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Psych - Mental Health > Medications > Flashcards

Medications Flashcards

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1
Q

Psychodynamics

A

Where the drugs act in the body

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2
Q

Agonists

A

Medication that will elicit the same effect as a neurotransmitter

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3
Q

Antagonists

A

Medication that blocks the effect of a neurotransmitter

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4
Q

Partial agonists

A

Mimics the effect of a neurotransmitter but not to the full extent

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5
Q

Reuptake

A

Increases the availability of the neurotransmitter

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6
Q

Efficacy

A

Efficiency, the ability of the drug to produce a response

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7
Q

Toxicity

A

Once a medication gets to 100%, it can get toxic

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8
Q

Therapeutic index

A

Ratio of max nontoxic dose to min effective dose

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9
Q

Pharmacokinetics

A

How the body acts on the drug

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10
Q

Metabolism happens in

A

mostly the liver, sometimes in kidneys

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11
Q

Aging

A

-Slows everything down
-Gastric absorption, renal function, liver metabolism

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12
Q

AP Indications

A

Schizophrenia, Mania, Autism, Psychosis

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13
Q

AP Metabolism

A

Liver

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14
Q

AP Medications Types

A

-Typical
-Atypical

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15
Q

Typical AP Meds

A

-Antagonists
-Blocks dopamine
-Works for + symptoms

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16
Q

Chlorpromazine

A

-Thorazine
-Typical
-First AP med
-comes in IM form

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17
Q

Fluphenazine

A

-Prolixin
-Typical
-IM, PO, Liquid, LAI

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18
Q

Haloperidol

A

-Haldol
-Typical
-IM, PO, Liquid, LAI
-AE: Tardive

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19
Q

Atypical AP Meds

A

-Antagonists
-Blocks dopamine
-Weaker than typical
-Works for + and - symptoms

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20
Q

Aripiprazole

A

-Abilify
-Atypical
-PO, LAI

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21
Q

Clozapine

A

-Clozaril
-Atypical
-Last resort
-AE: Agranulocytosis

22
Q

Risperidone

A

-Risperdal
-Atypical
-PO, Liquid, SQ LAI
-AE: Metabolic Syndrome

23
Q

Ziprasidone

A

-Geodon
-Atypical
-AE: prolongs QT interval

24
Q

Paliperidone

A

-Invega
-Atypical
-PO, LAI
-AE: photosensitivity

25
Q

Lurasidone

A

-Latuda
-Atypical
-Education: take with food

26
Q

Cariprazine

A

-Vraylar
-Atypical
-High efficacy
-Education: take w/ or w/o food: must choose one and stick with it

27
Q

Asenapine

A

-Saphris
-Atypical
-SL

28
Q

LAI Education

A

-Ask if they took any PO of the meds before
-How did they tolerate it
-LAIs last for weeks

29
Q

AP Side effects

A

-Orthostatic hypotension
-Lowered seizure threshold
-Neuroleptic Malignant Syndrome (NMS)
-Photosensitivity
-Anticholinergic (DRY)
-DM
-Prolonged QT interval
-Movement disorders**
-Weight gain
-Sex stuff

30
Q

Acute Extrapyramidal Syndrome

A

-Movement disorder
-Usually in atypical AP
-Symptoms include…
-Dystonia (involuntary muscle spasm)
-Oculogyric crisis (eyes roll back and gets stuck)
-Pseudoparkinsonism
-Akathisia (restlessness)
-Akinesia (slow movements)
-Treatment include…
-Benztropine
-Propranolol

31
Q

Tardive Dyskinesia

A

-Movement disorder
-Usually in typical AP
-Causes: long-term AP use
-Irreversible if not treated
-Symptoms include…
-Constant involuntary rhythmic movements
-Treatments include:
-Decrease dose
-Change medications
-Try d/c meds but it can make it worse
-Valbenazine
-Austedo

32
Q

Metabolic Syndrome

A

-Usually in atypical AP
-Symptoms include…
-Obesity
-DM
-Hyperlipidemia

33
Q

Neuroendocrine

A

-Symptoms include…
-Hyperprolactinemia
-Gynecomastia
-Galactorrhea
-Menstrual irregularities

34
Q

Neuroleptic Malignant Syndrome

A

-Usually with typical
-Symptoms include…
-Confusion
-LOC changes
-High fever
-Agitation
-Muscular rigidity
-BP irregularities
-Treatment include…
-Dantrolene
-Bromocritine

35
Q

Agranulocytosis

A

-Symptoms include…
-Low WBC levels
-Infection
-Death

36
Q

Lithium

A

-Mood stabilizer
-For mania, depressive episodes of BPD
-Gold standard
-Only med that is efficacious against suicidal ideation
-Kidney metabolism
-Therapeutic level: 0.6-1.2
-Side effects include…
-Fine head tremors
-Drowsiness
-Metallic taste
-Thirst
-Increased urinary frequency
-Mild diarrhea
-Adverse toxic effects include…
-Drowsiness
-Vomiting
-Muscular weakness
-Lack of coordination
-Severe diarrhea

37
Q

Anticonvulsants

A

-Valproic Acid: liver metabolism
-Carbamazepine: agranulocytosis
-Lamotrigine: Stevens Johnsons Syndrome (rash) happens if titrated too quickly, never restart if missed >3 days

38
Q

Antidepressants

A

-Takes up to 2-6 weeks
-D/C should be tapered off
-Increases risk of SI in children
-AE: Serotonin Syndrome (w/ >2 SSRI)

39
Q

SSRI

A

-antidepressant
-serotonin
-depression, anxiety

40
Q

SNRIS

A

-antidepressant
-serotonin, norepinephrine
-venlafaxine/desvenlafaxine CI in close angled glaucoma

41
Q

NDRI

A

-antidepressant
-serotonin, norepinephrine, dopamine
-CI in eating disorders
-can end smoking

42
Q

NASSA

A

-antidepressant
-serotonin, norepinephrine, noradrenalin
-packs on weight (15lbs), sedating

43
Q

SARI

A

-antidepressant
-serotonin
-Ex: trazodone (priapism)

44
Q

TCAs

A

-antidepressant
-serotonin, norepinephrine
-fatal in overdose

45
Q

MAOIs

A

-antidepressant
-HTN if tyramine (aged cheese, meat, wine, chocolate)
-Isocarboxazid, Phenelzine, Tranylcypromine, Selegiline

46
Q

Serotonin Syndrome Sx

A

-mental status changes (hallucinations, agitation)
-neuromuscular problems (hyperreflexia, incoordination)
-instability (tachycardia, hyperthermia, BP)
-GI (N/V, diarrhea)

47
Q

Benzodiazepines

A

-Antianxiety
-very addicting
-short-term use

48
Q

Nonbenzodiazepines

A

-Antianxiety
-Not addicting
-Long-term use

49
Q

Sedative-Hypnotics

A

-Antihistamines: hydroxyzine (PRN, not addictive)

50
Q

Stimulants

A

-weight loss
-children must have EKG
-monitor BP, can stunt growth in children

51
Q

Herbal supplements

A

-ask if pt is taking supplements or OTC meds
-St John’s Worts: works on serotonin so risk for SS

Psych - Mental Health (1 decks)

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