Medication Flashcards

1
Q

A patient with kidney transplant is prescribed with Tacrolimus. Which of the following statement from the patient requires further teaching from the nurse?
a. “I will need to get my blood check for the tacrolimus level in the morning before I take my medication.”
b. “I will report to the doctor if my blood pressure is high.”
c. “It is expected to have decrease urine after I start this medication.”
d. “The level of the medication may need to adjust depends on the blood work.”

A

c.

Tacrolimus can cause nephrotoxicity, neurotoxicity (tremor), hypertension, hyperkalemia. It has a narrow therapeutic range (7-20 ng/mL). The medication may need adjustment depends on the serum Tacrolimus. Patient will get the blood drawn before the morning dose. Due to the renal toxicity from the medication, it is important for the patient to report to the provider.

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2
Q

A nurse is caring for a patient with new kidney transplant. Which of the following will the nurse take immediate action?
a. patient complaint of swollen and painful feet
b. patient noticed excessive hair growth on his legs
c. Laboratory result of BUN 45 and Creatinine 2.1
d. Blood pressure of 135/85

A

c.

Cyclosporine is a medication given to patient who has organ transplant. This medication can prevent transplant rejection. However, it comes with many side effects. Nephrotoxicity, neurotoxicity (tremor), gingival hyperplasia, hypertension, hyperlipidemia, gout, hirsutism. An increase of BUN and creatinine signaling decreased kidney function. It is a sign of nephrotoxicity. Swollen and painful feet may indicate increase uricemia (gout). It may need intervention and medication (allopurinol) to lower uric acid, however, it is not priority. Excessive hair growth which indicate hirsutism. This does not require immediate action.
Cyclosporine may cause increase blood pressure, cholesterol. A BP of 135/85 may need intervention after nephrotoxicity has taken care of.

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3
Q

Which of the following is the side effect of cyclosporine? Select all that apply.
a. swollen gum
b. increase blood pressure
c. unstable gait
d. decrease cholesterol
e. tremor
f. hair loss

A

a, b, e

Hypertension, hyperlipidemia, gingival hyperplasia, tremor, hirsutism, tremor, nephrotoxicity are side effects of cyclosporine

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4
Q

Which of the following statement indicate that the patient understanding the teaching of cyclosporine?
a. “I should take the medication with grapefruit for better absorption.”
b. “I need to have my blood drawn for the serum cyclosporine level everyday when I start this medication.”
c. “It does not require to take this medication with food.”
d. “It is expected to have high blood pressure when taking this medication.”

A

b.

Cyclosporine has very narrow therapeutic range. Patient who start this medication may need to have blood work done everyday for the dose to be adjusted.

Avoid grapefruit which will alter the dosage of the medication. This medication needs to take with food to avoid GI upset. Hypertension, tremor, nephrotoxicity, gout, hirsutism, gingival hyperplasia are side effects of cyclosporine. Patient should report to MD if they occurs.

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