin therapeutic range
1.5-2.5x normal PTT (normal 20-45 seconds)
Warfarin therapeutic range
1.5x normal PT (normal 9-12 seconds)
Antidote for heparin
Protamine sulfate
Antidote for warfarin
Vitamin K
Foods that should be avoided when taking Warfarin
Anything high in vitamin K!
- Green vegetables
- Pork
- Rice
- Yogurt
- Cheeses
- Fish
- Milk
Clients on anti-coagulation therapy should avoid…
- IM injections
- Aspirin
- NSAID
Herbal interactions with warfarin (3 G’s)
- Ginger
- Ginkgo
- Garlic
Anti-convulsant medications
- Clonazepam* (Benzo)
- Diazepam (Benzo)
- Fosphenytoin
- Levetricetam
- Phenytoin sodium*
- Phenobarbital*
- Magnesium sulfate (OB)
- Valproic acid*
- Carbameazepine*
- Gabapentin*
- Lamotrigine*
- Topiramate*
Anti-convulsant side effects
- CNS depression (NO ALCOHOL)
- Ginigival hypertrophy (overgrowth of gums)
- Agranulocytosis
- Aplastic anemia
Anti-convulsant nursing interventions
- Do NOT discontinue abruptly
2. Use caution when giving these medications with MAOI’s (lower seizure threshhold)
Phenytoin specific side effects
- Cardiac arrest can occur when given IV
2. Turns urine pink
Valproic acid specific side effects
Don’t take with carbonated beverages
MAOI medications (PIT)
Antidepressant
- Phenelzine sulfate
- Isocarboxazide
- Tranylcypromide
MAOI specific side effects
- Hypertensive crisis!!
- Photosensitivity
- Weight gain
MAOI nursing considerations/teaching
- No tyramine containing foods
- Takes up to 4 weeks to work
- Discontinue 10 days before general anesthesia
Tyramine containing foods
- Aged cheese
- Bologna
- Pepperoni
- Salami
- Figs
- Bananas important to know if taking Lasix as well
- Raisins
- Beer/red wine
A patient presents with a severe headache, palpitations, diaphoresis, and a stiff neck and states they are taking isocarboxazide. What are they presenting with?
Hypertensive crisis
SSRI medications (Suffix specific)
Antidepressant; -PRAM, -INE suffix
**EXCEPT amitryptyline and imipramine
SSRI specific teaching
- Take in the morning
- Monitor for suicide!!
- Do NOT administer with MAOI’s! (Serotonin syndrome risk)
Tricyclic medications (exception -INE’s)
Antidepressant
- Amitriptyline
- Imipramine
Tricyclic specific side effects
- Orthostatic hypotension
2. Anticholinergic effects
Tricyclic specific teaching
- Take dosage at night to decrease sedative effects
- Do NOT stop abruptly
- Avoid exposure to sunlight
Heterocyclic medications (Suffix specific)
Antidepressant/smoking cessation; -ON/ONE suffix
- Buproprion
- Trazodone
Side effects of Buproprion include…
- Insomnia
2. Agitation
Side effects of trazadone include…
- Sedation
2. Orthostatic hypotension
Rapid acting insulin (Types, Onset, Peak)
Types: Lispro, Aspart
Onset: within 15 minutes
Peak: 1-3 hours
Short-acting insulin (Types, Onset, Peak)
Types: Regular
Onset: 30-60 minutes
Peak: 1-5 hours
Intermediate-acting insulin (Types, Onset, Peak)
Types: Isophane (NPH)
Onset: 1-2 hours
Peak: 6-14 hours
Long-acting insulin (Types, Onset, Peak)
Types: Glargine
Onset: 3-4 hours
Peak: None
Type of insulin that can be used in insulin pump
Regular
Oral hypoglycemic medications
- Glimepiride, Glipizide, glyburide
- Metformin
- Arcarbose, Miglitol
- Rosiglitazone, Pioglitazone
- Repaglinide
- Sitagliptin
- Exanatide
Drugs that will interact with oral hypoglycemic medications and increase risk for hypoglycemic events
- MAOI
- Aspirin
- Alcohol
- Sulfonamides
- Oral contraceptives
When should oral hypoglycemic agents be taken?
Before breakfast
Medication used to reverse hypoglycemia
Glucagon
Once glucagon has been administered, it’s important for the nurse to administer what if they client is CONSCIOUS?
