Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Cardiovascular Drugs > Medications > Flashcards

Medications Flashcards

0
Q

EPINEPHRINE

A 
INCREASES
Systemic vascular resistance 
Systolic & Diastolic blood pressure 
Electrical activity in the Myocardium
Coronary & cerebral blood flow 
Strength of myocardial contraction 
Myocardial oxygen requirements 
Automaticity 
Peripheral Vasoconstriction 
Coronary perfusion pressure
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Receptor- Stimulation

A

a= alpha , B=beta
A1 = vasoconstriction
a2=Peripheral Vasodilation
B1= increases heart rate & myocardial contractility
B2= relaxation of bronchial, uterine, GI Smooth muscle.
Modulates fat metabolism & drives K+ into the cell
Stimulates the release of RENIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

USES OF EPINEPHRINE

A

Indicated in VFib, Pulseless VTach, Asystole , PEA

Can be used for severe Brady , Hypotension or cardiac arrest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

VASOPRESSIN : Levephed ( Nonepinephine)
For Hypotension
Can increase heart rate
De

A

Contractions of blood vessels both peripheral and central
Can cause decrease secretion
I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

ATROPINE: inhibit ACETYLCHOLINE cause increase heart rate Decrease secretions AFib - Flutty

A

Used in symptomatic or relative bradycardia

Caution in 2 nd degree heart blocks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

ADRENERGIC

A

Dopamine
Dopitamine
Epinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

ANTI-CHOLINERGIC
Atropine, Scopolamine
Indications
Bradycardic

A

Mode of action
Increase heart rate , increase CO
Inhibit Parasympathetic nerve , impulse by selectivity binding acetylcholine to it receptor nerve cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

VASODILATORS
NITROGLYCERIN, SODIUM, NITROPRUSSIDE

Used for Hypertension Angina

A

ACTION

Decrease BP, Increase tissue Perfusion, Relaxation of vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q 
ANTICOAGULANTS 
1. Heparin ( Reverse Agent is PROTAMINE)
2 Coumadin 
                Used
DVT, PE, Stroke, PCI
A 
ACTION 
Many different caution depends on drug
1. Coumadin ( vitamin K antagonist)
2. Heparin ( activate antithrombin 
3. Lovenox( Direct Factor Xa inhibitors Argatroban direct Thrombin inhibit reversed & Repolarization of excitable membranes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

NITRATES
Nitropaste, Nytroglycein
Lower BP by Enhancing NO activity at Endothelial Level
Causes Vasodilation of smooth muscle in vascular wall
Decrease in Preload which results in decrease BP Which Reduces LV work and decrease Oxygen demand

A

Indications
Hypertension: ( systemic
Angina: ( coronary artery relaxation to increase flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ANTIRRHYTHMIC

  1. Digoxin
  2. Amiodarone,
  3. Procainamide
       Used Treat arrhythmia such as: VT,VFIB a fib, A flutter
A

Action

Suppress abnormal rhythms of the heart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CALCIUM CHANNEL BLOCKERS : inhibit movement of calcium Ions cross membranes of cardiac & arterial muscle cells Result in depression of Impulse formation in cardiac cells
Negative dromotropic, negative Inotropic
Dilation of coronary arteries & arterioles
Decreased cardiac work
1. Verapamil (Calan
Breaks coronary, vasospasm, breaks PSVT
2. Dltiazam( cardizem)
Angina & atrial
3. Nifedipine( procardia)
Vasodilation = lowered BP

 Used for hypertension A fib / flutter tachycardia
A 
Action
Decrease HR Smooth muscle 
Relaxation ( vasodilation) for IC  
   Indications 
Angina long term management 
Hypertension 
SVT Particularly those related to DIGOXIN 
slow / No Reflow situations
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

BETA BLOCKERS: Mechanism of action : PROPRANOLOL (inderal), ATENOLOL ( Tenormin), Labetalol ( Normodyne, Trandate)
1. Decrease the myocardial demand for oxygen
2. BETA 1 selective blockade
Negative Chronotropic
Negative Inotropic
These actions decrease Myocardial demand & decrease the Workload of the Heart

