MEDICATIONS Flashcards
what is the mechanism of salbutamol?
a short-acting B2-agonist that causes bronchodilation
what is the mechanism of ipratropium bromide?
an anticholinergic drug that causes bronchodilation and helps to dry up mucous. longer acting than beta-agonist medications
what is the mechanism of adrenaline?
Adrenaline is a sympathomimetic catecholamine that is a nonselective agonist for alpha-adrenergic and beta-adrenergic receptors. It has a greater affinity for beta receptors in small doses. However, large doses produce selective action on alpha receptors. The actions on alpha-1 receptors, increasing vascular smooth muscle contraction, pupillary dilator muscle contraction, and intestinal sphincter muscle contraction. Other significant effects include increased heart rate, myocardial contractility, and renin release via beta-1 receptors. Beta-2 effects produce bronchodilation,
what type of drug is aspirin and what is the mechanism of action?
Aspirin is an antiplatelet.
Aspirin decreases the production of prostaglandins by inhibiting the COX enzyme.
It blocks thromboxane A2 on platelets in an irreversible fashion preventing platelet aggregation.
what is the mechanism of GTN?
GTN is a vasodilator that causes the relaxation of vascular smooth muscle.
what is the mechanism of methoxyflurane?
Methoxyflurane is an anaesthetic agent. This agent interferes with the release and re-uptake of neurotransmitters at post-synaptic terminals, and/or alters ionic conductance following receptor activation by a neurotransmitter, thereby disrupting neuronal transmission. In addition, this agent activates the inhibitory receptor gamma-aminobutyric acid (GABA).
what is the mechanism of ondansetron?
Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin
what is the action of midazolam?
Midazolam binds to the GABA receptor but does not displace GABA; rather, it enhances the affinity of GABA for its receptor site on the same receptor complex. It also has a high affinity for benzodiazepine receptors. Midazolam activates chloride channels, hyperpolarising the membrane and causing neuronal inhibition. The anticonvulsant activity of midazolam is related to the excess GABA action on motor circuits in the brain.
what is the mechanism of naloxone?