Carbohydrates to prevent secondary hypoglycemic reaction
Important nursing assessments for anyone taking diabetic agents
- Nutrition
- Exercise
- Stress
- Pregnancy
Antidiarrheal medication (BOID)
- Bismuth subsalicylate
- Optium alkaloids
- Ioperamide
- Diphenoxylate hydrochloride and atropine sulfate
Common side effects of antidiarrheals
- Constipation
2. Anticholinergic effects
Nursing considerations for antidiarrheals
- Monitor for urinary retention (anticholinergic action)
2. Do NOT administer for abdominal pain of unknown origin
Antiemetic medications (Suffix specific)
- AMIDE, -AZINE endings (plus 3 additional)
1. Ondansetron**
2. Dimenhydrinate**
3. Droperidol**
Major side effect if using antiemetics in conjunction with a viral infection
Reye’s syndrome
Antifungal medications
- Amphotericin B
- Nystatin
- Flucanozal
- Metronidazole
Major side effect of antifungal medications
Hepatotoxicity
Nursing considerations for antifungal medications
- Give with food to decrease GI upset
2. Always check hepatic functioning!
Antigout medications (CAP)
- Colchicine
- Allopurinol
- Probenecid
Which antigout medication will increase the action of ciprofloxacin?
Probenecid
Antigout medications affect the production of…
Uric acid
Major side effect of antigout medications
Renal calculi
Nursing considerations for antigout medications
- Force fluids (3000 mL per day)
2. Give with milk, antacids, or food
Antihistamine medications (Suffix specific)
-MINE, -ZINE, -DINE suffix
Common antihistamine side effects
- Sedation/Drowsiness
- Bronchospasm respiratory effects
- Anticholinergic effects
Nursing considerations for antihistamines
- Administer with food
- Promote hard candies for dry mouth
- Avoid alcohol
Antilipemic Medications (Prefix or Suffix specific)
Affect cholesterol levels; CHOLE- prefix or -STATIN suffix
Nursing considerations for antilipemic medications
- May cause fat-soluble vitamin deficiencies
- Take at night or 30 minutes before meals
- Will inhibit absorption of other medications if taken together
ACE Inhibitors (Suffix specific)
Antihypertensive; -PRIL suffix
Side effects specific to ACE inhibitors
- Rash, pruitis
- Persistent, dry, nonproductive cough
- GI irritation
Nursing considerations specific to ACE inhibitors
- Give 1 hour before meals or 2 hours after (food decreases absorption)
- Increases K levels - monitor labs!
Beta Blocker Medications (Suffix specific)
Antihypertensive; -OLOL suffix
Side effect specific to Beta Blockers
BRONCHOSPASM!
Nursing considerations specific to Beta Blockers
- Do NOT discontinue abruptly (can cause rebound HTN)
- Take WITH meals
- May block signs of hypoglycemia (monitor glucose closely)
- Decreased effectiveness in African Americans
Calcium Channel Blocker Medications (Suffix specific)
Antihypertensive; -IPINE suffix plus 2 different
- Verapamil*
- Diltiazem*
Calcium Channel Block specific nursing considerations
- Avoid grapefruit juice
ARB medications (Suffix specific)
Antihypertensive; -SARTAN suffix
Main antihypertensive side effect and nursing consideration
Hypotension/Orthostatic hypotension
Monitor vital signs and ensure patient safety!
Alpha-1 Adrenergic Blocker Medications (Suffix specific)
Antihypertensive; -AZOSIN suffix
Side effects specific to Alpha-1 Adrenergic Blockers
- Reflex tachycardia
2. Nasal congestion
Main nursing consideration when giving an Alpha-1 Adrenergic Blocker
Administer first dose at bedtime to avoid fainting
Centrally acting Alpha Adrenergic medications
Antihypertensive
- Clonidine
- Methyldopa
Nursing consideration specific to Centrally Acting Alpha Adrenergic medications
Don’t discontinue abruptly
Direct acting vasodilator medications
Antihypertensive
- Hydralazine
- Minoxidil
Direct acting vasodilator specific side effects
- Increased hair growth
2. Tachycardia
Nursing consideration when administering direct acting vasodilators
Check pulse BEFORE taking medication
Bipolar Disorder Medications
- Lithium
- Carbamazepine
- DIvalproex sodium
Target therapeutic level for lithium
1 to 1.5 mEq
Patients taking lithium should have a daily fluid intake of at least…
2500-3000 mL per day
Common side effects of bipolar medications
- Tremors
2. Polydipsia, polyuria (DI)
Prefixes and Suffixes related to antibiotics
-MYCIN CEF- -FLOXACIN -CILLIN SULF- -CYCLINE
Suffixes related to antihypertensives
- PRIL
- OLOL
- IPINE
- SARTAN
- AZOSIN