A

Beta blockers indications
Angina : long term management
Arrhythmias
Hypertension
HOCM
Prevention of reinfarction in clinically stable patients when started 1-4 was after MI
Bradycardia and heart blockers with bradycardia
Cardiogenic shock , CHF, Bronchial Asthma or spams

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

ACE INHIBITORS : Action
Blocke Angiotensin Converting Enzyme in the lungs from converting Angiotensin I , Activated the KIDNEYS to Renin is released from the Kidneys to Angiotensin II Which is a VASOCONSTRICTOR
Results in Anti- Hypertension properties

A 
Indications
Hypertension 
Treat mood CHF, Stable patients within 24hrs of AMI to improve survival 
   Ex: Captopril 
         Enalapril
         Lisinopril
          Quinacrine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Anti- Arrythmics Classes
1: Class Ia : Procanamide prolongs action potential
2: Ib Lidocaine: shortens action potential
3 Ic Flecanide Na channel blocker slows conduction
4: II Propranolol beta blocker
5: III Amiodarone blocks Potassium Chanel and prolongs Repolarization

A

Amiodarone
150mg IVP VT Patients that feel palpitations or are alive
300mg IVT FOR VFIB patients
Pulseless VFib or patients that are dead

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SYMPATHETIC = ADRENERGIC

A 
Affect the atria & the ventricle 
 Increase HR Conduction & irritability 
"Fight or Fight "
Increase Blood Sugar 
Responds to immediate treat or stress 
 Epinephrine, Norepinephrine
16
Q

Drugs that stimulate the Sympathetic nervous system

A

ADRENERGIC
ADRENERGIC agonists
Sympathominetics
Catecholamines

17
Q

CATECHOLAMINES

A 
Substance which produce a sympathominetics response are either 
Natural or Endogenous = 
Epinephrine norepinephrine 
   Or synthetic or exogenous =
     Isoproternol, Dobutamine
18
Q

PARASYMPATHETIC = Choligenic
Affect the atria
Decrease HR and Conductivity

A 
Control body process 
 Eating 
Resting 
Sleeping
Digestion
19
Q

ADENOSINE

A

Slows conduction through AV node

Interrupts AV node re entry

20
Q

MAGNESIUM

A

Co factor in numerous enzymatic
Decrease mg associated with Dysrhythmics can precipitate VFIB
May reduce post MI Ventricular Dysrhythmias
Treatment of choice for Torsades de pointes

21
Q

MORPHINE SULPHATE

A 
Increase venous capacitance 
Decrease SVR
Decrease Pulmonary Congestion 
Decrease myocardial oxygen demand 
Given for Pain, Anxiety, Pulmonary edema
22
Q

AMRINONE

A

Rapid acting Inotrope

For severe CHF refractory vasodilator and conventional Inotropics

23
Q

IIb / IIIa INHIBITORS

A

GLYCOPROTEINS IIb/ IIIa Inhibitors recommend for a patients with no ST segment elevation MI OR High risk Unstable Angina
Platelets aggregation is the final common pathway bod formation of a platlet drug

FIBRINOGEN and VON WILLEBRAND FACTOR links the Platelets together by binding to GP IIb/ IIIa molecules on adjacent platelets aggregate into a hemostatic plug

24
Q

GYCOPROTEIN IIb/ IIIa Drugs

A

ABCIXIMAD ( ReoPro)

INTEGRELIN

AGGRASTAT

25
Q

ABCIXIMAD ( ReoPro)

A

Used as an adjunct to PCI to prevent Ischemic complications
Use with heparin and ASA

Emergency reversal for ReoPro is platelet infusion

26
Q

INTEGRELIN

A

Used for treatment of ACS including patients to be managed medically and those undergoing PCI
Concurrent use heparin and ASA

27
Q

AGGRASTAT

A

Used in combo with heparin
For treatment of ACS including patients who are managed medically and those undergoing PCTA or ATHRECTOMY

Emergency reversal for AGGRASTAT is discontinue and wait for renal clearance

Cardiovascular Drugs (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions