Medications Flashcards
Istretinoin Adverse Effects
Teratogenic
Pseudotumor Cerebri
Hypertriglyceridemia
Transaminase Elevation
A-Fib Treatment No CAD or Structural Heart Disease
Flecainide (1C)
Propafenone (1C)
A-Fib Treatment Left Ventricular Hypertrophy
Class 1C contraindicated
Dronedarone (III)
Amiodarone (III)
A-Fib CAD without Heart Failure
Class 1C contraindicated
Sotalol (III)
Dronedarone
A-Fib with Heart Failure EF <35%
Class 1C, Sotalol, Dronedarone contraindicated
Amiodarone
Dofetilide (III)
Adenosine
used to help identify rapid narrow complex tachycardia
Valproic acid Adverse Effects
Thrombocytopenia
hepatotoxicity
pancreatitis
teratogen
Beta Blocker Toxicity
hypotension, confusion
treatment: glucagon (antidote)
atropine for bradycardia
Drugs implicated in pancreatitis
Isoniazid
tetracyclines
valproic acid
thiazides
NSAIDs
suldasalazine
Vancomycin Infusion Reaction (red man syndrome)
due to direct mast cell activation
muscle cramps
transient hypotension
body flushing
pruritus
treatment: Diphenhydramine
Herbal medication with increased bleeding risk
Ginkgo Biloba
Ginseng
Saw Palmetto
Herbal Medications with possible hepatic injury
Black Cohosh
Kava
Warfarin immediate reversal
Prothrombin Complex Concentrate (PCC)
Mechanical Heart Valve anticoagulation treatment
only acceptable is warfarin
INR <4.5 minimal or no bleeding
hold warfarin for 1 or 2 days or decrease the dose