Medication Administration

Question 1

Bioavailability

Answer 1

The amount of drug that enters central circulation and is able to cause and effect.

Question 2

Bolus

Answer 2

Administration of medication in single dose (as opposed to and infusion)

Question 3

Concentration

Answer 3

For calculation purposes, this is the total amount of medication available as packaged, e.g., total amount of drug (mcg, mg, g) in the syringe, ampule, etc.

Question 4

Dose

Answer 4

The drug amount intended for administration.

Question 5

Enteral

Answer 5

Delivery of medication trough the GI tract (oral, sublingual, rectal).

Question 6

Half Life

Answer 6

Period of time required for concentration of drug in the body to be reduced by one-half.

Question 7

LD50 (Lethal dose 50)

Answer 7

Is the amount of an ingested substance in (mg/kg) that kills 50% of a test sample.

Question 8

Parenteral

Answer 8

Delivery of medication outside of the GI tract, e.g., IV, IO, IM, SQ, intranasal.

Question 9

Pharmacokinetics

Answer 9

Movement of a drug through the body, includes absorption, bioavailability, distribution, metabolism, and excretion.

Question 10

Pharmacodynamics

Answer 10

The mechanism of action of a medication.

Question 11

Therapeutic index

Answer 11

The range between minimum effective dose of a medication and the maximum safe dose. The narrower, the more risk associated with the medication.

Question 12

Volume

Answer 12

For calculation purposes, this is the total amout of fluid available as packaged, e.g., total amount of fluid (mL) in the syringe, ampule, etc.