Medications Flashcards

1
Q

Istretinoin Adverse Effects

A

Teratogenic
Pseudotumor Cerebri
Hypertriglyceridemia
Transaminase Elevation

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2
Q

A-Fib Treatment No CAD or Structural Heart Disease

A

Flecainide (1C)
Propafenone (1C)

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3
Q

A-Fib Treatment Left Ventricular Hypertrophy

A

Class 1C contraindicated
Dronedarone (III)
Amiodarone (III)

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4
Q

A-Fib CAD without Heart Failure

A

Class 1C contraindicated
Sotalol (III)
Dronedarone

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5
Q

A-Fib with Heart Failure EF <35%

A

Class 1C, Sotalol, Dronedarone contraindicated
Amiodarone
Dofetilide (III)

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6
Q

Adenosine

A

used to help identify rapid narrow complex tachycardia

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7
Q

Valproic acid Adverse Effects

A

Thrombocytopenia
hepatotoxicity
pancreatitis
teratogen

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8
Q

Beta Blocker Toxicity

A

hypotension, confusion
treatment: glucagon (antidote)
atropine for bradycardia

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9
Q

Drugs implicated in pancreatitis

A

Isoniazid
tetracyclines
valproic acid
thiazides
NSAIDs
suldasalazine

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10
Q

Vancomycin Infusion Reaction (red man syndrome)

A

due to direct mast cell activation
muscle cramps
transient hypotension
body flushing
pruritus
treatment: Diphenhydramine

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11
Q

Herbal medication with increased bleeding risk

A

Ginkgo Biloba
Ginseng
Saw Palmetto

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12
Q

Herbal Medications with possible hepatic injury

A

Black Cohosh
Kava

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13
Q

Warfarin immediate reversal

A

Prothrombin Complex Concentrate (PCC)

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14
Q

Mechanical Heart Valve anticoagulation treatment

A

only acceptable is warfarin

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15
Q

INR <4.5 minimal or no bleeding

A

hold warfarin for 1 or 2 days or decrease the dose

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16
Q

INR 4.5-10 minimal or no bleeding

A

hold warfarin and resume when INR is therapeutic
give low dose vitamin K (oral 1-2.5mg) if increased risk of bleeding

17
Q

INR >10 minimal or no bleeding

A

hold warfarin and administer high dose vitamin K (oral 2.5-5mg)